摘要:
Sustained-release formulations which can release a water-soluble active ingredient or ingredients at the zero-order over a long period of time, comprising:a. an inert core,b. a powder-coating layer containing a water-soluble active ingredient or ingredients,c. a powder-coating layer of practically water-repellent material, andd. a film-coating layer composed of practically pH-independent and water-insoluble film-coating material.
摘要:
Highly potent long-acting formulation of cefaclor for treating bacterial infections in human or animals, comprising a rapid-release and a slow-release component at a ratio of about 3:7 to about 5:5 by potency of cefaclor, convenient for administration or carrying about.
摘要:
Highly effective and orally administrable sustained-release preparation of an antihypertensive agent, pinacidil (N"-cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine) comprising a rapid-release and a slow-release component at a ratio of about 7:3 to about 1:9 by pinacidil weight.
摘要:
An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule and sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.
摘要:
An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule and sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.
摘要:
An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.
摘要:
Sustained-release preparations essentially consisting of 1 part by weight of a water-soluble active ingredient and 1 to 10 parts by weight of two or more fats where the melting point is different in one from others, being capable of releasing active ingredients at a constant rate for a long-period of time, and being manufactured easily and economically.
摘要:
The centrifugal fluidizing granulator for powder coating granulation has a sensor for detecting changes of viscosity of the growing particles by means of a load cell or a displacement detector; and output signal of the sensor is compared with the data stored in a memory contained in a control unit which determines whether the growing particles are in their wetted state or dried state. The control unit controls the spraying of the liquid and the dispersion of the guest powder based on the result of the comparison.
摘要:
A rotary powder compression machine with a horizontal turntable for compressing powder placed into a compression bore between an upper and a lower compression rods. An ultrasonic sensor monitors the amount of powder deposited upstream of the open feed shoe in the rotation direction of the turn-table.
摘要:
Lead frames supplied from a first supply unit are intermittently conveyed in a non-oxidizing atmosphere. An adhesive is supplied from a second supply unit onto islands of the lead frames, and also semiconductor chips are supplied from a third supply unit onto the islands. When one of different kinds of semiconductor chips supplied from the third supply unit is selected, the selected semiconductor chip is held by a holder having a configuration adapted to the selected semiconductor chip. Therefore, transfer means for semiconductor chips includes at least two kinds of holders.