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公开(公告)号：US20230338503A1
公开(公告)日：2023-10-26
申请号：US18322679
申请日：2023-05-24
IPC分类号： A61K39/12 , A61K39/125 , A61K39/39
CPC分类号： A61K39/12 , A61K39/125 , A61K39/39 , A61K2039/55505
摘要： The present invention relates to single dose parenteral vaccine compositions comprising mixtures of monovalent Norovirus virus-like particles. Methods of conferring protective immunity against Norovirus infections in a human subject by administering such compositions are also disclosed.
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公开(公告)号：US20160317645A1
公开(公告)日：2016-11-03
申请号：US15144265
申请日：2016-05-02
发明人： Thomas S. VEDVICK , Bryan STEADMAN , Charles RICHARDSON , Thomas R. FOUBERT , Charles R. PETRIE
CPC分类号： A61K39/12 , C07K1/18 , C07K14/005 , C12N7/00 , C12N2770/16023 , C12N2770/16034 , C12N2770/16051
摘要： Methods for purifying human Calciviruses are disclosed, including Noroviruses and Sapoviruses.
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公开(公告)号：US20180185468A1
公开(公告)日：2018-07-05
申请号：US15836030
申请日：2017-12-08
IPC分类号： A61K39/12 , A61K39/39 , A61K39/125 , A61K39/00
摘要： The present invention relates to single dose parental vaccine compositions comprising mixtures of monovalent Norovirus virus-like particles. Methods of conferring protective immunity against Norovirus infections in a human subject by administering such compositions are also disclosed.
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公开(公告)号：US20160008455A1
公开(公告)日：2016-01-14
申请号：US14796714
申请日：2015-07-10
IPC分类号： A61K39/125 , A61K39/39 , C12N7/00
CPC分类号： A61K39/12 , A61K39/125 , A61K39/39 , A61K2039/5258 , A61K2039/54 , A61K2039/543 , A61K2039/55572 , A61K2039/70 , C07K16/10 , C12N7/00 , C12N2770/16023 , C12N2770/16034
摘要： The present invention relates to antigenic and vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to a process for the production of both monovalent and multivalent VLPs, the VLPs comprising capsid proteins from one or more Norovirus genogroups.
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公开(公告)号：US20240316175A1
公开(公告)日：2024-09-26
申请号：US18490157
申请日：2023-10-19
CPC分类号： A61K39/12 , C12N7/00 , A61K2039/5258 , A61K2039/543 , A61K2039/55572 , A61K2039/55583 , C12N2770/16023 , C12N2770/16034
摘要： The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.
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公开(公告)号：US20220143169A1
公开(公告)日：2022-05-12
申请号：US17348045
申请日：2021-06-15
摘要： The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.
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公开(公告)号：US20200345827A1
公开(公告)日：2020-11-05
申请号：US16870020
申请日：2020-05-08
摘要： The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject.
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公开(公告)号：US20160000899A1
公开(公告)日：2016-01-07
申请号：US14796614
申请日：2015-07-10
IPC分类号： A61K39/12
CPC分类号： A61K39/12 , A61K39/125 , A61K39/39 , A61K2039/5258 , A61K2039/545 , A61K2039/55505 , A61K2039/55572 , A61K2039/70 , C12N2770/16034
摘要： The present invention relates to single dose parenteral vaccine compositions comprising mixtures of monovalent Norovirus virus-like particles. Methods of conferring protective immunity against Norovirus infections in a human subject by administering such compositions are also disclosed.
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公开(公告)号：US20190125853A1
公开(公告)日：2019-05-02
申请号：US15994887
申请日：2018-05-31
IPC分类号： A61K39/12 , A61K39/125 , C07K16/10 , C12N7/00 , A61K39/39
CPC分类号： A61K39/12 , A61K39/125 , A61K39/39 , A61K2039/5258 , A61K2039/54 , A61K2039/543 , A61K2039/55572 , A61K2039/70 , C07K16/10 , C12N7/00 , C12N2770/16023 , C12N2770/16034
摘要： The present invention relates to antigenic and vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to a process for the production of both monovalent and multivalent VLPs, the VLPs comprising capsid proteins from one or more Norovirus genogroups.
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