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1.发明申请公开(公告)号：US20250092468A1
公开(公告)日：2025-03-20
申请号：US18965965
申请日：2024-12-02
Inventor： Min Soo KIM , James BRUGAROLAS , Tae Hyun HWANG , Yang XIE
IPC: C12Q1/6886 , A61P35/00 , C12N15/52 , C40B40/08 , G01N33/50 , G16B25/00 , G16B25/10 , G16B25/20 , G16B30/00 , G16H50/20 , G16H50/30
Abstract: Described herein are methods and systems for identifying and/or treating subjects having cancer who are more likely to respond to treatment with an inhibitor of the transcription factor HIF-2α.
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公开(公告)号：US20180353622A1
公开(公告)日：2018-12-13
申请号：US16003683
申请日：2018-06-08
Inventor： Lawrence LUM , Rubina TULADHAR , Tae Hyun HWANG , Yunku YEU , John Tyler PIAZZA , Quinn BARRETT
CPC classification number: A61K48/0066 , A61K38/465 , C12N15/11 , C12N2310/20
Abstract: Disclosed herein are methods for gene inactivation or rescue by cutting genomic DNA at regions of putative exon splicing enhancers with CRISPR-type enzymes.
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3.发明申请公开(公告)号：US20210222257A1
公开(公告)日：2021-07-22
申请号：US17206895
申请日：2021-03-19
Inventor： Min Soo KIM , James BRUGAROLAS , Tae Hyun HWANG , Yang XIE
IPC: C12Q1/6886 , C12N15/52 , C40B40/08 , G01N33/50 , G16B25/00 , G16H50/30 , G16H50/20 , A61P35/00 , G16B30/00
Abstract: Described herein are methods and systems for identifying and/or treating subjects having cancer who are more likely to respond to treatment with an inhibitor of the transcription factor HIF-2α.
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4.发明申请公开(公告)号：US20190048421A1
公开(公告)日：2019-02-14
申请号：US15761534
申请日：2016-09-16
Inventor： Min Soo KIM , James BRUGAROLAS , Tae Hyun HWANG , Yang XIE
Abstract: Described herein are methods and systems for identifying and/or treating subjects having cancer who are more likely to respond to treatment with an inhibitor of the transcription factor HIF-2α.
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