Morpholinopurine derivatives
    4.
    发明授权
    Morpholinopurine derivatives 有权
    吗啉嘌呤衍生物

    公开(公告)号:US08309546B2

    公开(公告)日:2012-11-13

    申请号:US13308239

    申请日:2011-11-30

    IPC分类号: A61K31/535 C07D413/14

    CPC分类号: C07D473/34

    摘要: There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.

    摘要翻译: 提供抑制磷脂酰肌醇3-激酶(PI3K)和/或雷帕霉素(mTOR)的哺乳动物靶标并表现出抗肿瘤活性的新型化合物。 本发明提供具有抑制PI3K和/或mTOR的各种取代基并表现出抗肿瘤活性的下述式(1)表示的化合物:其中R1,R2,R3,R4,Ra,Rb,Rc和X各自具有 与本说明书中定义的含义相同。

    Telephone system and bell sound detecting method thereof
    8.
    发明授权
    Telephone system and bell sound detecting method thereof 失效
    电话系统及铃声检测方法

    公开(公告)号:US5758289A

    公开(公告)日:1998-05-26

    申请号:US488077

    申请日:1995-06-07

    摘要: A relay lifter comprises a hook switch unit for turning ON/OFF a hook switch in response to a talk switch, a voice switching unit for switching connection of an aural signal in said corded telephone set between a transmitter/receiver of said corded telephone set and a cordless telephone set, and a bell sound detection signal transfer unit, a bell sound is outputted from said cordless telephone set when a bell sound is detected and an incoming call is accepted, a hook switch is turned ON/OFF using a hook switch ON/OFF unit, and connection of an aural signal in said corded telephone set is switched to said cordless telephone set for transmitting and receiving voice using said cordless telephone set.

    摘要翻译: 一个继电器升降器包括一个用于响应于一个通话开关来打开/关闭一个挂钩开关的挂钩开关单元,一个话音切换单元,用于在所述有线电话机的发送器/接收器之间切换所述有线电话机中的听觉信号的连接, 无绳电话机和铃声检测信号传送单元,当检测到铃声并接受来电时,从所述无绳电话机输出铃声,使用挂钩开关打开/关闭挂钩开关 / OFF单元,并且将所述有线电话机中的听觉信号的连接切换到用于使用所述无绳电话机发送和接收语音的所述无绳电话机。

    Vibrator attaching structure
    10.
    发明授权
    Vibrator attaching structure 失效
    振动器连接结构

    公开(公告)号:US5801466A

    公开(公告)日:1998-09-01

    申请号:US472236

    申请日:1995-06-07

    摘要: A motor 3 having a rotational shaft with a counterweight 4 is held in a vibrator holder 2. The rotational shaft of the motor is inserted at a free end in a circular hole in a bearing-plate of the vibrator holder 2. The vibrator holder 2 with the motor therein is accommodates in a vibrator accommodating section 120 formed in a housing 12 of a portable terminal and fixed with screws 5 to the housing 12. The vibrator holder 120 is then covered with an index cover 17 to thereby complete the vibrator attachment, which reduces a vibrator attaching work load. The inner wall of the vibrator accommodating section 120 faces the motor to thereby prevent the motor 3 from slipping from the holder.

    摘要翻译: 将具有配重4的旋转轴的马达3保持在振动器保持器2中。马达的旋转轴在振动器保持器2的支承板中的圆形孔中的自由端插入。振动器保持器2 其中的电动机容纳在形成在便携式终端的壳体12中的振动器容纳部分120中,并用螺钉5固定到壳体12.然后,振动器保持器120被索引盖17覆盖,从而完成振动器附接, 这减少了振动器附着工作负荷。 振动器容纳部分120的内壁面对电动机,从而防止电动机3从保持器滑落。