公开(公告)号：US5886654A

公开(公告)日：1999-03-23

申请号：US901290

申请日：1997-07-31

申请人： Takahiro Ichikawa ,  Kazuhiro Yasuda ,  Tadashi Nakata ,  Shigeharu Sato

发明人： Takahiro Ichikawa ,  Kazuhiro Yasuda ,  Tadashi Nakata ,  Shigeharu Sato

IPC分类号： G11B20/18 ,  H03M13/00

CPC分类号： G11B20/1833 ,  G11B20/1876

摘要： Decoding apparatus and method set interpolation flags in units smaller than an ECC block. The PI1 flag indicating an error on a row-by-row basis is generated for the first error correction result, while the PI2 flag also indicating an error on a row-by-row basis is generated for the second error correction result in the ECC block. The PO flag indicating an error on a column-by-column basis is further generated for the error correction result in the ECC block. Following these processing operations, the PI1, PI2 and PO flags are used for generating the interpolation flags.

摘要翻译： 解码装置和方法以小于ECC块的单位设置内插标志。 针对第一纠错结果产生指示逐行的错误的PI1标志，同时针对逐行依次指示错误的PI2标志产生ECC中的第二纠错结果 块。 针对ECC块中的纠错结果进一步生成指示逐列的错误的PO标志。 在这些处理操作之后，PI1，PI2和PO标志用于产生内插标志。

公开(公告)号：US5710143A

公开(公告)日：1998-01-20

申请号：US615299

申请日：1996-03-27

申请人： Kunio Suzuki ,  Tadashi Nakata ,  Takeshi Shimizu ,  Kotaro Enomoto

发明人： Kunio Suzuki ,  Tadashi Nakata ,  Takeshi Shimizu ,  Kotaro Enomoto

IPC分类号： A23L33/20 ,  A61K31/575 ,  A61P3/04 ,  C07J9/00

CPC分类号： A61K31/575

摘要： Disclosed are anti-obesity agents comprising 3-ketosteroidal compounds as defined in the specification. The present invention also discloses pharmaceutical compositions and use of these compounds in the prevention and treatment of obesity.

摘要翻译： PCT No.PCT / JP94 / 01631 Sec。 371日期：1996年3月27日 102（e）1996年3月27日PCT 1994年9月30日PCT公布。 公开号WO95 / 08995 日期1995年4月6日公开是包含说明书中定义的3-酮甾烷化合物的抗肥胖剂。 本发明还公开了药物组合物和这些化合物在预防和治疗肥胖症中的用途。

公开(公告)号：US20060173069A1

公开(公告)日：2006-08-03

申请号：US10564367

申请日：2004-07-15

申请人： Hiroyuki Osada ,  Kiyotaka Machida ,  Takeshi Shimizu ,  Tadashi Nakata ,  Toshimasa Shinki ,  Je-Tae Woo ,  Kazuo Nagai

发明人： Hiroyuki Osada ,  Kiyotaka Machida ,  Takeshi Shimizu ,  Tadashi Nakata ,  Toshimasa Shinki ,  Je-Tae Woo ,  Kazuo Nagai

IPC分类号： A61K31/695 ,  A61K31/353 ,  C07F7/02

CPC分类号： C07D493/10 ,  Y02P20/55

摘要： The present invention has an object to provide a novel therapeutic agent for hypercalcemia and bone diseases, and a novel compound capable of being used as an active ingredient of the therapeutic agent. The present invention is a therapeutic agent for hypercalcemia or bone diseases, comprising as an active ingredient a reveromycin A derivative represented by the general formula (I) or a pharmaceutically acceptable salt thereof. (R represents a hydroxyl-protecting group releasable under acidic conditions.)

摘要翻译： 本发明的目的是提供一种用于高钙血症和骨疾病的新型治疗剂，以及能够用作治疗剂的活性成分的新型化合物。 本发明是高钙血症或骨疾病的治疗剂，其含有作为活性成分的由通式（I）表示的复方霉素A衍生物或其药学上可接受的盐。 （R表示在酸性条件下可释放的羟基保护基）

公开(公告)号：US06839634B1

公开(公告)日：2005-01-04

申请号：US09266813

申请日：1999-03-12

申请人： Hiroko Satoh ,  Kimito Funatsu ,  Tadashi Nakata ,  Keiko Takano

发明人： Hiroko Satoh ,  Kimito Funatsu ,  Tadashi Nakata ,  Keiko Takano

IPC分类号： G06G7/48 ,  G01Q33/48 ,  G06F101/00 ,  G01Q33/50

CPC分类号： G06F19/702

摘要： A molecule surrounding surface (20) is set so as to be reflected in the spatial dimension of a molecule. A molecule surrounding space surrounded by the molecule surrounding surface is divided into a plurality of component spaces (22), by which the reaction characteristic of the molecule is characterized. Probe points are provided on a frontier surrounding surface (5) on the molecule surrounding surface, and a space occupied rate is derived for each of the component spaces. Electrostatic energies are derived for each of the probe points on the frontier surrounding surface, and the sum of the electrostatic energies on the frontier surrounding surface is derived as a enelectrostatic factor of each of the component spaces. In addition, van der Waals energies are derived for each of the probe points, and the sum of the van der Waals energies on the frontier surrounding surface is derived as a steric factor of each of the component spaces. Assuming that the space occupied rate, the electrostatic factor and the steric factor are reaction characteristic values of the corresponding one of the component spaces, the reaction characteristic of the molecule is predicted on the basis of the reaction characteristic values of each of the component spaces.

公开(公告)号：US5846962A

公开(公告)日：1998-12-08

申请号：US897884

申请日：1997-07-21

申请人： Kunio Suzuki ,  Tadashi Nakata ,  Takeshi Shimizu ,  Kotaro Enomoto

发明人： Kunio Suzuki ,  Tadashi Nakata ,  Takeshi Shimizu ,  Kotaro Enomoto

IPC分类号： A23L33/20 ,  A61K31/575 ,  A61P3/04 ,  C07J9/00

CPC分类号： A61K31/575

摘要： Anti-obesity agents which comprise 3-ketosteroid compounds as an active ingredient are provided. The anti-obesity agents of the present invention have a high anti-obesity effect with little or no side effects and toxicity. Food products which contain anti-obesity agents comprising 3-ketosteroid compounds as an active ingredient, pharmaceutical compositions which comprise 3-ketosteroid compounds as an active ingredient and pharmaceutically acceptable carriers, and methods for preventing and treating obesity which comprise administering an effective amount of a 3-ketosteroid compound to a human are also provided.

摘要翻译： 提供了包含3-酮类固醇化合物作为活性成分的抗肥胖剂。 本发明的抗肥胖剂具有很高的抗肥胖作用，很少或没有副作用和毒性。 含有3-酮类固醇化合物作为活性成分的抗肥胖剂的食品，包含3-酮类固醇化合物作为活性成分的药物组合物和药学上可接受的载体，以及预防和治疗肥胖症的方法，其包括施用有效量的 还提供了3-酮类固醇化合物给人类。

公开(公告)号：US07306834B2

公开(公告)日：2007-12-11

申请号：US10258522

申请日：2001-04-26

申请人： Akira Nonomura ,  Masaaki Suzuki ,  Atsushi Sato ,  Tadashi Nakata ,  Shinji Kodama ,  Shingo Odajima ,  Mitsuyuki Kubo

发明人： Akira Nonomura ,  Masaaki Suzuki ,  Atsushi Sato ,  Tadashi Nakata ,  Shinji Kodama ,  Shingo Odajima ,  Mitsuyuki Kubo

IPC分类号： B29D27/00 ,  B29D23/00 ,  B32B1/08 ,  B32B27/10

CPC分类号： B65D81/3874 ,  B32B1/02 ,  B32B5/26 ,  B32B7/02 ,  D21J3/10 ,  D21J5/00 ,  Y10T428/1303 ,  Y10T428/2495 ,  Y10T428/24992

摘要： A heat-insulating container having a first fiber layer (111) with a prescribed density and a second fiber layer (112) which is formed inside the first fiber layer (111) and has a lower density than the first fiber layer (111). The first fiber layer (111) is 0.2 to 1 mm thick, and the second fiber layer (112) is 0.4 to 3 mm thick, with the total thickness of the first fiber layer (111) and the second fiber layer (112) being 0.6 to 4 mm.

摘要翻译： 一种具有规定密度的第一纤维层（111）和形成在第一纤维层（111）内部并具有比第一纤维层（111）低的密度的第二纤维层（112）的绝热容器。 第一纤维层（111）的厚度为0.2〜1mm，第二纤维层（112）的厚度为0.4〜3mm，第一纤维层（111）和第二纤维层（112）的总厚度为 0.6至4毫米。

公开(公告)号：US06531462B2

公开(公告)日：2003-03-11

申请号：US10036474

申请日：2002-01-07

申请人： Kunio Suzuki ,  Takeshi Shimizu ,  Tadashi Nakata

发明人： Kunio Suzuki ,  Takeshi Shimizu ,  Tadashi Nakata

IPC分类号： A61K3156

CPC分类号： A61K31/575

摘要： A medicament for preventive and therapeutic treatment of obesity and a disease with abnormal lipid metabolism which comprises a 24-alkylcholest-5-en-3-one as an active ingredient.

公开(公告)号：US6046184A

公开(公告)日：2000-04-04

申请号：US186158

申请日：1998-11-05

申请人： Kunio Suzuki ,  Takeshi Shimizu ,  Tadashi Nakata

发明人： Kunio Suzuki ,  Takeshi Shimizu ,  Tadashi Nakata

IPC分类号： A23K1/18 ,  A23K1/16 ,  A23L1/30 ,  A61K31/575 ,  A61P3/04 ,  A61P3/06 ,  C07J9/00 ,  A61K31/56

CPC分类号： A61K31/575 ,  Y10S514/824 ,  Y10S514/909

摘要： A medicament for preventive and therapeutic treatment of obesity and a disease with abnormal lipid metabolism which comprises as an active ingredient a compound selected from the group consisting of 24-alkylcholestan-3-ones and 24-alkylcholesten-3-ones such as 24-alkylcholestan-3-ones, 24-alkylcholestmonoen-3-ones, 24-alkylcholestdien-3-ones, 24-alkylcholesttrien-3-ones and 24-alkylcholesttetraen-3-ones.

摘要翻译： 一种用于预防和治疗肥胖症和脂代谢异常的疾病的药物，其包含作为活性成分的选自24-烷基胆甾烷-3-酮和24-烷基胆甾烯-3-酮的化合物，例如24-烷基胆甾烷 4-烷基胆甾烯-3-酮，24-烷基胆甾烯-3-酮，24-烷基胆甾烯-3-酮和24-烷基胆甾四烯-3-酮。

公开(公告)号：US5293368A

公开(公告)日：1994-03-08

申请号：US749110

申请日：1991-08-23

申请人： Tadashi Nakata

发明人： Tadashi Nakata

IPC分类号： G11B7/00 ,  G11B7/0045 ,  G11B7/005 ,  G11B20/10 ,  G11B27/19 ,  G11B27/30

CPC分类号： G11B27/19 ,  G11B20/10 ,  G11B27/3036 ,  G11B7/005

摘要： An apparatus for reproducing address data recorded on a disk record medium with an information signal which is recorded on the same by forming pit portions in response to the information signal included a pickup for optically reproducing the recorded data and signals is provided. Also the apparatus includes a circuit for generating a sampling pulse from the recorded data and signals so that the sampling pulse occurs substantially beginning position of a mirror portion beginning the pit portions, a circuit for sampling and holding the recorded data and signals by the sampling pulse, and a circuit for decoding an output signal of the sampling and holding means so as to generate the address data.

摘要翻译： 提供了一种用于通过响应于包括的信息信号形成凹坑部分来再现记录在其上的信息信号的记录在盘记录介质上的地址数据的装置，用于光学再现所记录的数据和信号的拾取器。 该装置还包括用于从记录的数据和信号产生采样脉冲的电路，使得采样脉冲基本上出现在开始凹坑部分的反射镜部分的开始位置，用于通过采样脉冲采样和保持所记录的数据和信号的电路 以及用于解码采样和保持装置的输出信号以产生地址数据的电路。