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公开(公告)号:US5758289A
公开(公告)日:1998-05-26
申请号:US488077
申请日:1995-06-07
申请人: Ronald Lee Lipp , Susumi Ohashi , Zhao Min , Hiroki Ohno , Kazuhiko Shimizu , Takahiro Kudo , Takashi Odagiri
发明人: Ronald Lee Lipp , Susumi Ohashi , Zhao Min , Hiroki Ohno , Kazuhiko Shimizu , Takahiro Kudo , Takashi Odagiri
CPC分类号: H04M1/725 , H04M1/6545 , H04M1/72502
摘要: A relay lifter comprises a hook switch unit for turning ON/OFF a hook switch in response to a talk switch, a voice switching unit for switching connection of an aural signal in said corded telephone set between a transmitter/receiver of said corded telephone set and a cordless telephone set, and a bell sound detection signal transfer unit, a bell sound is outputted from said cordless telephone set when a bell sound is detected and an incoming call is accepted, a hook switch is turned ON/OFF using a hook switch ON/OFF unit, and connection of an aural signal in said corded telephone set is switched to said cordless telephone set for transmitting and receiving voice using said cordless telephone set.
摘要翻译: 一个继电器升降器包括一个用于响应于一个通话开关来打开/关闭一个挂钩开关的挂钩开关单元,一个话音切换单元,用于在所述有线电话机的发送器/接收器之间切换所述有线电话机中的听觉信号的连接, 无绳电话机和铃声检测信号传送单元,当检测到铃声并接受来电时,从所述无绳电话机输出铃声,使用挂钩开关打开/关闭挂钩开关 / OFF单元,并且将所述有线电话机中的听觉信号的连接切换到用于使用所述无绳电话机发送和接收语音的所述无绳电话机。
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公开(公告)号:US5801466A
公开(公告)日:1998-09-01
申请号:US472236
申请日:1995-06-07
申请人: Takashi Odagiri , Hiroki Ohno
发明人: Takashi Odagiri , Hiroki Ohno
CPC分类号: G08B6/00 , H02K5/00 , H02K7/061 , Y10T74/18552
摘要: A motor 3 having a rotational shaft with a counterweight 4 is held in a vibrator holder 2. The rotational shaft of the motor is inserted at a free end in a circular hole in a bearing-plate of the vibrator holder 2. The vibrator holder 2 with the motor therein is accommodates in a vibrator accommodating section 120 formed in a housing 12 of a portable terminal and fixed with screws 5 to the housing 12. The vibrator holder 120 is then covered with an index cover 17 to thereby complete the vibrator attachment, which reduces a vibrator attaching work load. The inner wall of the vibrator accommodating section 120 faces the motor to thereby prevent the motor 3 from slipping from the holder.
摘要翻译: 将具有配重4的旋转轴的马达3保持在振动器保持器2中。马达的旋转轴在振动器保持器2的支承板中的圆形孔中的自由端插入。振动器保持器2 其中的电动机容纳在形成在便携式终端的壳体12中的振动器容纳部分120中,并用螺钉5固定到壳体12.然后,振动器保持器120被索引盖17覆盖,从而完成振动器附接, 这减少了振动器附着工作负荷。 振动器容纳部分120的内壁面对电动机,从而防止电动机3从保持器滑落。
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公开(公告)号:US5732355A
公开(公告)日:1998-03-24
申请号:US480770
申请日:1995-06-07
申请人: Ronald Lee Lipp , Susumi Ohashi , Atsushi Kaneda , Zhao Min , Hiroki Ohno , Kazuhiko Shimizu , Takahiro Kudo , Takashi Odagiri , Makoto Ehara
发明人: Ronald Lee Lipp , Susumi Ohashi , Atsushi Kaneda , Zhao Min , Hiroki Ohno , Kazuhiko Shimizu , Takahiro Kudo , Takashi Odagiri , Makoto Ehara
CPC分类号: H04M1/725 , H04M1/6545 , H04M1/72502
摘要: The is provided by the present invention a telephone system with high versatility comprising a corded telephone set, a cordless telephone set, and a relay lifter, wherein said relay lifter comprises a hook switch unit for turning ON/OFF a hook switch of the corded telephone set according to a first control signal responding to the talk switch, and a voice switching unit for switching connection of an aural signal in the corded telephone set according to a second control signal between a transmitter/receiver of the corded telephone set and the cordless telephone set, and switches connection of an aural signal in the corded telephone set to the cordless telephone set using the voice switching unit to transmit or receive voice using the cordless telephone set.
摘要翻译: 本发明提供了一种具有高通用性的电话系统,包括有线电话机,无绳电话机和继电器升降器,其中所述继电器升降器包括用于打开/关闭有线电话的挂钩开关的挂钩开关单元 根据响应于通话开关的第一控制信号设置的语音切换单元,用于根据第二控制信号在有线电话机的发送器/接收器与无绳电话机之间切换有线电话机中的听觉信号的连接的语音切换单元 使用语音切换单元将有线电话机中的听觉信号的连接切换到无绳电话机,以使用无绳电话机发送或接收语音。
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公开(公告)号:US08309546B2
公开(公告)日:2012-11-13
申请号:US13308239
申请日:2011-11-30
申请人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
发明人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
IPC分类号: A61K31/535 , C07D413/14
CPC分类号: C07D473/34
摘要: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.
摘要翻译: 提供抑制磷脂酰肌醇3-激酶(PI3K)和/或雷帕霉素(mTOR)的哺乳动物靶标并表现出抗肿瘤活性的新型化合物。 本发明提供具有抑制PI3K和/或mTOR的各种取代基并表现出抗肿瘤活性的下述式(1)表示的化合物:其中R1,R2,R3,R4,Ra,Rb,Rc和X各自具有 与本说明书中定义的含义相同。
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公开(公告)号:US20120108582A1
公开(公告)日:2012-05-03
申请号:US12459612
申请日:2009-07-02
申请人: Hisashi Takahashi , Satoshi Komoriya , Takahiro Kitamura , Takashi Odagiri , Hiroaki Inagaki , Toshifumi Tsuda , Kiyoshi Nakayama , Makoto Takemura , Kenichi Yoshida , Rie Miyauchi , Masatoshi Nagamochi
发明人: Hisashi Takahashi , Satoshi Komoriya , Takahiro Kitamura , Takashi Odagiri , Hiroaki Inagaki , Toshifumi Tsuda , Kiyoshi Nakayama , Makoto Takemura , Kenichi Yoshida , Rie Miyauchi , Masatoshi Nagamochi
IPC分类号: A61K31/4709 , C07D498/06 , A61K31/5383 , A61P1/12 , A61P29/00 , A61P31/04 , A61P31/00 , A61P33/00 , A61P17/00 , A61P15/00 , A61P17/10 , A61P11/08 , A61P11/00 , A61P13/08 , A61P13/02 , A61P27/02 , A61P1/02 , A61P37/00 , A61P31/06 , A61P31/08 , C07D401/10
CPC分类号: C07D498/06 , C07D209/02 , C07D209/56 , C07D401/04 , C07D401/14 , C07D491/048 , C07D491/052 , Y02P20/55
摘要: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.
摘要翻译: 提供了作为药物具有优异性能的喹诺酮合成抗菌剂,其不仅对革兰氏阴性菌具有很强的抗菌活性,而且对喹诺酮类抗菌剂具有低敏感性的革兰氏阳性球菌具有很强的抗菌活性,并且其表现出高安全性和优异的药代动力学 。 由式(I)表示的化合物或其盐或其水合物。 具体地,其中取代基R6和R7与它们所键合的碳原子一起形成式(I)的喹诺酮衍生物形成可以含有氧原子作为环组成原子的环状结构,所述环状结构形成5- 4,5,5-或5-6稠合双环吡咯烷基取代基,该取代基与含有吡啶并苯并恶嗪结构的喹诺酮母体骨架Q结合。
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公开(公告)号:US20100130492A1
公开(公告)日:2010-05-27
申请号:US12579175
申请日:2009-10-14
申请人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
发明人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
IPC分类号: A61K31/5377 , C07D487/04 , A61P43/00 , A61P35/00
CPC分类号: C07D473/34
摘要: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.
摘要翻译: 提供抑制磷脂酰肌醇3-激酶(PI3K)和/或雷帕霉素(mTOR)的哺乳动物靶标并表现出抗肿瘤活性的新型化合物。 本发明提供具有抑制PI3K和/或mTOR的各种取代基并表现出抗肿瘤活性的下述式(1)表示的化合物:其中R1,R2,R3,R4,Ra,Rb,Rc和X各自具有 与本说明书中定义的含义相同。
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公开(公告)号:US08618094B2
公开(公告)日:2013-12-31
申请号:US12459612
申请日:2009-07-02
申请人: Hisashi Takahashi , Satoshi Komoriya , Takahiro Kitamura , Takashi Odagiri , Hiroaki Inagaki , Toshifumi Tsuda , Kiyoshi Nakayama , Makoto Takemura , Kenichi Yoshida , Rie Miyauchi , Masatoshi Nagamochi
发明人: Hisashi Takahashi , Satoshi Komoriya , Takahiro Kitamura , Takashi Odagiri , Hiroaki Inagaki , Toshifumi Tsuda , Kiyoshi Nakayama , Makoto Takemura , Kenichi Yoshida , Rie Miyauchi , Masatoshi Nagamochi
IPC分类号: C07D401/10 , C07D498/06 , A61K31/4709 , A61K31/5383
CPC分类号: C07D498/06 , C07D209/02 , C07D209/56 , C07D401/04 , C07D401/14 , C07D491/048 , C07D491/052 , Y02P20/55
摘要: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.
摘要翻译: 提供了作为药物具有优异性能的喹诺酮合成抗菌剂,其不仅对革兰氏阴性菌具有很强的抗菌活性,而且对喹诺酮类抗菌剂具有低敏感性的革兰氏阳性球菌具有很强的抗菌活性,并且其表现出高安全性和优异的药代动力学 。 由式(I)表示的化合物或其盐或其水合物。 具体地,其中取代基R6和R7与它们所键合的碳原子一起形成式(I)的喹诺酮衍生物形成可以含有氧原子作为环组成原子的环状结构,所述环状结构形成5- 4,5,5-或5-6稠合双环吡咯烷基取代基,该取代基与含有吡啶并苯并恶嗪结构的喹诺酮母体骨架Q结合。
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公开(公告)号:US20130029977A9
公开(公告)日:2013-01-31
申请号:US12459612
申请日:2009-07-02
申请人: Hisashi Takahashi , Satoshi Komoriya , Takahiro Kitamura , Takashi Odagiri , Hiroaki Inagaki , Toshifumi Tsuda , Kiyoshi Nakayama , Makoto Takemura , Kenichi Yoshida , Rie Miyauchi , Masatoshi Nagamochi
发明人: Hisashi Takahashi , Satoshi Komoriya , Takahiro Kitamura , Takashi Odagiri , Hiroaki Inagaki , Toshifumi Tsuda , Kiyoshi Nakayama , Makoto Takemura , Kenichi Yoshida , Rie Miyauchi , Masatoshi Nagamochi
IPC分类号: A61K31/4709 , C07D498/06 , A61K31/5383 , A61P1/12 , A61P29/00 , A61P31/04 , A61P31/00 , A61P33/00 , A61P17/00 , A61P15/00 , A61P17/10 , A61P11/08 , A61P11/00 , A61P13/08 , A61P13/02 , A61P27/02 , A61P1/02 , A61P37/00 , A61P31/06 , A61P31/08 , C07D401/10
CPC分类号: C07D498/06 , C07D209/02 , C07D209/56 , C07D401/04 , C07D401/14 , C07D491/048 , C07D491/052 , Y02P20/55
摘要: A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.
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公开(公告)号:US08097622B2
公开(公告)日:2012-01-17
申请号:US12579175
申请日:2009-10-14
申请人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
发明人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
IPC分类号: A61K31/535 , C07D413/14
CPC分类号: C07D473/34
摘要: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.
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公开(公告)号:US20120071476A1
公开(公告)日:2012-03-22
申请号:US13308239
申请日:2011-11-30
申请人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
发明人: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
IPC分类号: A61K31/5377 , A61P35/00 , C07D413/14
CPC分类号: C07D473/34
摘要: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.
摘要翻译: 提供抑制磷脂酰肌醇3-激酶(PI3K)和/或雷帕霉素(mTOR)的哺乳动物靶标并表现出抗肿瘤活性的新型化合物。 本发明提供具有抑制PI3K和/或mTOR的各种取代基并表现出抗肿瘤活性的下述式(1)表示的化合物:其中R1,R2,R3,R4,Ra,Rb,Rc和X各自具有 与本说明书中定义的含义相同。
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