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1.
公开(公告)号:US20150086447A1
公开(公告)日:2015-03-26
申请号:US14524685
申请日:2014-10-27
申请人: Gregory Mathus , Terrence Kelly , Richard Cote
发明人: Gregory Mathus , Terrence Kelly , Richard Cote
IPC分类号: B01L3/02
CPC分类号: B01L3/0217 , B01L3/0275 , B01L3/0279 , B01L2200/023 , B01L2200/025 , B01L2200/0689 , B01L2200/087 , B01L2300/027 , Y10T137/0318 , Y10T436/2575
摘要: The pipetting method is directed to mounting and ejecting a disposable pipette tip. The pipetting system has one or more tip mounting shafts with an upper locking section and a lower sealing section. The upper locking section has outwardly extending lobes spaced around the mounting shaft and located above a stop member. The lower sealing section on the tip mounting shaft is located below the stop. As the mounting shaft is inserted into the collar of the disposable pipette, the collar distorts out of round and engages the lobes on the upper locking section of the tip mounting shaft. Contemporaneously, the lower sealing section of the mounting shaft seals against the barrel of the disposable pipette tip.
摘要翻译: 移液方法涉及安装和喷射一次性吸头。 移液系统具有一个或多个具有上部锁定部分和下部密封部分的尖端安装轴。 上锁定部分具有围绕安装轴间隔开并位于止动件上方的向外延伸的凸角。 刀片安装轴上的下密封部分位于挡块下方。 当安装轴插入到一次性移液管的轴环中时,套环从圆形变形并与尖端安装轴的上部锁定部分上的凸角接合。 同时,安装轴的下密封部分密封在一次性移液管尖端的筒体上。
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公开(公告)号:US20100034706A1
公开(公告)日:2010-02-11
申请号:US12578714
申请日:2009-10-14
申请人: Gregory Mathus , Terrence Kelly , Richard Cote
发明人: Gregory Mathus , Terrence Kelly , Richard Cote
IPC分类号: B01L3/02
CPC分类号: B01L3/0217 , B01L3/0275 , B01L3/0279 , B01L2200/023 , B01L2200/025 , B01L2200/0689 , B01L2200/087 , B01L2300/027 , Y10T137/0318 , Y10T436/2575
摘要: In one aspect, the invention relates to a pipette tip mounting shaft configuration and a disposable pipette tip having a matching configuration. The mounting shaft includes a locking section located above a lower sealing section. The locking section has outwardly extending locking lobes located above a stop member and a lower sealing section located below the stop member. In certain embodiments, the diameter of the mounting shaft below the stop member is reduced in order to lessen insertion and ejection forces, which is particularly helpful for hand-held multi-channel pipettors. In these embodiments, the lower sealing section contains either a frustoconical sealing section, or an annular groove and a sealing ring, such as a flouroelastomeric O-ring seal. When the mounting shaft is fully inserted into the collar of the mating disposable pipette tip, the tip locks onto the mounting shaft. The bore of the pipette tip includes a circumferential shelf or shoulder separating its upper collar from the tip sealing area which is located below the circumferential shelf. The tip collar preferably includes a locking ring located at or near the upper opening for the mounting shaft. The dimensions of the collar, and in particular the distance between its circumferential shelf and the locking ring, are selected to match the dimensions of the mounting shaft between the stop member and the upper end of the locking lobes, thus locking the pipette tip in a secure, reliable position and orientation while using ergonomic insertion and ejection forces. The locking lobes preferably include a ramp portion that gently flexes and distorts the pipette tip collar out of round as the mounting shaft is inserted in the pipette tip, rather than stretching the tip collar. The circumferential shelf on the pipette tip between the tip collar and the barrel isolates the sealing area at the upper end of the barrel from distortion, thus facilitating reliable sealing engagement between the lower sealing section of the mounting shaft and the sealing ring in the upper end of the barrel of the pipette tip.
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公开(公告)号:US20080286157A1
公开(公告)日:2008-11-20
申请号:US11934381
申请日:2007-11-02
申请人: Gregory Mathus , Terrence Kelly , Richard Cote
发明人: Gregory Mathus , Terrence Kelly , Richard Cote
IPC分类号: B01L3/02
CPC分类号: B01L3/0217 , B01L3/0275 , B01L3/0279 , B01L2200/023 , B01L2200/025 , B01L2200/0689 , B01L2200/087 , B01L2300/027 , Y10T137/0318 , Y10T436/2575
摘要: In one aspect, the invention relates to a pipette tip mounting shaft configuration and a disposable pipette tip having a matching configuration. The mounting shaft includes a locking section located above a lower sealing section. The locking section has outwardly extending locking lobes located above a stop member and a lower sealing section located below the stop member. In certain embodiments, the diameter of the mounting shaft below the stop member is reduced in order to lessen insertion and ejection forces, which is particularly helpful for hand-held multi-channel pipettors. In these embodiments, the lower sealing section contains either a frustoconical sealing section, or an annular groove and a sealing ring, such as a flouroelastomeric O-ring seal. When the mounting shaft is fully inserted into the collar of the mating disposable pipette tip, the tip locks onto the mounting shaft. The bore of the pipette tip includes a circumferential shelf or shoulder separating its upper collar from the tip sealing area which is located below the circumferential shelf. The tip collar preferably includes a locking ring located at or near the upper opening for the mounting shaft. The dimensions of the collar, and in particular the distance between its circumferential shelf and the locking ring, are selected to match the dimensions of the mounting shaft between the stop member and the upper end of the locking lobes, thus locking the pipette tip in a secure, reliable position and orientation while using ergonomic insertion and ejection forces. The locking lobes preferably include a ramp portion that gently flexes and distorts the pipette tip collar out of round as the mounting shaft is inserted in the pipette tip, rather than stretching the tip collar. The circumferential shelf on the pipette tip between the tip collar and the barrel isolates the sealing area at the upper end of the barrel from distortion, thus facilitating reliable sealing engagement between the lower sealing section of the mounting shaft and the sealing ring in the upper end of the barrel of the pipette tip.
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公开(公告)号:US07662343B2
公开(公告)日:2010-02-16
申请号:US11552384
申请日:2006-10-24
申请人: Gregory Mathus , Terrence Kelly , Richard Cote
发明人: Gregory Mathus , Terrence Kelly , Richard Cote
IPC分类号: B01L3/02
CPC分类号: B01L3/0279 , B01L2200/023 , B01L2200/025 , B01L2200/087
摘要: The invention relates to a pipette tip mounting shaft configuration and a disposable pipette tip having a matching configuration. The mounting shaft includes a locking section located above a lower sealing section. The locking section has outwardly extending locking lobes circumferentially spaced around the mounting shaft and located above a stop member that separates the lower sealing section from the upper locking section. When the mounting shaft is fully inserted into the collar of the mating disposable pipette tip, the tip locks onto the mounting shaft. The bore of the pipette tip includes a circumferential shelf separating its upper collar from the tip sealing area which is located below the circumferential shelf. The locking lobes gently flexes and distorts the pipette tip collar out of round as the mounting shaft is inserted in the pipette tip, rather than stretching the tip collar. The circumferential shelf on the pipette tip between the tip collar and the barrel isolates the sealing area at the upper end of the barrel from distortion, thus facilitating reliable sealing engagement.
摘要翻译: 本发明涉及移液器吸头安装轴构造和具有匹配构型的一次性吸头。 安装轴包括位于下密封部分上方的锁定部分。 锁定部分具有沿安装轴周向间隔开的向外延伸的锁定凸角,并且位于将下部密封部分与上部锁定部分分离的止挡部件上方。 当安装轴完全插入到匹配的一次性移液管尖端的轴环中时,尖端锁定在安装轴上。 移液管尖端的孔包括将其上部套环与位于周向架下方的尖端密封区域分开的周向架。 当安装轴插入移液管尖端时,锁定凸耳轻轻地弯曲和扭曲移液管尖端套环,而不是拉伸尖端套环。 吸头尖端在圆顶架和圆筒之间的圆周架子隔开了筒体上端的密封区域,使其不会变形,从而有利于可靠的密封接合。
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公开(公告)号:US08277757B2
公开(公告)日:2012-10-02
申请号:US12568801
申请日:2009-09-29
申请人: Terrence Kelly , Richard Cote , Gregory Mathus
发明人: Terrence Kelly , Richard Cote , Gregory Mathus
CPC分类号: B01L3/0279 , B01L3/021 , B01L2200/0689 , B01L2200/141 , B01L2400/0487
摘要: A pipette tip mounting shaft includes outwardly circumferentially extending locking lobes over which the pipette tip collar is mounted. The locking lobes preferably include an inclining ramp portion that gently flexes and distorts the pipette tip collar out-of-round as the mounting shaft is inserted into the pipette tip, rather than the stretching tip collar. Each locking lobe also includes a declining ramp portion which extends upward along the mounting shaft. The peak of the lobes is preferably curved. When the pipette tip is fully mounted on the mounting shaft, a locking ring on the inside surface of the tip collar engages the declining ramp of the lobes to provide an over-center engagement, however, the required ejection force is small.
摘要翻译: 移液管尖端安装轴包括向外周向延伸的锁定凸耳,移液管尖端套环安装在该凸起上。 锁定凸耳优选地包括倾斜斜面部分,当倾斜安装轴插入移液管尖端而不是拉伸尖端套环时,倾斜斜坡部分轻轻地弯曲和扭曲移液管尖端轴环。 每个锁定凸耳还包括沿安装轴向上延伸的下降斜面部分。 裂片的峰最好是弯曲的。 当移液管末端完全安装在安装轴上时,尖端套环的内表面上的锁定环接合凸角的下降斜面以提供过中心接合,然而,所需的弹出力很小。
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公开(公告)号:US08501118B2
公开(公告)日:2013-08-06
申请号:US12578714
申请日:2009-10-14
申请人: Gregory Mathus , Terrence Kelly , Richard Cote
发明人: Gregory Mathus , Terrence Kelly , Richard Cote
IPC分类号: B01L3/02
CPC分类号: B01L3/0217 , B01L3/0275 , B01L3/0279 , B01L2200/023 , B01L2200/025 , B01L2200/0689 , B01L2200/087 , B01L2300/027 , Y10T137/0318 , Y10T436/2575
摘要: A disposable pipette tip having that is configured to mount on a tip mounting shaft having a locking section and a separate sealing section. The locking section has outwardly extending locking lobes circumferentially spaced around the mounting shaft and located above a stop member that separates the lower sealing section from the upper locking section. The collar flexes out of round when it is mounted over the locking lobes on the mounting shaft. The circumferential shelf on the tip isolates the tip barrel from distortion to enable robust sealing in the barrel below the shelf.
摘要翻译: 具有该移液管尖头的一次性移液管尖端配置成安装在具有锁定部分和单独的密封部分的尖端安装轴上。 锁定部分具有沿安装轴周向间隔开的向外延伸的锁定凸角,并且位于将下部密封部分与上部锁定部分分离的止挡部件上方。 当套环安装在安装轴上的锁定凸角上时,套环会弹出。 尖端的圆周架子将尖端筒体分离,以防止变形,从而能够在机架下方的筒体上牢固地密封。
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公开(公告)号:US20110076205A1
公开(公告)日:2011-03-31
申请号:US12568801
申请日:2009-09-29
申请人: Terrence Kelly , Richard Cote , Gregory Mathus
发明人: Terrence Kelly , Richard Cote , Gregory Mathus
IPC分类号: B01L3/02
CPC分类号: B01L3/0279 , B01L3/021 , B01L2200/0689 , B01L2200/141 , B01L2400/0487
摘要: A pipette tip mounting shaft includes outwardly circumferentially extending locking lobes over which the pipette tip collar is mounted. The locking lobes preferably include an inclining ramp portion that gently flexes and distorts the pipette tip collar out-of-round as the mounting shaft is inserted into the pipette tip, rather than the stretching tip collar. Each locking lobe also includes a declining ramp portion which extends upward along the mounting shaft. The peak of the lobes is preferably curved. When the pipette tip is fully mounted on the mounting shaft, a locking ring on the inside surface of the tip collar engages the declining ramp of the lobes to provide an over-center engagement, however, the required ejection force is small.
摘要翻译: 移液管尖端安装轴包括向外周向延伸的锁定凸耳,移液管尖端套环安装在该凸起上。 锁定凸耳优选地包括倾斜斜面部分,当倾斜安装轴插入移液管尖端而不是拉伸尖端套环时,倾斜斜坡部分轻轻地弯曲和扭曲移液管尖端轴环。 每个锁定凸耳还包括沿安装轴向上延伸的下降斜面部分。 裂片的峰最好是弯曲的。 当移液管末端完全安装在安装轴上时,尖端套环的内表面上的锁定环接合凸角的下降斜面以提供过中心接合,然而,所需的弹出力很小。
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公开(公告)号:US07662344B2
公开(公告)日:2010-02-16
申请号:US11934381
申请日:2007-11-02
申请人: Gregory Mathus , Terrence Kelly , Richard Cote
发明人: Gregory Mathus , Terrence Kelly , Richard Cote
IPC分类号: B01L3/02
CPC分类号: B01L3/0217 , B01L3/0275 , B01L3/0279 , B01L2200/023 , B01L2200/025 , B01L2200/0689 , B01L2200/087 , B01L2300/027 , Y10T137/0318 , Y10T436/2575
摘要: The invention relates to a pipette tip mounting shaft configuration and a disposable pipette tip having a matching configuration. The mounting shaft includes a locking section located above a lower sealing section. The locking section has outwardly extending locking lobes circumferentially spaced around the mounting shaft and located above a stop member that separates the lower sealing section from the upper locking section. In certain embodiments, the diameter of the mounting shaft below the stop member is reduced in order to lessen insertion and ejection forces, which is particularly helpful for hand-held multi-channel pipettors. In these embodiments, the lower sealing section contains either a frustoconical sealing section, or an annular groove and a sealing ring, such as a flouroelastomeric O-ring seal.
摘要翻译: 本发明涉及移液器吸头安装轴构造和具有匹配构型的一次性吸头。 安装轴包括位于下密封部分上方的锁定部分。 锁定部分具有沿安装轴周向间隔开的向外延伸的锁定凸角,并且位于将下部密封部分与上部锁定部分分离的止挡部件上方。 在某些实施例中,降低止动件下方的安装轴的直径以减小插入和弹出力,这对手持式多通道移液器特别有帮助。 在这些实施例中,下密封部分包含截头圆锥形密封部分或环形凹槽和密封环,例如光滑弹性O形环密封件。
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公开(公告)号:US20090074622A1
公开(公告)日:2009-03-19
申请号:US11856232
申请日:2007-09-17
申请人: George Kalamakis , Gary Nelson , Gregory Mathus , Terrence Kelly , Joel Novak , Kenneth Steiner , Jonathan Finger
发明人: George Kalamakis , Gary Nelson , Gregory Mathus , Terrence Kelly , Joel Novak , Kenneth Steiner , Jonathan Finger
IPC分类号: B01L3/02
CPC分类号: B01L3/0217 , B01L3/0237 , B01L2200/0605 , B01L2200/087 , B01L2300/027 , B01L2400/0478 , G06F1/1626 , G06F1/1656 , G06F1/169
摘要: A hand-held electronic pipettor includes menu driven software for controlling the information displayed on the user interface display, for inputting information to program the pipettor and for controlling the operation of the pipettor.
摘要翻译: 手持式电子移液器包括用于控制显示在用户界面显示上的信息的菜单驱动软件,用于输入信息以编程移液器并控制移液器的操作。
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公开(公告)号:US08033188B2
公开(公告)日:2011-10-11
申请号:US11856232
申请日:2007-09-17
申请人: George Kalmakis , Gary Nelson , Gregory Mathus , Terrence Kelly , Joel Novak , Kenneth Steiner , Jonathan Finger
发明人: George Kalmakis , Gary Nelson , Gregory Mathus , Terrence Kelly , Joel Novak , Kenneth Steiner , Jonathan Finger
CPC分类号: B01L3/0217 , B01L3/0237 , B01L2200/0605 , B01L2200/087 , B01L2300/027 , B01L2400/0478 , G06F1/1626 , G06F1/1656 , G06F1/169
摘要: A hand-held electronic pipettor includes menu driven software for controlling the information displayed on the user interface display, for inputting information to program the pipettor and for controlling the operation of the pipettor.
摘要翻译: 手持式电子移液器包括用于控制显示在用户界面显示上的信息的菜单驱动软件,用于输入信息以编程移液器并控制移液器的操作。
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