公开(公告)号：US20170010280A1

公开(公告)日：2017-01-12

申请号：US15111513

申请日：2015-01-14

申请人： TOKYO METROPOLITAN GERIATRIC HOSPITAL AND INSTITUTE OF GERONTOLOGY ,  KURUME UNIVERSITY

发明人： Masashi TANAKA ,  Masafumi ITO ,  Yasunori FUJITA ,  Yasutoshi KOGA

IPC分类号： G01N33/68 ,  G01N33/74 ,  C12Q1/68

CPC分类号： G01N33/6893 ,  C07K16/22 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N33/6863 ,  G01N33/6872 ,  G01N33/74 ,  G01N2333/475 ,  G01N2333/4753 ,  G01N2333/52 ,  G01N2800/00 ,  G01N2800/04

摘要： To obtain data associated with a mitochondrial disease, a method includes measuring the level of at least one protein selected from the group consisting of GDF15 (growth differentiation factor 15), HGF (hepatocyte growth factor), MIG (gamma interferon induction monokine), SCF (stem cell factor) and SCGF-β (stem cell growth factor beta) in a biological sample collected from a subject. The measured protein level is compared to that of control subjects and then it is checked whether or not there is difference between the protein level of the subject and that of control subjects.

摘要翻译： 为了获得与线粒体疾病相关的数据，一种方法包括测量至少一种选自GDF15（生长分化因子15），HGF（肝细胞生长因子），MIG（γ干扰素诱导单核因子），SCF （干细胞因子）和SCGF-β（干细胞生长因子β）在从受试者收集的生物样品中。 将测量的蛋白质水平与对照受试者进行比较，然后检查受试者的蛋白质水平与对照受试者的蛋白质水平之间是否存在差异。