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公开(公告)号:US20120082724A1
公开(公告)日:2012-04-05
申请号:US13285470
申请日:2011-10-31
申请人: THOMAS BUCH-RASMUSSEN , Søren Aasmul , James M. Flink , Philip Hansen , Jens Ulrik Poulsen , Claus Juul-Mortensen
发明人: THOMAS BUCH-RASMUSSEN , Søren Aasmul , James M. Flink , Philip Hansen , Jens Ulrik Poulsen , Claus Juul-Mortensen
CPC分类号: A61K9/145 , A61K9/0024
摘要: Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.
摘要翻译: 用于肠胃外注射的固体药物组合物,其包含粘合剂和至少一种治疗剂。 药物组合物具有直接注射使用插管等的强度。
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公开(公告)号:US06485453B1
公开(公告)日:2002-11-26
申请号:US09548957
申请日:2000-04-13
申请人: Thomas Buch-Rasmussen , Søren Aasmul , James M. Flink , Philip Hansen , Claus Juul-Mortensen , Jens Ulrik Poulsen
发明人: Thomas Buch-Rasmussen , Søren Aasmul , James M. Flink , Philip Hansen , Claus Juul-Mortensen , Jens Ulrik Poulsen
IPC分类号: A61M3100
CPC分类号: A61M37/0069 , A61M31/007 , A61M2205/123
摘要: A cassette for storing and insertion of a solid medicine peg appears as a unit having a first bore (2) which accommodates the medicine peg (3) and has a diameter corresponding to the diameter of this peg (3), a second bore (4) in coaxial extension of the first bore (2) and having a diameter larger than the diameter of the first bore (2), an inserter having a shaft (5) fitting into the first bore (2) and a guiding head (6) in coaxial extension of the shaft (5) fitting into the second bore. The inserter shaft (5) has one end adjacent to the peg (3) and the other connected to the guiding head (6) which projects from the cassette. The head (6) fits into the second bore with a fitting providing a diffusion tight sealing and the distal end of the unit is closed by a membrane diffusion tightly sealing this distal end.
摘要翻译: 用于存放和插入固体药物栓钉的盒子出现为具有容纳药物钉(3)的第一孔(2)的单元,并且具有对应于该栓钉(3)的直径的直径,第二孔(4) ),其具有大于所述第一孔(2)的直径的直径,所述插入器具有装配到所述第一孔(2)中的轴(5)和引导头(6) 在轴(5)的同轴延伸中装配到第二孔中。 插入器轴(5)具有与钉(3)相邻的一端,另一端连接到从盒突出的引导头(6)。 头部(6)通过具有扩散密封的配件装配到第二孔中,并且单元的远端通过密封该远端的膜扩散来封闭。
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公开(公告)号:US06660197B1
公开(公告)日:2003-12-09
申请号:US09689189
申请日:2000-10-12
申请人: Thomas Buch-Rasmussen , Søren Aasmul , James M. Flink , Philip Hansen , Claus Juul-Mortensen , Jens-Ulrik Poulsen
发明人: Thomas Buch-Rasmussen , Søren Aasmul , James M. Flink , Philip Hansen , Claus Juul-Mortensen , Jens-Ulrik Poulsen
IPC分类号: B29B1112
CPC分类号: A61J3/06 , A61J2200/20 , B30B11/16
摘要: The present invention relates to a method and a system for producing an elongated drug formulation being suitable for being injected through the skin of a patient with-out the use of a needle or a cannula. The drug formulation is produced by compressing a drug granulate in cavity of a system comprising a roller and a surface, wherein the roller roles over the surface thereby comprising the granulate to the formulation.
摘要翻译: 本发明涉及用于生产细长药物制剂的方法和系统,该方法和系统适用于通过使用针或套管而通过患者的皮肤注射。 药物制剂通过在包含辊子和表面的系统的腔体中压缩药物颗粒而制备,其中辊子在表面上的角色,由此包含制剂的颗粒。
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公开(公告)号:US08518430B2
公开(公告)日:2013-08-27
申请号:US13285470
申请日:2011-10-31
申请人: Thomas Buch-Rasmussen , James M. Flink , Jens Ulrich Poulsen , Søren Aasmul , Philip Hansen , Claus Juul Mortensen
发明人: Thomas Buch-Rasmussen , James M. Flink , Jens Ulrich Poulsen , Søren Aasmul , Philip Hansen , Claus Juul Mortensen
CPC分类号: A61K9/145 , A61K9/0024
摘要: Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.
摘要翻译: 用于肠胃外注射的固体药物组合物,其包含粘合剂和至少一种治疗剂。 药物组合物具有直接注射使用插管等的强度。
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公开(公告)号:US08084053B2
公开(公告)日:2011-12-27
申请号:US12462794
申请日:2009-08-07
申请人: Thomas Buch-Rasmussen , James M. Flink , Jens Ulrich Poulsen , Søren Aasmul , Philip Hansen , Claus Juul Mortensen
发明人: Thomas Buch-Rasmussen , James M. Flink , Jens Ulrich Poulsen , Søren Aasmul , Philip Hansen , Claus Juul Mortensen
CPC分类号: A61K9/145 , A61K9/0024
摘要: Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.
摘要翻译: 固体药物组合物和用于肠胃外注射的制备和施用的方法,包括粘合剂和至少一种治疗剂。 药物组合物具有直接注射使用插管等的强度。
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公开(公告)号:US07666844B2
公开(公告)日:2010-02-23
申请号:US11052645
申请日:2005-02-07
申请人: Thomas Buch-Rasmussen , James M. Flink , Jens Ulrich Poulsen , Søren Aasmul , Philip Hansen , Claus Juul Mortensen
发明人: Thomas Buch-Rasmussen , James M. Flink , Jens Ulrich Poulsen , Søren Aasmul , Philip Hansen , Claus Juul Mortensen
CPC分类号: A61K9/145 , A61K9/0024
摘要: Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.
摘要翻译: 用于肠胃外注射的固体药物组合物,其包含粘合剂和至少一种治疗剂。 药物组合物具有直接注射使用插管等的强度。
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公开(公告)号:US20100196477A1
公开(公告)日:2010-08-05
申请号:US12462794
申请日:2009-08-07
申请人: Thomas Buch-Rasmussen , Søren Aasmul , James M. Flink , Phillip Hansen , Claus Juul , Jens Ulrich Poulsen
发明人: Thomas Buch-Rasmussen , Søren Aasmul , James M. Flink , Phillip Hansen , Claus Juul , Jens Ulrich Poulsen
IPC分类号: A61K38/00 , A61K39/00 , A61K38/28 , A61K38/26 , A61K38/22 , A61K38/18 , A61K38/21 , A61K9/00 , B29C35/02
CPC分类号: A61K9/145 , A61K9/0024
摘要: Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.
摘要翻译: 固体药物组合物和用于肠胃外注射的制备和施用的方法,包括粘合剂和至少一种治疗剂。 药物组合物具有直接注射使用插管等的强度。
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公开(公告)号:US20090111752A1
公开(公告)日:2009-04-30
申请号:US12343722
申请日:2008-12-24
CPC分类号: C07K14/605 , A61K38/26
摘要: Pharmaceutical formulations of GLP-1 compounds and methods for preparation thereof.
摘要翻译: GLP-1化合物的药物制剂及其制备方法。
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公开(公告)号:US20090075895A1
公开(公告)日:2009-03-19
申请号:US12325348
申请日:2008-12-01
申请人: Hanne Nedergaard , Lars Linggaard Hansen , Niels Kristian Klausen , Troels Kornfelt , James M. Flink
发明人: Hanne Nedergaard , Lars Linggaard Hansen , Niels Kristian Klausen , Troels Kornfelt , James M. Flink
CPC分类号: A61K47/183 , A61K9/0019 , A61K47/26
摘要: The invention concerns a composition comprising; i) Modified Factor VII; ii) an agent suitable for keeping the pH of said composition in the range of 4 to 7 when said composition is dissolved in water; and iii) a moisture content of at the most 3%.
摘要翻译: 本发明涉及一种组合物,其包含: i)修饰因子VII; ii)当所述组合物溶解在水中时,适于将所述组合物的pH保持在4至7范围内的试剂; 和iii)水分含量最多3%。
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公开(公告)号:US08846618B2
公开(公告)日:2014-09-30
申请号:US12785861
申请日:2010-05-24
IPC分类号: A61K38/26 , A61P3/10 , A61P7/12 , C07K14/605
CPC分类号: C07K14/605 , A61K38/26
摘要: Pharmaceutical formulations of GLP-1 compounds and methods for preparation thereof.
摘要翻译: GLP-1化合物的药物制剂及其制备方法。
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