公开(公告)号：US20100227332A1

公开(公告)日：2010-09-09

申请号：US12800003

申请日：2010-05-06

申请人： Taro Iizumi ,  Hiroyuki Suzuki ,  Hirohisa Tashiro

发明人： Taro Iizumi ,  Hiroyuki Suzuki ,  Hirohisa Tashiro

IPC分类号： C12Q1/68

CPC分类号： D21G9/0009 ,  C02F1/50 ,  C12N15/10 ,  C12Q1/18 ,  C12Q1/689 ,  D21F1/00

摘要： The present invention provides for a method for selecting an antimicrobial agent, which comprises a microbe analyzing step in which microbes in the microbial biota of a sample are analyzed based on base sequence of DNA and an antimicrobial agent selecting step comprising performing search in a data base storing data for industrial antimicrobial agents applicable to the analyzed microbes recited at effective concentrations, picking up industrial antimicrobial agents effective for the microbial biota, dominant microbe or specific microbe(s) in the sample analyzed in the above microbe analyzing step and selecting among the picked up ones an industrial antimicrobial agent, which method permits to select an antimicrobial agent that is optimum for the treatment in a simple and assured manner within a brief time and to grasp whether the effect of the antimicrobial agent is revealed or not in a simple and assured manner within a brief time, by utilizing this selecting method for the selection of antimicrobial agent, for example, in an antimicrobial treating, in monitoring of the antimicrobial effect, in slime control in paper manufacturing process courses and in microbe inhibition in paper manufacturing process courses, whereby troubles caused by growth of microbes can be prevented beforehand.

摘要翻译： 本发明提供一种选择抗微生物剂的方法，其包括微生物分析步骤，其中基于DNA的碱基序列分析样品的微生物生物群中的微生物，以及抗微生物剂选择步骤，包括在数据库中进行搜索 存储适用于以有效浓度列出的分析的微生物的工业抗微生物剂的数据，拾取对微生物生物群有效的工业抗微生物剂，在上述微生物分析步骤中分析的样品中的主要微生物或特定微生物，并在挑选的 该方法允许在短时间内以简单且有保证的方式选择最适于治疗的抗微生物剂，并且了解抗微生物剂的效果是否显示在简单且有保证的范围内 通过利用该选择方法进行选择 的抗微生物剂，例如在抗微生物处理中，用于监测抗微生物效果，在纸制造过程中的粘液控制和造纸工艺过程中的微生物抑制，从而可以预先防止由微生物生长引起的麻烦。

公开(公告)号：US20070117140A1

公开(公告)日：2007-05-24

申请号：US11640755

申请日：2006-12-18

申请人： Taro Iizumi ,  Hiroyuki Suzuki ,  Hirohisa Tashiro

发明人： Taro Iizumi ,  Hiroyuki Suzuki ,  Hirohisa Tashiro

IPC分类号： C12Q1/68 ,  G06F19/00

CPC分类号： D21G9/0009 ,  C02F1/50 ,  C12N15/10 ,  C12Q1/18 ,  C12Q1/689 ,  D21F1/00

摘要： The present invention provides for a method for selecting an antimicrobial agent, which comprises a microbe analyzing step in which microbes in the microbial biota of a sample are analyzed based on base sequence of DNA and an antimicrobial agent selecting step comprising performing search in a data base storing data for industrial antimicrobial agents applicable to the analyzed microbes recited at effective concentrations, picking up industrial antimicrobial agents effective for the microbial biota, dominant microbe or specific microbe(s) in the sample analyzed in the above microbe analyzing step and selecting among the picked up ones an industrial antimicrobial agent, which method permits to select an antimicrobial agent that is optimum for the treatment in a simple and assured manner within a brief time and to grasp whether the effect of the antimicrobial agent is revealed or not in a simple and assured manner within a brief time, by utilizing this selecting method for the selection of antimicrobial agent, for example, in an antimicrobial treating, in monitoring of the antimicrobial effect, in slime control in paper manufacturing process courses and in microbe inhibition in paper manufacturing process courses, whereby troubles caused by growth of microbes can be prevented beforehand.

摘要翻译： 本发明提供一种选择抗微生物剂的方法，其包括微生物分析步骤，其中基于DNA的碱基序列分析样品的微生物生物群中的微生物，以及抗微生物剂选择步骤，包括在数据库中进行搜索 存储适用于以有效浓度列出的分析的微生物的工业抗微生物剂的数据，拾取对微生物生物群有效的工业抗微生物剂，在上述微生物分析步骤中分析的样品中的主要微生物或特定微生物，并在挑选的 该方法允许在短时间内以简单且有保证的方式选择最适于治疗的抗微生物剂，并且了解抗微生物剂的效果是否显示在简单且有保证的范围内 通过利用该选择方法进行选择 的抗微生物剂，例如在抗微生物处理中，用于监测抗微生物效果，在纸制造过程中的粘液控制和造纸工艺过程中的微生物抑制，从而可以预先防止由微生物生长引起的麻烦。

公开(公告)号：US5306636A

公开(公告)日：1994-04-26

申请号：US639330

申请日：1991-01-10

申请人： Taro Iizumi ,  Koichi Nakamura ,  Tetsuro Fukase

发明人： Taro Iizumi ,  Koichi Nakamura ,  Tetsuro Fukase

IPC分类号： C12N1/21 ,  C12N9/20 ,  C12N15/09 ,  C12N15/55 ,  C12R1/19 ,  C12R1/38 ,  C12N15/74

CPC分类号： C12N9/20

摘要： A thermostable lipase gene coding for a thermostable lipase, a vector having this gene, a transformant containing this vector, methods for preparing them and for preparing a thermostable lipase by cultivating the transformant are disclosed. The thermostable lipase gene is obtained from a cell belonging to the bacterial strain Pseudomonas sp. KWI-56 by a technique of genetic engineering. The thermostable lipase gene is inserted into a high expression vector, which is introduced into a cell of a host microorganism to prepare a transformant. By cultivating this transformant, a thermostable lipase can be produced.

摘要翻译： 公开了编码热稳定性脂肪酶的热稳定性脂肪酶基因，具有该基因的载体，含该载体的转化体，通过培养转化体制备热稳定性脂肪酶的方法和制备热稳定性脂肪酶。 热稳定脂肪酶基因是从属于细菌菌株假单胞菌属（Pseudomonas sp。）的细胞获得的。 KWI-56基因工程技术。 将热稳定性脂肪酶基因插入高表达载体中，将其导入宿主微生物的细胞中以制备转化体。 通过培养该转化体，可以生产耐热脂肪酶。