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公开(公告)号：US20240139747A1
公开(公告)日：2024-05-02
申请号：US18545923
申请日：2023-12-19
发明人： Lawrence Chiu , Ion Iordanoaia , Reiner Hitt , Vijay Namasivayam , Eduard Nawrocki , Michael Neugebauer , Tim Moulton , Sam Palmer , Gerd Schmieta
CPC分类号： B01L9/06 , C12M23/48 , B01L2200/023 , B01L2200/028 , B01L2200/16 , B01L2300/0806
摘要： The present invention describes a base module (100) and a tray insert (200, 300, 400) of a multipurpose tray (100) for an automated processing system, such as an analytical, pre-analytical or post-analytical processing system, as well as to a multipurpose tray comprising such base module and such tray insert, wherein the tray insert can be particularly used for holding a plurality of reagent or sample tubes to be processed in the automated processing system. The present invention further relates to a method of simplified loading/unloading of such a multipurpose tray into/from the automated processing system.
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公开(公告)号：US20230405576A1
公开(公告)日：2023-12-21
申请号：US18031114
申请日：2021-11-01
申请人： BODITECH MED INC.
发明人： Sang Hyun Park , Byeong Chul Kim
IPC分类号： B01L3/02
CPC分类号： B01L3/0275 , B01L2200/026 , B01L2200/023 , B01L3/021
摘要： The present invention relates to a socket for coupling a capillary tip, comprising: a body in which an intra-tubular passage penetrating through both sides thereof is formed, a suction unit of sample collection equipment is provided to be coupled to one side, and a capillary tip is provided to be coupled to the other side; a pressure-varying hole unit which is formed in the body and includes a through hole formed through the intra-tubular passage and the outside of the body; and an opening-and-closing unit which is elastically supported by the pressure-varying hole unit and is installed to close or communicate the through hole and the intra-tubular passage while moving with an elastic force. The present invention can expand the use area for the utilization of capillary tips and can simplify a sample-collecting configuration through the application of manual sampling equipment.
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公开(公告)号：US20230201822A1
公开(公告)日：2023-06-29
申请号：US18083441
申请日：2022-12-16
发明人： Richard COTE
CPC分类号： B01L3/5025 , B01L3/0217 , B01L3/0275 , B01L3/5635 , B01L2200/021 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2300/0829
摘要： An adapter for connecting an array of pipette tips having through bores with conical upper ends to a multichannel air displacement pipettor having a plurality of ports with compliant internal sealing surfaces. The adapter comprises a planar base with an array of openings extending between its top and bottom surfaces. Sealing tubes project upwardly from the top surface, and tip mounting tubes project downwardly from the bottom surface, with pairs of sealing tubes and tip mounting tubes being arranged coaxially and in communication with respective ones of the openings in the base. The tip mounting tubes are externally dimensioned and configured for insertion into the conical upper ends of the pipette tips, and the sealing tubes are externally configured and dimensioned for insertion into the ports of the pipettor and into sealing interengagement with their compliant internal sealing surfaces.
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公开(公告)号：US11679924B2
公开(公告)日：2023-06-20
申请号：US17809788
申请日：2022-06-29
发明人： Tristan Wise , Charles Rhodes
CPC分类号： B65D77/067 , B01L3/52 , B65D83/0077 , B65D83/28 , A61J1/10 , B01L9/04 , B01L9/50 , B01L2200/023 , B01L2200/025 , B01L2200/18 , B01L2300/0848 , B01L2300/123 , B65D2583/005 , B65D2590/0066
摘要： A tube holder assembly includes a base plate, an attachment plate, and an optional securing element. The base plate may include guides into which protrusions of the attachment plate slide to alter the positioning apparatus from an open position to a closed position. The base plate also includes receivers to receive tubular members, which have their movement restrained by the receivers and the securing elements in the closed position. The tube holder assembly may also include a latch to help maintain the closed position during operation.
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公开(公告)号：US20180221864A1
公开(公告)日：2018-08-09
申请号：US15943604
申请日：2018-04-02
申请人： Felix H. Yiu
发明人： Felix H. Yiu
IPC分类号： B01L3/02
CPC分类号： B01L3/0279 , B01L2200/023 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/14
摘要： A mechanism that provides an improved method of loading and unloading a row of disposable pipette tips onto a handheld multichannel pipettor. A single button for tip load and unload operations is simpler than the current method of using a separate mechanism for ejecting the tips. The tips are configured in a rigid collar which is held by a clamp on the pipettor. An upward force combined with a sealing gasket that mates with the top of the pipette tips is used to provide the seal between the tips and the pipettor. This eliminates the requirement to “press downward” with excessive force in order to force the pipette tips onto a protruding sealing part. The loading and unloading of tips will be more reliable and repeatable, this providing better pipetting results. The low forces of the loading and unloading operations reduce the chance of repetitive stress injury for the operator.
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公开(公告)号：US20180148712A1
公开(公告)日：2018-05-31
申请号：US15568475
申请日：2016-02-26
申请人： AJ INNUSCREEN GMBH
发明人： Timo Hillebrand , Thorsten Stroh
IPC分类号： C12N15/10 , C12Q1/6806 , B01L3/02
CPC分类号： C12N15/1006 , B01L3/0275 , B01L2200/023 , B01L2200/0631 , B01L2200/0647 , B01L2300/0854 , B01L2300/16 , C12N15/1013 , C12Q1/6806 , G01N1/405 , G01N35/10
摘要： The invention relates to a method for isolation of nucleic acids from aqueous samples containing nucleic acids in free form or liberated by lysis. Before or after the polarity of the aqueous solution is lowered, the sample is brought into contact with a solid phase that has a rough or structured surface, whereupon the nucleic acids precipitate on the solid phase and then, together with the solid phase, are removed from this aqueous solution. The rough or structured surface is preferably a non-smooth metal, plastic or rubber surface. Subject matter of the invention is also a test kit and a corresponding instrument for isolation of nucleic acids.
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公开(公告)号：US20180133716A1
公开(公告)日：2018-05-17
申请号：US15850087
申请日：2017-12-21
申请人： Hamilton Company
CPC分类号： B01L3/0279 , B01L3/02 , B01L3/0275 , B01L3/563 , B01L2200/02 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/0832 , B01L2300/123 , G01N35/10 , G01N35/1011 , G01N2035/1025 , G01N2035/103
摘要： Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising: circumferentially spaced apart segments, an annular base disposed below the segments and comprising a distal portion, an elastomeric element circumscribing the distal portion, and upwardly extending circumferentially spaced apart arms attached at first ends to the annular base and having upper free ends each supporting a different one of the segments configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between a disk exteriorly disposed about a medial portion of the arms and a stepped interior shoulder of the tip disposed between the first and second working surfaces.
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公开(公告)号：US09937493B1
公开(公告)日：2018-04-10
申请号：US15838811
申请日：2017-12-12
申请人： Hamilton Company
CPC分类号： B01L3/0279 , B01L3/0275 , B01L3/563 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/0832 , B01L2300/123
摘要： Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a first elastomeric element carried by the coupler at a location superior to the coupler shoulder; and a second elastomeric element carried by the coupler at a location inferior to the coupler shoulder wherein the first elastomeric element has a compressed radially expanded state that provides a sealing abutment with a first working surface formed in the interior surface of the pipette tip while compressing the second elastomeric element into sealing abutment with a second working surface formed in the interior surface of the pipette tip and while abutting the proximally facing axial stop surface of the pipette tip with the distally facing axial stop surface of the pipette coupler to define an axial coupling position of the pipette tip on the pipette device.
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公开(公告)号：US09901920B1
公开(公告)日：2018-02-27
申请号：US15793750
申请日：2017-10-25
申请人： Hamilton Company
IPC分类号： B01L3/02
CPC分类号： B01L3/0279 , B01L3/0275 , B01L3/563 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/0832 , B01L2300/123
摘要： Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
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公开(公告)号：US20180043350A1
公开(公告)日：2018-02-15
申请号：US15793750
申请日：2017-10-25
申请人： Hamilton Company
IPC分类号： B01L3/02
CPC分类号： B01L3/0279 , B01L3/0275 , B01L3/563 , B01L2200/023 , B01L2200/025 , B01L2200/026 , B01L2200/04 , B01L2200/0689 , B01L2300/0832 , B01L2300/123
摘要： Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
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