-
公开(公告)号：US11384385B2
公开(公告)日：2022-07-12
申请号：US16624469
申请日：2018-06-22
IPC分类号： C12Q1/6827 , C12Q1/6876
摘要： A therapeutic effect of irinotecan is predicted using a predetermined genetic polymorphism. A genetic polymorphism identified by rs1980576 in APCDD1L gene, or a genetic polymorphism in linkage disequilibrium with the above genetic polymorphism is analyzed, and determination is performed based on the genotype of the genetic polymorphism.
-
公开(公告)号：US11111526B2
公开(公告)日：2021-09-07
申请号：US16322363
申请日：2017-08-02
发明人： Toshiya Tsuda , Shuichi Kamei , Mitsuyoshi Oba , Hirofumi Yamano , Ryouichi Tsunedomi , Shoichi Hazama , Hiroaki Nagano
IPC分类号： C12Q1/68 , C12Q1/6832 , C07H21/00 , C12N15/09 , C12M1/00
摘要： In the case of using a blocking nucleic acid to prevent non-specific hybridization of a target nucleic acid with a nucleic acid probe, further excellent efficiency of detecting the target nucleic acid is achieved. A buffer composition used in hybridization of a target nucleic acid with a nucleic acid probe, wherein the buffer composition for hybridization contains a blocking nucleic acid comprising a nucleotide sequence complementary to a region comprising at least a non-detection target nucleotide in a non-target nucleic acid, in a concentration of one or more times higher than the concentration of a nucleic acid in a nucleic acid mixture consisting of the target nucleic acid and the non-target nucleic acid.
-
搜索结果
2 条记录 (耗时 0.013 秒)
