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    KIT FOR DETERMINING POLYSACCHARIDE-BINDING ABILITY OF MONONUCLEAR CELLS PRESENT IN PERIPHERAL BLOOD
    3.
    发明申请
    KIT FOR DETERMINING POLYSACCHARIDE-BINDING ABILITY OF MONONUCLEAR CELLS PRESENT IN PERIPHERAL BLOOD 有权
    用于测定外周血中单核细胞多糖结合能力的试剂盒

    公开(公告)号：US20080220452A1

    公开(公告)日：2008-09-11

    申请号：US12117999

    申请日：2008-05-09

    申请人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

    发明人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

    IPC分类号： G01N33/53

    CPC分类号： G01N33/56972 ,  G01N2400/10 ,  Y10S435/975

    摘要： A kit for the determination of the ability of a peripheral blood mononuclear cell to bind to a polysaccharide herein provided comprises a detection reagent comprising a fluorescence-labeled immunostimulant polysaccharide; and a reference reagent comprising a fluorescence-labeled material of a polysaccharide different from that used in the fluorescence-labeled immunostimulant polysaccharide, and/or an immunostimulant polysaccharide which is not labeled with any fluorescent material and whose polysaccharide moiety is identical to that included in the fluorescence-labeled immunostimulant polysaccharide. The use of this kit would permit the estimation of the polysaccharide-binding ability of a peripheral blood mononuclear cell in a higher precision of estimation.

    摘要翻译： 用于测定外周血单核细胞与本文提供的多糖结合的能力的试剂盒包括含有荧光标记的免疫刺激多糖的检测试剂; 和包含不同于荧光标记的免疫刺激多糖中使用的多糖的荧光标记物质的参考试剂，和/或未用任何荧光材料标记的多糖部分与其中包含的多糖部分相同的免疫刺激多糖 荧光标记免疫刺激多糖。 该试剂盒的使用将允许以更高的估计精度估计外周血单核细胞的多糖结合能力。

    Polarization independent optical isolator with integrally assembled birefringent crystal element and Faraday rotator
    4.
    发明授权
    Polarization independent optical isolator with integrally assembled birefringent crystal element and Faraday rotator 失效
    具有整体组装的双折射晶体元件和法拉第旋转器的偏振独立光隔离器

    公开(公告)号：US06048103A

    公开(公告)日：2000-04-11

    申请号：US325318

    申请日：1999-06-03

    申请人： Yukiko Furukata ,  Yasushi Sato ,  Tetsuya Suga

    发明人： Yukiko Furukata ,  Yasushi Sato ,  Tetsuya Suga

    IPC分类号： G02B6/26 ,  G02B6/38

    CPC分类号： G02B6/3825 ,  G02B6/3846 ,  G02B6/2746 ,  G02B6/3821 ,  G02B6/3845 ,  G02B6/3869 ,  G02B6/3874

    摘要： Adapter-type optical isolator 1 has split sleeve 7 within housings A and B. Polarization-independent optical isolator is of such a structure that optical isolator device 3 which is an integral assembly of a Faraday rotator and a birefringent crystal element is provided within hollow cylindrical magnet 4. Beam changing elements 5a and 5b are in the form of optical coupling lenses or core-flared fibers. Adapter-type optical isolator 1 has the polarization-independent optical isolator and beam changing elements 5a and 5b fitted snugly within the bore of split sleeve 7 in the central area in such a way that the polarization-independent optical isolator is held between beam changing elements 5a and 5b. An optical connector using the adapter-type optical isolator 1 is simple in construction, permits simple assembly and adjustments, is small, allows for easy optical adjustments on individual optical parts, features high operational stability and can be incorporated into a wide variety of measuring instruments and communication equipment.

    摘要翻译： 适配器式光隔离器1在壳体A和B内具有分裂套筒7.偏振无关的光隔离器具有如下结构：作为法拉第转子和双折射晶体元件的整体组件的光隔离器3设置在中空圆柱形 光束变换元件5a和5b是光学耦合透镜或纤芯扩张光纤的形式。 适配器型光隔离器1具有偏振无关的光隔离器和光束变换元件5a和5b，这些光隔离器和光束改变元件5a和5b紧密地贴合在中心区域中的分裂套筒7的孔内，使得偏振无关的光隔离器保持在光束变换元件 5a和5b。 使用适配器式光隔离器1的光连接器结构简单，组装和调整简单，体积小，可轻松对各个光学部件进行光学调整，具有操作稳定性高，可并入各种测量仪器 和通讯设备。

    Kit for determining polysaccharide-binding ability of mononuclear cells present in peripheral blood
    7.
    发明申请
    Kit for determining polysaccharide-binding ability of mononuclear cells present in peripheral blood 有权
    用于测定外周血中存在的单核细胞的多糖结合能力的试剂盒

    公开(公告)号：US20070031898A1

    公开(公告)日：2007-02-08

    申请号：US11580936

    申请日：2006-10-16

    申请人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

    发明人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

    IPC分类号： G01N33/567 ,  A61K31/716

    CPC分类号： G01N33/56972 ,  G01N2400/10 ,  Y10S435/975

    摘要： A kit for the determination of the ability of a peripheral blood mononuclear cell to bind to a polysaccharide herein provided comprises a detection reagent comprising a fluorescence-labeled immunostimulant polysaccharide; and a reference reagent comprising a fluorescence-labeled material of a polysaccharide different from that used in the fluorescence-labeled immunostimulant polysaccharide, and/or an immunostimulant polysaccharide which is not labeled with any fluorescent material and whose polysaccharide moiety is identical to that included in the fluorescence-labeled immunostimulant polysaccharide. The use of this kit would permit the estimation of the polysaccharide-binding ability of a peripheral blood mononuclear cell in a higher precision of estimation.

    摘要翻译： 用于测定外周血单核细胞与本文提供的多糖结合的能力的试剂盒包括含有荧光标记的免疫刺激多糖的检测试剂; 和包含不同于荧光标记的免疫刺激多糖中使用的多糖的荧光标记物质的参考试剂，和/或未用任何荧光材料标记的多糖部分与其中包含的多糖部分相同的免疫刺激多糖 荧光标记免疫刺激多糖。 该试剂盒的使用将允许以更高的估计精度估计外周血单核细胞的多糖结合能力。

    Kit for determining polysaccharide-binding activity of mononuclear cells present in peripheral blood
    8.
    发明授权
    Kit for determining polysaccharide-binding activity of mononuclear cells present in peripheral blood 有权
    用于测定外周血中存在的单核细胞的多糖结合活性的试剂盒

    公开(公告)号：US07553824B2

    公开(公告)日：2009-06-30

    申请号：US12117999

    申请日：2008-05-09

    申请人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

    发明人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

    IPC分类号： A01N43/04

    CPC分类号： G01N33/56972 ,  G01N2400/10 ,  Y10S435/975

    摘要： A kit for the determination of the ability of a peripheral blood mononuclear cell to bind to a polysaccharide herein provided comprises a detection reagent comprising a fluorescence-labeled immunostimulant polysaccharide; and a reference reagent comprising a fluorescence-labeled material of a polysaccharide different from that used in the fluorescence-labeled immunostimulant polysaccharide, and/or an immunostimulant polysaccharide which is not labeled with any fluorescent material and whose polysaccharide moiety is identical to that included in the fluorescence-labeled immunostimulant polysaccharide. The use of this kit would permit the estimation of the polysaccharide-binding ability of a peripheral blood mononuclear cell in a higher precision of estimation.

    摘要翻译： 用于测定外周血单核细胞与本文提供的多糖结合的能力的试剂盒包括含有荧光标记的免疫刺激多糖的检测试剂; 和包含不同于荧光标记的免疫刺激多糖中使用的多糖的荧光标记物质的参考试剂，和/或未用任何荧光材料标记的多糖部分与其中包含的多糖部分相同的免疫刺激多糖 荧光标记免疫刺激多糖。 该试剂盒的使用将允许以更高的估计精度估计外周血单核细胞的多糖结合能力。

    Method for estimating immunostimulant activity of a polysaccharide
    9.
    发明授权
    Method for estimating immunostimulant activity of a polysaccharide 有权
    估计多糖免疫刺激活性的方法

    公开(公告)号：US07449452B2

    公开(公告)日：2008-11-11

    申请号：US11580936

    申请日：2006-10-16

    申请人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

    发明人： Tetsuya Suga ,  Yasuyo Suga ,  Masahiro Murata

    IPC分类号： A61N31/715

    CPC分类号： G01N33/56972 ,  G01N2400/10 ,  Y10S435/975

    摘要： The ability of a polysaccharide to act as an immunostimulant may be assessed by comparing the degree of binding of a detection reagent, which contains a fluorescence-labeled version of the polysaccharide, with the binding of a reference reagent, which contains a fluorescence-labeled version of a different polysaccharide. The ability of a polysaccharide to act as an immunostimulant may also be assessed by comparing the degree of binding of a detection reagent, which contains a fluorescence-labeled version of the polysaccharide, with the binding of a different type of reference reagent, which contains both the same fluorescence-labeled version of the polysaccharide and an unlabelled version of the same polysaccharide.

    摘要翻译： 多糖用作免疫刺激剂的能力可以通过比较含有多糖的荧光标记形式的检测试剂与参考试剂的结合程度来评估，所述参考试剂含有荧光标记的版本 的不同多糖。 多糖用作免疫刺激剂的能力也可以通过比较含有多糖的荧光标记形式的检测试剂与不同类型参考试剂的结合的程度来评估，所述参考试剂含有两者 多糖的相同的荧光标记版本和相同多糖的未标记的版本。

    Optical coupler having a tapered fused region
    10.
    发明授权
    Optical coupler having a tapered fused region 失效
    具有锥形熔融区域的光耦合器

    公开(公告)号：US5410626A

    公开(公告)日：1995-04-25

    申请号：US81479

    申请日：1993-06-23

    申请人： Michitaka Okuta ,  Tetsuya Suga ,  Akio Tsugawa ,  Kiyohiko Kuramoto

    发明人： Michitaka Okuta ,  Tetsuya Suga ,  Akio Tsugawa ,  Kiyohiko Kuramoto

    IPC分类号： G02B6/28 ,  G02B6/34 ,  G02B6/00 ,  G02B6/26

    CPC分类号： G02B6/29332 ,  G02B6/2835 ,  G02B6/2856

    摘要： An optical coupler having a tapered fused region produced by locally heating the periphery of a plurality of aligned optical fibers, each having a core and a cladding, so that the optical fibers fuse together at the heated part, and then drawing the resulting fused region by pulling. The length of the fused region is not longer than 10 mm. The tapered fused region may be provided in such a manner that a plurality of optical fibers are disposed to intersect each other at a predetermined angle, and the intersecting portions are locally heated so as to fuse together and then subjected to pulling. The tapered fused region may be provided at each of two or more positions. Also disclosed is an optical coupler wherein at least one of a plurality of optical fibers each having a core and a cladding is previously heat-treated at a high temperature to enlarge the core in a portion thereof, and the enlarged-core portion of this optical fiber is fused to the other optical fibers and then subjected to pulling, thereby forming a tapered fused region.

    摘要翻译： 一种具有锥形熔融区域的光耦合器，其通过局部加热多个对准的光纤的周边而产生，每个具有芯和包层，使得光纤在加热部分处熔合在一起，然后通过 拉扯 熔融区域的长度不大于10mm。 锥形熔融区域可以以使得多个光纤以预定角度彼此相交的方式设置，并且交叉部分被局部加热以熔合在一起然后进行拉伸。 可以在两个或更多个位置中的每一个处设置锥形熔合区域。 还公开了一种光耦合器，其中每个具有芯和包层的多个光纤中的至少一个预先在高温下进行热处理以在其一部分中扩大芯部，并且该光学器件的放大芯部分 纤维与其他光纤熔合，然后进行拉伸，从而形成锥形的熔融区域。