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公开(公告)号:US20140348865A1
公开(公告)日:2014-11-27
申请号:US14344589
申请日:2012-09-07
申请人: The United States of America, as represented by the Secretary, Department of Health and Human Ser. , University of Maryland, Baltimore , University of Washington
发明人: Peter Kwong , Jason McLellan , Marie Pancera , Jason Gorman , Mallika Sastry , Kaifan Dai , Tongqing Zhou , John Mascola , Gary Nabel , Masaru Kanekiyo , Yongping Yang , Jiang Zhu , Lai-Xi Wang , William Schief , Chris Carrico , Mohammed Amin
IPC分类号: C07K14/005 , C12N7/00
CPC分类号: C07K14/005 , A61K39/12 , A61K39/21 , C12N7/00 , C12N2740/16011 , C12N2740/16034 , C12N2740/16134
摘要: Disclosed are HIV immunogens. Also disclosed are nucleic acids encoding these immunogens and methods of producing these antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a human immunodeficiency type 1 (HIV-1) infection in a subject.
摘要翻译: 披露的是艾滋病毒免疫原。 还公开了编码这些免疫原的核酸和产生这些抗原的方法。 还公开了在受试者中产生免疫应答的方法。 在一些实施方案中,该方法是用于治疗或预防受试者中的人类免疫缺陷1型(HIV-1)感染的方法。