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公开(公告)号：US20190264541A1
公开(公告)日：2019-08-29
申请号：US16408824
申请日：2019-05-10
发明人： Christian HURTEVENT , Salima BARAKA-LOKMANE , John-Richard ORDONEZ-VARELA , Olivier TILLEMENT , Thomas BRICHART , Mattéo MARTINI
摘要： A method for adjusting, to a pre-determined value, the level of a mineral deposition or corrosion inhibitor injected into a gas or oil well. Using of the time-resolved fluorescence method for detecting and quantifying a mineral deposition or corrosion inhibitor in a fluid from an oil or gas production well.
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公开(公告)号：US20170002629A1
公开(公告)日：2017-01-05
申请号：US15105328
申请日：2014-12-19
发明人： Christian HURTEVENT , Salima BARAKA-LOKMANE , John-Richard ORDONEZ-VARELA , Olivier TILLEMENT , Thomas BRICHART , Matteo MARTINI
CPC分类号： E21B37/06 , C09K8/528 , C09K8/54 , C09K2208/32 , E21B41/02 , E21B47/00 , E21B47/102
摘要： A method for adjusting, to a pre-determined value, the level of a mineral deposition or corrosion inhibitor injected into a gas or oil well. Using of the time-resolved fluorescence method for detecting and quantifying a mineral deposition or corrosion inhibitor in a fluid from an oil or gas production well.
摘要翻译： 调节注入气体或油井的矿物沉积或腐蚀抑制剂的水平的预定值的方法。 使用时间分辨荧光法检测和定量来自油气生产井的流体中的矿物沉积或腐蚀抑制剂。
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公开(公告)号：US20230173155A1
公开(公告)日：2023-06-08
申请号：US17997763
申请日：2021-04-30
申请人： MEXBRAIN , UNIVERSITE CLAUDE BERNARD LYON 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , INSTITUT GUSTAVE ROUSSY , VETAGRO-SUP INSTITUT D'ENSEIGNEMENT SUPÉRIEUR ET DE RECHERCHE
发明人： Marco NATUZZI , Thomas BRICHART , Fabien ROSSETTI , Matteo MARTINI , François LUX , Olivier TILLEMENT , Jean-Luc PERFETTINI , Vanessa LOUZIER , Jeanne-Marie BONNET-GARIN , Jean-Yves AYOUB
IPC分类号： A61M1/16
CPC分类号： A61M1/1621 , A61M1/1654
摘要： The present invention relates to the field of medical devices, more particularly the field of devices for extracting circulating molecules from the blood of a mammal, and their therapeutic uses, in particular in treating sepsis, cytokine release syndrome and/or any other form of systemic inflammatory response or cytokine shock, caused by bacterial, parasitic, fungal or viral infections, in particular caused by a viral infection, for example coronaviruses with human respiratory tract tropism.
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公开(公告)号：US20230346971A1
公开(公告)日：2023-11-02
申请号：US18253694
申请日：2021-11-19
申请人： NH THERAGUIX , UNIVERSITE CLAUDE BERNARD LYON 1 , MEXBRAIN , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - , INSERM (Institut National de la Santé et de la Recherche Médicale) , HOSPICES CIVILS DE LYON , INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
发明人： Olivier TILLEMENT , François LUX , Delphine VERNOS , Claire RODRIGUEZ-LAFRASSE , Thomas BRICHART , Marco NATUZZI , Alain GELOEN , Simon CHAMPAGNE , Matteo MARTINI , Paul ROCCHI
CPC分类号： A61K47/6935 , A61K9/08 , A61P35/00 , A61N5/10 , A61N2005/1098
摘要： The present disclosure relates to nanoparticles and the uses thereof in medicine, in particular for the treatment of tumours.
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5.发明公开公开(公告)号：US20230263912A1
公开(公告)日：2023-08-24
申请号：US18007254
申请日：2021-07-29
申请人： MEXBRAIN , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS , UNIVERSITE CLAUDE BERNARD LYON 1
发明人： Olivier TILLEMENT , François LUX , Fabien ROSSETTI , Marco NATUZZI , Thomas BRICHART , Laurent DAVID , Paula NUNES DE OLIVEIRA , Alexandra MONTEBAULT
CPC分类号： A61K49/128 , C08B37/003
摘要： The invention relates to a statistical polysaccharide with a weight-average molecular weight of between 100 kDa and 1000 kDa of the following formula (I): in which: each Rc independently represents a group containing a chelating agent, each Z independently represents a binder which may be a single bond or a hydrocarbon chain containing between 1 and 12 carbon atoms, said chain able to be either linear or branched and being able to contain one or more unsaturations and being able to contain one or more heteroatoms, preferably chosen from nitrogen, oxygen, sulfur and atoms of the halogen family, x is between 0.005 and 0.7, preferably between 0.05 and 0.7, and preferentially between 0.2 and 0.6, y is between 0.01 and 0.7, preferably between 0.05 and 0.2, the ratio of y/x being greater than or equal to 0.05, preferably greater than or equal to 0.15, and the sum of x+y being greater than or equal to 0.30, preferably greater than or equal to 0.35. The invention also relates to the use of said polysaccharide in a dialysis process in order to capture at least one metal, in an MRI imaging process, in a brachytherapy process or in a process for marking foodstuffs to prevent forgeries.
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公开(公告)号：US20220118164A1
公开(公告)日：2022-04-21
申请号：US17425147
申请日：2020-01-24
申请人： MEXBRAIN , UNIVERSITE CLAUDE BERNARD LYON 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS
发明人： Olivier TILLEMENT , François LUX , Marie VICTOR , Denise BECHET , Marco NATUZZI , Jules Tillement , Thomas BRICHART
摘要： The invention concerns the field of medical devices, more particularly devices for joint extraction, within an organism, of at least one metal cation and at least one target molecule. In order to do this, the device comprises: a) at least one ligand exhibiting specific affinity for the target molecule; b) at least one means for extraction of the metal cation, said means being a perfusion fluid comprising at least one chelating agent, the perfusion fluid being contained in a dialysis or microdialysis system. The use of these devices makes it possible, for example, to prevent and/or treat pathologies linked to dysregulation of the homeostasis of metals and/or target molecules in the organism, for example neurological diseases and/or proteinopathies.
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公开(公告)号：US20210205213A1
公开(公告)日：2021-07-08
申请号：US16955923
申请日：2018-12-21
申请人： MEXBRAIN , UNIVERSITE CLAUDE BERNARD LYON 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -
IPC分类号： A61K9/00 , A61M1/16 , A61K9/51 , A61K31/395
摘要： The present invention relates to the field of medical devices, more particularly to devices for extracting metals from an organism. The use of these devices makes it possible, for example, to prevent and/or treat pathologies linked to dysregulation of metal homeostasis in the organism, for example neurological diseases.
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