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    Injectable drug carrier comprising layered double hydroxide
    1.
    发明授权
    Injectable drug carrier comprising layered double hydroxide 有权
    包含层状双氢氧化物的可注射药物载体

    公开(公告)号：US09017719B2

    公开(公告)日：2015-04-28

    申请号：US13541413

    申请日：2012-07-03

    申请人： Taeun Park ,  Jin-Ho Choy ,  Jae-Min Oh ,  Ji-Sun Jung

    发明人： Taeun Park ,  Jin-Ho Choy ,  Jae-Min Oh ,  Ji-Sun Jung

    IPC分类号： A61K9/127 ,  A61K9/00 ,  A61K9/14 ,  A61K47/02

    CPC分类号： A61K9/0019 ,  A61K9/143 ,  A61K47/02

    摘要： Provided is an injectable drug carrier including a non-toxic Layered Double Hydroxide (LDH) and pharmaceutically acceptable excipients. Provided is also a method of preparing the injectable drug carrier, the method including: synthesizing LDH with various compositions and controlling the size and shape of the LDH at a level that the LDH has no adverse effect in vivo. A solution obtained by dispersing the LDH in a solvent is injected in vivo. According to the method, nano-size LDH that does not affect a blood vessel in vivo can be synthesized. The LDH thus synthesized has no adverse effect in vivo even at a concentration of 400 mg/kg, and thus can contribute to establishment of a drug delivery system capable of improving the delivery efficiency of a specific drug.

    摘要翻译： 提供了包含无毒层状双氢氧化物（LDH）和药学上可接受的赋形剂的可注射药物载体。 还提供了一种制备可注射药物载体的方法，该方法包括：以各种组成合成LDH，并以LDH在体内没有不利影响的水平控制LDH的大小和形状。 将LDH分散在溶剂中得到的溶液体内注射。 根据该方法，可以合成不影响体内血管的纳米级LDH。 如此合成的LDH即使在400mg / kg的浓度下也不会在体内产生不利影响，因此有助于建立能够提高特定药物的输送效率的药物输送系统。

    INJECTABLE DRUG CARRIER COMPRISING LAYERED DOUBLE HYDROXIDE
    2.
    发明申请
    INJECTABLE DRUG CARRIER COMPRISING LAYERED DOUBLE HYDROXIDE 审中-公开
    包含层状双氢氧化物的注射式药物载体

    公开(公告)号：US20100047307A1

    公开(公告)日：2010-02-25

    申请号：US11915922

    申请日：2005-06-03

    申请人： Taeun Park ,  Jin-ho Choy ,  Jae-Min Oh ,  Ji-Sun Jung

    发明人： Taeun Park ,  Jin-ho Choy ,  Jae-Min Oh ,  Ji-Sun Jung

    IPC分类号： A61K9/14 ,  A61K31/519 ,  A61P35/00 ,  A61P37/02

    CPC分类号： A61K9/0019 ,  A61K9/143 ,  A61K47/02

    摘要： Provided is an injectable drug carrier including a non-toxic Layered Double Hydroxide (LDH) and pharmaceutically acceptable excipients. Provided is also a method of preparing the injectable drug carrier, the method including: synthesizing LDH with various compositions and controlling the size and shape of the LDH at a level that the LDH has no adverse effect in vivo. A solution obtained by dispersing the LDH in a solvent is injected in vivo. According to the method, nano-size LDH that does not affect a blood vessel in vivo can be synthesized. The LDH thus synthesized has no adverse effect in vivo even at a concentration of 400 mg/kg, and thus can contribute to establishment of a drug delivery system capable of improving the delivery efficiency of a specific drug.

    摘要翻译： 提供了包含无毒层状双氢氧化物（LDH）和药学上可接受的赋形剂的可注射药物载体。 还提供了一种制备可注射药物载体的方法，该方法包括：以各种组成合成LDH，并以LDH在体内没有不利影响的水平控制LDH的大小和形状。 将LDH分散在溶剂中得到的溶液体内注射。 根据该方法，可以合成不影响体内血管的纳米级LDH。 如此合成的LDH即使在400mg / kg的浓度下也不会在体内产生不利影响，因此有助于建立能够提高特定药物的输送效率的药物输送系统。

    Information Code System Using Dna Sequences
    3.
    发明申请
    Information Code System Using Dna Sequences 审中-公开
    使用Dna序列的信息代码系统

    公开(公告)号：US20080268431A1

    公开(公告)日：2008-10-30

    申请号：US11575252

    申请日：2004-09-14

    申请人： Jin-Ho Choy ,  Man Park ,  Jae-Min Oh

    发明人： Jin-Ho Choy ,  Man Park ,  Jae-Min Oh

    IPC分类号： C12Q1/68 ,  C07H21/00

    CPC分类号： B82Y5/00 ,  C12Q1/68 ,  C12Q2563/185

    摘要： The present invention provides a molecular level of DNA information code which uses a base pair sequence as an information code unit. Also, the present invention provides a molecular code system which includes designing and coding DNA which is an information code unit; stabilizing the DNA information code by encapsulating it with an inorganic capsule and coating the DNA-inorganic capsule to a medium; taking and extracting the coated DNA information code which is present in a trace amount, collecting the DNA information code using a polypyrrole-maghemite nanohybrid; and amplifying the collected DNA information code using a polymerase chain reaction and reading the amplified DNA information code. According to the present invention, the DNA information code having high security is prepared by assigning a security unit to a DNA which has an excellent accumulating capacity, and then the DNA information code is stabilized so as to be coated to a medium. Only the DNA information code may be extracted, collected, and read, if necessary. Thus, a unified molecular code system can be established.

    摘要翻译： 本发明提供了使用碱基对序列作为信息代码单元的DNA信息码的分子水平。 另外，本发明提供了一种分子代码系统，其包括设计和编码作为信息代码单元的DNA; 通过用无机胶囊包封DNA并将DNA-无机胶囊包被在培养基中来稳定DNA信息代码; 采取和提取微量存在的涂层DNA信息代码，使用聚吡咯 - 磁赤铁矿纳米杂交物收集DNA信息代码; 并使用聚合酶链反应扩增收集的DNA信息码并读取扩增的DNA信息码。 根据本发明，具有高安全性的DNA信息码通过将安全性单位分配给具有优异的累积能力的DNA，然后将DNA信息码稳定化，从而涂布到介质上。 必要时，只能提取，收集和阅读DNA信息代码。 因此，可以建立统一的分子代码系统。

    Liquid crystal photo-alignment agent and liquid crystal photo-alignment film and liquid crystal display including the same
    4.
    发明授权
    Liquid crystal photo-alignment agent and liquid crystal photo-alignment film and liquid crystal display including the same 有权
    液晶光取向剂和液晶光取向膜以及包括其的液晶显示器

    公开(公告)号：US08057700B2

    公开(公告)日：2011-11-15

    申请号：US12329139

    申请日：2008-12-05

    申请人： Jae-Min Oh ,  Dong-Seon Uh ,  Jae-Deuk Yang ,  Tae-Hyoung Kwak

    发明人： Jae-Min Oh ,  Dong-Seon Uh ,  Jae-Deuk Yang ,  Tae-Hyoung Kwak

    IPC分类号： C09K19/56 ,  G02F1/1337

    CPC分类号： G02F1/133723 ,  C09K19/56 ,  G02F1/133788 ,  Y10T428/1005 ,  Y10T428/1018 ,  Y10T428/1023

    摘要： One embodiment of the present invention provides a liquid crystal photo-alignment agent that includes a polyamic acid copolymer including a repeating unit having the following Formula 1 and a repeating unit having the following Formula 2; a polyimide copolymer including a repeating unit having the following Formula 3 and a repeating unit having the following Formula 4; or a combination thereof: wherein the definition of R1 to R8 are the same as in the specification. The liquid crystal photo-alignment agent can have improved liquid crystal alignment properties, electrical characteristics such as voltage holding ratio, pretilt angle, residual DC, and the like, printability, cleaning stability, and spot stability, and is capable of unidirectionally aligning liquid crystals by ultraviolet (UV) exposure.

    摘要翻译： 本发明的一个实施方案提供一种液晶光取向剂，其包括含有具有下式1的重复单元和具有下式2的重复单元的聚酰胺酸共聚物; 包含具有下式3的重复单元和具有下式4的重复单元的聚酰亚胺共聚物; 或其组合：其中R1至R8的定义与说明书中的相同。 液晶光取向剂可以具有改善的液晶取向性，电压保持率，预倾角，残留DC等的电特性，可印刷性，清洁稳定性和光斑稳定性，并且能够将液晶 通过紫外线（UV）曝光。

    Soluble polyimide resin for liquid crystal alignment layer and process of preparation of the same
    7.
    发明授权
    Soluble polyimide resin for liquid crystal alignment layer and process of preparation of the same 失效
    用于液晶取向层的可溶性聚酰亚胺树脂及其制备方法

    公开(公告)号：US6013760A

    公开(公告)日：2000-01-11

    申请号：US86385

    申请日：1998-05-29

    申请人： Kil-Yeong Choi ,  Mi-Hie Yi ,  Moon-Young Jin ,  Dae-Woo Ihm ,  Jae-Min Oh

    发明人： Kil-Yeong Choi ,  Mi-Hie Yi ,  Moon-Young Jin ,  Dae-Woo Ihm ,  Jae-Min Oh

    IPC分类号： C08G73/10 ,  G02F1/1337 ,  C08G69/28

    CPC分类号： C08G73/10 ,  G02F1/133723 ,  Y10T428/31721

    摘要： The invention herein relates to a soluble polyimide resin for a liquid crystal alignment layer and the process of preparation of the same, wherein aliphatic tetracarboxylic dianhydride and aromatic diamine having the amide group are used to yield a novel form of a polyimide resin having superior heat-resistance, solubility, transparency, and liquid crystal alignment capacity.More specifically, the invention herein relates to a novel polyimide resin having excellent heat-resistance, solubility, liquid crystal alignment property, and high pretilt angle, which is prepared by means of jointly using the aromatic diamine, used for the preparation of the conventional polyimide resin, and the aromatic diamine having a long alkyl chain with a substituted amide group, and reacting the same with various types of carboxylic dianhydride.

    摘要翻译： 本发明涉及用于液晶取向层的可溶性聚酰亚胺树脂及其制备方法，其中使用具有酰胺基的脂族四羧酸二酐和芳族二胺以产生具有优异的耐热性的聚酰亚胺树脂的新型， 电阻，溶解度，透明度和液晶取向能力。 更具体地说，本发明涉及一种新型的聚酰亚胺树脂，其具有优异的耐热性，溶解性，液晶取向性和高预倾角，这是通过共同使用芳族二胺制备的，用于制备常规聚酰亚胺 树脂和具有取代酰胺基的长烷基链的芳族二胺，并使其与各种羧酸二酐反应。