公开(公告)号：US06878689B2

公开(公告)日：2005-04-12

申请号：US10312484

申请日：2001-06-25

申请人： Takahiko Murata ,  Haruyoshi Ueo ,  Tadashi Ohyama

发明人： Takahiko Murata ,  Haruyoshi Ueo ,  Tadashi Ohyama

IPC分类号： A61K38/08 ,  A61P9/04

CPC分类号： A61K38/08

摘要： Preparations for preventing or treating acute heart failure, chronic heart failure at a phase of acute exacerbation or heart failure at a phase of transition to chronic heart failure, which contain D-alanyl-3-(naphthalen-2-yl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide and/or salts thereof as an active ingredient.

摘要翻译： 预防或治疗急性心力衰竭的准备，在急性加重阶段的慢性心力衰竭或在慢性心力衰竭过渡阶段的心力衰竭的制剂，其含有D-丙氨酰基-3-（萘-2-基）-D-丙氨酰 -L-丙氨酰-L-色氨酰-D-苯丙氨酰-L-赖氨酰胺和/或其盐作为活性成分。

公开(公告)号：US20110059176A1

公开(公告)日：2011-03-10

申请号：US12744251

申请日：2008-11-14

申请人： Toru Moro ,  Kozo Nakamura ,  Hiroshi Kawaguchi ,  Noriyuki Ishiyama ,  Kazuhiko Ishihara ,  Tomohiro Konno ,  Tadashi Ohyama ,  Mizuna Yoshikawa

发明人： Toru Moro ,  Kozo Nakamura ,  Hiroshi Kawaguchi ,  Noriyuki Ishiyama ,  Kazuhiko Ishihara ,  Tomohiro Konno ,  Tadashi Ohyama ,  Mizuna Yoshikawa

IPC分类号： A61K9/14 ,  A61P41/00 ,  A61K31/785

CPC分类号： A61K31/715 ,  A61K31/765 ,  A61K31/80

摘要： The present invention provides a tissue adhesion prevention material preparable at an affected area at the time of surgical procedure by producing a three-dimensional polymeric structure having a flexible structure and high solute permeability in a medium comprising water as the main component under mild conditions appropriate for body tissue components (i.e., at ordinary temperature and pressure) without conducting a chemical reaction or employing a physical procedure such as heating or light or radiation irradiation. This makes it possible to provide a tissue adhesion prevention material and a joint contracture prevention materials, which can effectively prevent postoperative adhesion of a tissue in the affected area to the surrounding tissue and contracture of the movable part of a joint.The tissue adhesion prevention material and/or the joint contracture prevention material of the present invention comprise, as the main component, a composition comprising a compound having a polyvalent hydroxyl group and a polymer containing phosphorylcholine groups and phenylboronic acid groups.

摘要翻译： 本发明提供了一种在外科手术时可以在患病区域制备的组织粘附防止材料，通过在适于温和条件的温和条件下，在包含水作为主要成分的介质中制备具有柔性结构和高溶质渗透性的三维聚合物结构 身体组织成分（即，在常温和常压下）而不进行化学反应或采用诸如加热或光或辐射照射的物理过程。 这使得可以提供能够有效地防止受影响的区域中的组织对周围组织的术后粘附和关节的可动部的挛缩的组织粘合防止材料和接合挛缩防止材料。 本发明的组织粘附防止材料和/或接合挛缩防止材料以包含具有多价羟基的化合物和含有磷酸胆碱基团的聚合物和苯基硼酸基的组成为主要成分。

公开(公告)号：US4442998A

公开(公告)日：1984-04-17

申请号：US424612

申请日：1982-09-27

申请人： Tadashi Ohyama ,  Shoji Kawata

发明人： Tadashi Ohyama ,  Shoji Kawata

IPC分类号： F16K11/044 ,  F16K31/06 ,  F16K31/02

CPC分类号： F16K31/0627 ,  F16K11/044 ,  H01F7/13 ,  H01F7/1607 ,  Y10T137/86895

摘要： In combination with a flow control valve assembly, an electromagnetic motor assembly includes a stationary core surrounded by a solenoid coil at its small diameter portion, a yoke member coaxially spaced from the stationary core and having an axial hole coaxial with the small diameter portion of the stationary core, and a movable core arranged between the stationary core and the yoke member. The stationary core is formed at its inner end with an annular recess, and the movable core is at its inner end with an annular projection to be coupled within the recess with a predetermined clearance.

摘要翻译： 结合流量控制阀组件，电磁马达组件包括由螺线管线圈在其小直径部分包围的固定芯部，与固定芯部同轴间隔的轭构件，并且具有与该直径部分的小直径部分同轴的轴向孔 固定铁芯和设置在固定铁芯和轭铁构件之间的可动铁芯。 固定芯在其内端处形成有环形凹部，并且可动芯在其内端处具有以预定间隙联接在凹部内的环形突起。

公开(公告)号：US06849597B2

公开(公告)日：2005-02-01

申请号：US10169423

申请日：2000-12-28

申请人： Takahiko Murata ,  Tadashi Ohyama ,  Masahiro Amakawa ,  Keiko Fujita ,  Haruyoshi Ueo

发明人： Takahiko Murata ,  Tadashi Ohyama ,  Masahiro Amakawa ,  Keiko Fujita ,  Haruyoshi Ueo

IPC分类号： A61K31/00 ,  A61K31/395 ,  A61K31/438 ,  A61K31/505 ,  A61K31/517 ,  A61K38/04 ,  A61K38/08 ,  A61K38/25 ,  A61P9/10 ,  A61P25/00 ,  A61P25/28 ,  C07D207/16 ,  C07D211/60 ,  C07D225/08 ,  C07D233/54 ,  C07D239/91 ,  C07D471/04 ,  C07D471/10 ,  A61K38/16 ,  C07K38/02

CPC分类号： C07D233/64 ,  A61K31/00 ,  A61K31/395 ,  A61K31/438 ,  A61K31/505 ,  A61K31/517 ,  A61K38/04 ,  A61K38/08 ,  A61K38/25 ,  C07D207/16 ,  C07D211/60 ,  C07D225/08 ,  C07D239/91 ,  C07D471/04 ,  C07D471/10 ,  Y10S930/12

摘要： An agent for prevention or treatment of diseases involving degeneration or death of nerve cells, characterized by containing a growth hormone secretion promoting substance as an active ingredient, is provided.

摘要翻译： 提供了一种用于预防或治疗涉及神经细胞变性或死亡的疾病的药剂，其特征在于含有生长激素分泌促进物质作为活性成分。

公开(公告)号：US4493474A

公开(公告)日：1985-01-15

申请号：US370269

申请日：1982-04-20

申请人： Tadashi Ohyama

发明人： Tadashi Ohyama

IPC分类号： F16K31/06 ,  H01F7/16

CPC分类号： F16K31/0655 ,  H01F7/1607 ,  H01F2007/163

摘要： An electromagnetic valve unit wherein a solenoid coil is assembled within a motor housing in surrounding relationship with a stationary core, a yoke member is fitted at its outer periphery to the corresponding fitting faces of the motor housing and a valve housing, a spring-loaded shaft is slidably supported by a pair of bearings in the stationary core and the yoke member for axial movement, and a movable core is fixed to the shaft to be moved between the stationary core and the yoke member. In such arrangement, a sleeve member of non-magnetic material is coupled over the stationary core and a stepped portion of the yoke member for alignment of the spaced bearings, and the yoke member has an annular shoulder coupled within the valve housing for alignment of the shaft in relation to a valve seat member which is assembled within the valve housing to cooperate with a valve element on the shaft.

摘要翻译： 一种电磁阀装置，其中螺线管线圈与电动机壳体组装在一个与固定铁芯相关的关系中，轭铁件的外周装配到电动机壳体的相应装配面和阀壳体上，一个弹簧加载轴 由固定铁芯中的一对轴承和用于轴向运动的轭构件可滑动地支撑，并且可动铁芯固定在轴上以在固定铁芯与轭铁构件之间移动。 在这种布置中，非磁性材料的套筒构件联接在固定铁芯和轭构件的阶梯部分上，用于对准间隔开的轴承，并且轭构件具有联接在阀壳体内的环形肩部，用于对准 轴相对于阀座构件组装在阀壳体内，以与轴上的阀元件配合。