公开(公告)号：US4828840A

公开(公告)日：1989-05-09

申请号：US66512

申请日：1987-06-26

申请人： Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki ,  Kinzaburo Noda ,  Toshiro Fujii

发明人： Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki ,  Kinzaburo Noda ,  Toshiro Fujii

IPC分类号： A61K9/54 ,  A61K9/22 ,  A61K9/50 ,  A61K9/52

CPC分类号： A61K9/5078

摘要： Sustained-release formulations which can release a water-soluble active ingredient or ingredients at the zero-order over a long period of time, comprising:a. an inert core,b. a powder-coating layer containing a water-soluble active ingredient or ingredients,c. a powder-coating layer of practically water-repellent material, andd. a film-coating layer composed of practically pH-independent and water-insoluble film-coating material.

公开(公告)号：US5023089A

公开(公告)日：1991-06-11

申请号：US379631

申请日：1989-07-13

申请人： Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki

发明人： Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki

IPC分类号： A61K9/00 ,  A61K9/16 ,  A61K9/22 ,  A61K9/50

CPC分类号： A61K9/1617 ,  A61K9/5073

摘要： Sustained-release preparations essentially consisting of 1 part by weight of a water-soluble active ingredient and 1 to 10 parts by weight of two or more fats where the melting point is different in one from others, being capable of releasing active ingredients at a constant rate for a long-period of time, and being manufactured easily and economically.

公开(公告)号：US5017380A

公开(公告)日：1991-05-21

申请号：US478278

申请日：1990-02-09

申请人： Yoshio Hamashima ,  Kyoji Minami ,  Kyozo Kawata ,  Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki ,  Masanori Tujikawa

发明人： Yoshio Hamashima ,  Kyoji Minami ,  Kyozo Kawata ,  Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki ,  Masanori Tujikawa

IPC分类号： A61K31/545

CPC分类号： A61K31/545

摘要： An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule and sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.

公开(公告)号：US4933443A

公开(公告)日：1990-06-12

申请号：US275093

申请日：1988-11-21

申请人： Yoshio Hamashima ,  Kyoji Minami ,  Kyozo Kawata ,  Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki ,  Masanori Tujikawa

发明人： Yoshio Hamashima ,  Kyoji Minami ,  Kyozo Kawata ,  Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki ,  Masanori Tujikawa

IPC分类号： A61K9/48 ,  A61K31/545 ,  C07D501/20 ,  C07D501/22

CPC分类号： A61K31/545

摘要： An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule and sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.

公开(公告)号：US4812561A

公开(公告)日：1989-03-14

申请号：US68333

申请日：1987-07-01

申请人： Yoshio Hamashima ,  Kyoji Minami ,  Kyozo Kawata ,  Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki ,  Masanori Tujikawa

发明人： Yoshio Hamashima ,  Kyoji Minami ,  Kyozo Kawata ,  Teruo Sakamoto ,  Toyohiko Takeda ,  Yusuke Suzuki ,  Masanori Tujikawa

IPC分类号： A61K9/48 ,  A61K31/545 ,  C07D501/20 ,  C07D501/22

CPC分类号： A61K31/545

摘要： An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.

摘要翻译： 抗菌的7β-[（Z）-2-（2-氨基噻唑-4-基）-4-羧基丁-2-烯酰氨基] -3-头孢烯-4-羧酸在（二或三） 水合晶体。 将这种水合物的药理学有效量填充在由明胶带密封的明胶硬胶囊中，以在长时间储存​​后制成用于临床使用的稳定组合物。

公开(公告)号：US4720387A

公开(公告)日：1988-01-19

申请号：US617567

申请日：1984-06-05

申请人： Teruo Sakamoto ,  Sadao Kawai ,  Kinzaburo Noda ,  Toyohiko Takeda ,  Toshihiro Ogura

发明人： Teruo Sakamoto ,  Sadao Kawai ,  Kinzaburo Noda ,  Toyohiko Takeda ,  Toshihiro Ogura

IPC分类号： C07D213/75 ,  A61K9/00 ,  A61K9/36 ,  A61K9/50 ,  A61K9/62 ,  A61K31/44 ,  A61K31/4409 ,  A61K9/24

CPC分类号： A61K31/44 ,  A61K9/5084

摘要： Highly effective and orally administrable sustained-release preparation of an antihypertensive agent, pinacidil (N"-cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine) comprising a rapid-release and a slow-release component at a ratio of about 7:3 to about 1:9 by pinacidil weight.

摘要翻译： 高效口服给药的抗高血压药缓释制剂，包含快速释放组分和缓释组分的pinacidil（N“ - 氰基-N-4-吡啶基-N'-1,2,2-三甲基丙基胍） 其比例为约7:3至约1:9。

公开(公告)号：US4713247A

公开(公告)日：1987-12-15

申请号：US615242

申请日：1984-05-30

申请人： Teruo Sakamoto ,  Sadao Kawai ,  Kinzaburo Noda ,  Toyohiko Takeda ,  Hiroshi Kato

发明人： Teruo Sakamoto ,  Sadao Kawai ,  Kinzaburo Noda ,  Toyohiko Takeda ,  Hiroshi Kato

IPC分类号： A61K9/00 ,  A61K9/22 ,  A61K9/48 ,  A61K9/50 ,  A61K9/56 ,  A61K31/545 ,  A61P31/04 ,  A61K9/62 ,  A61K9/58 ,  A61K31/675 ,  A61K31/78

CPC分类号： A61K31/545 ,  A61K9/5084

摘要： Highly potent long-acting formulation of cefaclor for treating bacterial infections in human or animals, comprising a rapid-release and a slow-release component at a ratio of about 3:7 to about 5:5 by potency of cefaclor, convenient for administration or carrying about.

摘要翻译： 用于治疗人或动物中的细菌感染的高效长效制剂，其包含通过头孢克洛的效力以约3:7至约5:5的比例的快速释放和缓释组分，方便给药或 携带

公开(公告)号：US4961527A

公开(公告)日：1990-10-09

申请号：US825951

申请日：1986-02-04

申请人： Teruo Sakamoto

发明人： Teruo Sakamoto

IPC分类号： B41J11/26 ,  B41J11/30

CPC分类号： B41J11/30

摘要： A paper transporting tractor for transporting paper provided with sprocket holes at an equally spaced interval along either side thereof includes a first endless belt having a plurality of sprockets at its outer peripheral surface and a serrated portion at its inner peripheral surface, a driving gear which is in mesh with the serrated portion of the belt thereby causing the belt to move either forward or backward, an end guide portion provided as spaced apart from the driving gear to provide the first endless belt as extended between the gear and the end guide portion and a second endless belt of thin film provided around the end guide portion as sandwiched between the first endless belt and the end guide portion at least partly thereby allowing to substantially decrease the friction between the first endless belt and the end guide portion.

摘要翻译： 用于输送纸张的纸张传送拖拉机沿其两侧间隔间隔地设置有链轮孔，包括在其外周面具有多个链轮的第一环形带和在其内周面的锯齿状部分，驱动齿轮是 与带的锯齿部分啮合，从而使带子向前或向后移动，端部引导部分设置成与驱动齿轮间隔开，以提供在齿轮和端部引导部分之间延伸的第一环形带，以及 在第一环形带和端部引导部之间夹在第一环形带和端部引导部之间，围绕端部引导部分设置的薄膜的第二环形带至少部分地允许基本上减小第一环形带与端部引导部之间的摩擦。

公开(公告)号：US07376577B1

公开(公告)日：2008-05-20

申请号：US09763942

申请日：1999-08-30

申请人： Shinya Yamadera ,  Nobuo Iwamura ,  Naofumi Kutsumi ,  Tadashi Kinoshita ,  Teruo Sakamoto ,  Kenji Mitsuishi ,  Tsutomu Kaneko ,  Shin Fujita ,  Yuichiro Watanabe

发明人： Shinya Yamadera ,  Nobuo Iwamura ,  Naofumi Kutsumi ,  Tadashi Kinoshita ,  Teruo Sakamoto ,  Kenji Mitsuishi ,  Tsutomu Kaneko ,  Shin Fujita ,  Yuichiro Watanabe

IPC分类号： G06F17/60

CPC分类号： G06Q10/06 ,  G06Q10/0631 ,  G06Q10/06393 ,  G06Q10/109

摘要： Apparatuses and methods for managing a process that include schedule management, quality, and process management features. Information is stored on an authorized person in charge and a conformity standard for the work to be managed. From this information, a managing method of the work to be managed from among a plurality of managing methods classified in advance is determined. Processes are determined for each management method, and a time limit determined by the authorized person in charge for each managed process. Adherence standards related to the managed processes are included, as well as records made of the process information including the performance quality of the managed process.

摘要翻译： 用于管理流程的设备和方法，包括进度管理，质量和流程管理功能。 信息存储在授权负责人和要管理的工作的合格标准中。 根据该信息，确定从预先分类的多种管理方法中要管理的工作的管理方法。 确定每个管理方法的流程，以及每个被管理流程的授权负责人确定的时间限制。 包括与管理流程相关的遵守标准，以及由过程信息（包括被管理流程的绩效质量）构成的记录。

公开(公告)号：US4061164A

公开(公告)日：1977-12-06

申请号：US730447

申请日：1976-10-07

申请人： Fumio Sato ,  Teruo Sakamoto ,  Seiichi Watashiro ,  Hayao Inoue ,  Yoshihito Yahata

发明人： Fumio Sato ,  Teruo Sakamoto ,  Seiichi Watashiro ,  Hayao Inoue ,  Yoshihito Yahata

IPC分类号： B65B1/04 ,  B65B1/10 ,  B65B1/28 ,  B65B1/36 ,  B65B43/50 ,  B65B43/58 ,  B65B43/60

CPC分类号： B65B43/60 ,  B65B1/36 ,  B65B1/363

摘要： A composite measure of varying capacity, composed of supplying-aperture of straight cylinder and an inside measure telescopically inserted into the aperture and having a hollow of frusto-conical section, is employed in order to improve accommodation of the known conventional capacity type rotary powder filling machine, to powder of varying bulk density.A turntable which receives the supplying-aperture, superimposes over another turntable which holds the inside measure, and the distance between the both, is adjustable during the operation in accordance with the variance in the bulk density. The height of the container transferring path is also adjustable simultaneously with that of the second turntable.Spouting of compressed-air through an annular nozzle the diameter of which approximates to that of the aperture as a flow parallel to their inside wall is effected to blow off remaining powder in the measure and clean the same when the nozzle is disposed on the aperture.Evacuation for removing air from an empty or partly filled container is made through an annular suction inlet capable of suctioning the air as a flow parallel to the inside wall of the container.

摘要翻译： 采用不同容量的复合尺寸，包括直筒的供应孔径和可伸缩地插入孔中的内部尺寸，并且具有截头圆锥形截面的中空部分，以便改进已知的常规容量型旋转粉末填充物的适应性 机器，不同体积密度的粉末。