公开(公告)号：US20150259390A1

公开(公告)日：2015-09-17

申请号：US14725962

申请日：2015-05-29

Applicant: Tel Hashomer Medical Research, Infrastructure and Services Ltd.

Inventor： Amir ZLOTKIN

IPC: C07K14/435 ,  C02F1/44 ,  C02F1/50 ,  C07K7/06 ,  C07K7/08

CPC classification number: C07K14/435 ,  C02F1/441 ,  C02F1/50 ,  C02F2303/04 ,  C02F2303/20 ,  C07K7/06 ,  C07K7/08 ,  C07K14/43595

Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence selected from the group consisting of FDYDWY (SEQ ID NO: 2), SFSQNKSVHSFDYDWYNVSDQADLKN (SEQ ID NO: 3) or CSFSQNKSVHSFDYDWYNVSDQADLKNC (SEQ ID NO: 1), or any cyclized version thereof, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.

Abstract translation: 包含分离的肽的组合物，其可以例如任选地包含选自FDYDWY（SEQ ID NO：2），SFSQNKSVHSFDYDWYNVSDQADLKN（SEQ ID NO：3）或CSFSQNKSVHSFDYDWYNVSDQADLKNC（SEQ ID NO：1）的序列，或任何环化的 版本及其使用方法，包括用于治疗或预防微生物生物膜的形成和细胞粘附于表面。

公开(公告)号：US20180016311A1

公开(公告)日：2018-01-18

申请号：US15721404

申请日：2017-09-29

Applicant: Tel Hashomer Medical Research, Infrastructure and Services Ltd.

Inventor： Amir ZLOTKIN ,  Hen Kestenboim

IPC: C07K14/435 ,  A61L27/22 ,  C07K14/415 ,  C07K7/08 ,  C07K7/06 ,  C07K14/46 ,  A61L27/34 ,  C02F1/50 ,  A61L31/16 ,  A61L31/10 ,  A61L31/04 ,  A61L29/16 ,  A61L29/08 ,  A61L29/04 ,  C09D5/16 ,  C02F3/34

CPC classification number: C07K14/43595 ,  A61L27/227 ,  A61L27/34 ,  A61L29/048 ,  A61L29/085 ,  A61L29/16 ,  A61L31/047 ,  A61L31/10 ,  A61L31/16 ,  C02F1/50 ,  C02F3/34 ,  C02F2303/20 ,  C07K7/06 ,  C07K7/08 ,  C07K14/415 ,  C07K14/461 ,  C09D5/1625

Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence selected from the group consisting of YDYNWY (SEQ ID NO: 1), YDYNLY (SEQ ID NO: 2), FDYNFY (SEQ ID NO: 3), FDYNLY (SEQ ID NO: 4), FDYNWY (SEQ ID NO: 5), YDWNLY (SEQ ID NO: 6), YDWHLY (SEQ ID NO: 7), and WDYNLY (SEQ ID NO: 8), extracted from organisms such as aquatic organisms and moss or any other sequence described herein, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.

公开(公告)号：US20140155318A1

公开(公告)日：2014-06-05

申请号：US14016480

申请日：2013-09-03

Applicant: Tel Hashomer Medical Research, Infrastructure and Services Ltd.

Inventor： Amir ZLOTKIN

IPC: C07K14/435 ,  C07K7/08 ,  C07K7/06

CPC classification number: C07K14/435 ,  C02F1/441 ,  C02F1/50 ,  C02F2303/04 ,  C02F2303/20 ,  C07K7/06 ,  C07K7/08 ,  C07K14/43595

Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence selected from the group consisting of FDYDWY (SEQ ID NO: 2), SFSQNKSVHSFDYDWYNVSDQADLKN (SEQ ID NO: 3) or CSFSQNKSVHSFDYDWYNVSDQADLKNC (SEQ ID NO: 1), or any cyclized version thereof, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.

Abstract translation: 包含分离的肽的组合物，其可以例如任选地包含选自FDYDWY（SEQ ID NO：2），SFSQNKSVHSFDYDWYNVSDQADLKN（SEQ ID NO：3）或CSFSQNKSVHSFDYDWYNVSDQADLKNC（SEQ ID NO：1）的序列，或任何环化的 版本及其使用方法，包括用于治疗或预防微生物生物膜的形成和细胞粘附于表面。

公开(公告)号：US20200095293A1

公开(公告)日：2020-03-26

申请号：US16704849

申请日：2019-12-05

Applicant: TEL HASHOMER MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD.

Inventor： Amir ZLOTKIN

IPC: C07K14/435 ,  C07K7/06 ,  C07K7/08 ,  C02F1/50 ,  C02F1/44

Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence consisting of SVHSFDYDWYNV, or any cyclized version thereof, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.

公开(公告)号：US20200062808A1

公开(公告)日：2020-02-27

申请号：US16680366

申请日：2019-11-11

Applicant: TEL HASHOMER MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD.

Inventor： Amir ZLOTKIN

IPC: C07K14/435 ,  C02F1/50 ,  C02F1/44 ,  C07K7/08 ,  C07K7/06

Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence selected from the group consisting of FDYDWY (SEQ ID NO: 2), SFSQNKSVHSFDYDWYNVSDQADLKN (SEQ ID NO: 3) or CSFSQNKSVHSFDYDWYNVSDQADLKNC (SEQ ID NO: 1), or any cyclized version thereof, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.

公开(公告)号：US20150315253A1

公开(公告)日：2015-11-05

申请号：US14708014

申请日：2015-05-08

Applicant: Tel Hashomer Medical Research, Infrastructure and Services Ltd.

Inventor： Amir ZLOTKIN ,  Hen Kestenboim

IPC: C07K14/435

CPC classification number: C07K14/43595 ,  A61L27/227 ,  A61L27/34 ,  A61L29/048 ,  A61L29/085 ,  A61L29/16 ,  A61L31/047 ,  A61L31/10 ,  A61L31/16 ,  C02F1/50 ,  C02F3/34 ,  C02F2303/20 ,  C07K7/06 ,  C07K7/08 ,  C07K14/415 ,  C07K14/461 ,  C09D5/1625

Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence selected from the group consisting of YDYNWY, YDYNLY, FDYNFY, FDYNLY, FDYNWY, YDWNLY, YDWHLY and WDYNLY, extracted from organisms such as aquatic organisms and mossor any other sequence described herein, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.

Abstract translation: 包含分离的肽的组合物，其可以例如任选地包含选自YDYNWY，YDYNLY，FDYNFY，FDYNLY，FDYNWY，YDWNLY，YDWHLY和WDYNLY的序列，其从诸如水生生物和苔藓的生物体提取，本文所述的任何其它序列 以及使用它们的方法，包括用于治疗或预防微生物生物膜的形成和细胞粘附到表面。