专利检索 ap:("Takeda Pharmaceutical Company Limited") AND inv:"William Buffham" 第 1 页

1.

发明授权
Compounds 有权

公开(公告)号：US09464060B2

公开(公告)日：2016-10-11

申请号：US14463780

申请日：2014-08-20

申请人： TAKEDA PHARMACEUTICAL COMPANY LIMITED

发明人： William Buffham , Hannah Canning , Richard Davenport , William Farnaby , Stephen Mack , Alka Parmar , Susanne Wright

IPC分类号： C07D239/34 , C07D213/78 , C07D213/81 , C07C235/52 , C07C235/46

CPC分类号： C07D239/34 , A61K31/195 , A61K31/277 , A61K31/44 , A61K31/505 , C07C235/44 , C07C235/46 , C07C235/52 , C07C255/54 , C07C2601/02 , C07C2601/04 , C07D213/78 , C07D213/81

摘要： The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, X, m, R2, Y, R3, Z, n, R4, A and B are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

2.

发明授权
Amide derivatives as lysophosphatidic acid receptor antagonists 有权

公开(公告)号：US10100018B2

公开(公告)日：2018-10-16

申请号：US14913135

申请日：2014-08-20

申请人： Takeda Pharmaceutical Company Limited

发明人： William Buffham , Hannah Canning , Richard Davenport , William Farnaby , Stephen Mack , Alka Parmar , Susanne Wright

IPC分类号： C07C235/52 , A61P29/00 , C07D239/34 , C07D213/81 , C07C235/46 , C07D213/78 , A61K31/195 , A61K31/277 , A61K31/44 , A61K31/505 , C07C235/44 , C07C255/54

摘要： The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, X, m, R2, Y, R3, Z, n, R4, A and B are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

3.

发明申请
Amide derivatives as lysophosphatidic acid receptor antagonists 审中-公开

公开(公告)号：US20190010129A1

公开(公告)日：2019-01-10

申请号：US15999570

申请日：2018-08-20

申请人： Takeda Pharmaceutical Company Limited

发明人： William Buffham , Hannah Canning , Richard Davenport , William Farnaby , Stephen Mack , Alka Parmar , Susanne Wright

IPC分类号： C07D239/34 , C07C255/54 , A61K31/44 , A61K31/505 , C07C235/44 , C07D213/81 , A61K31/277 , C07D213/78 , C07C235/46 , C07C235/52 , A61K31/195

摘要： The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, formula (I) wherein R1, X, m, R2, Y, R3, Z, n, R4, A and B are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.