利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

149 条记录 (耗时 0.04 秒)

    Two-membrane medicated device for rate-controlled administration of prostaglandins
    1.
    发明授权
    Two-membrane medicated device for rate-controlled administration of prostaglandins 失效
    用于速率控制前列腺素给药的双膜药物装置

    公开(公告)号：US4237888A

    公开(公告)日：1980-12-09

    申请号：US23126

    申请日：1979-03-23

    申请人： Theodore J. Roseman ,  Osmer C. Carpenter ,  Richard W. Baker ,  James W. Ayres

    发明人： Theodore J. Roseman ,  Osmer C. Carpenter ,  Richard W. Baker ,  James W. Ayres

    IPC分类号： A61F13/20 ,  A61K9/00 ,  A61K31/557

    CPC分类号： A61F13/28 ,  A61F13/2051 ,  A61F13/2068 ,  A61F13/2074 ,  A61K31/557 ,  A61K9/0036 ,  A61F13/2011 ,  A61F2013/8414

    摘要： The present specification describes a medicated device adapted for a single, acute, and rate-controlled rectal or vaginal administration to a mammal of a lipophilic prostaglandin. The device accomplishes drug administration at an essentially time-independent rate of dosage. Further, the device advantageously results in the substantial exhaustion of the prostaglandin from the device at the conclusion of the single, acute use. The device comprises three elements:(A) an inert resilient support means contoured for easy vaginal or rectal insertion;(B) a first flexible polymer film layer affixed to the support means and containing the prostaglandin dispersed therethrough, this first polymer film not being rate limiting as to the release of drug from the device; and(C) a second polymer film, laminated onto the first polymer film and providing a release rate therefrom of prostaglandin, which is rate limiting both as to the release of prostaglandin from the device and absorption rate by the rectal or vaginal tissues.

    摘要翻译： 本说明书描述适用于对亲脂性前列腺素的哺乳动物的单次，急性和速率控制的直肠或阴道给药的药物装置。 该装置以基本上时间独立的剂量速率实现药物给药。 此外，该装置有利地导致在单次急性使用结束时来自装置的前列腺素的显着耗尽。 该装置包括三个元件：（A）易于阴道或直肠插入的惰性弹性支撑装置; （B）固定在支撑装置上并含有分散在其中的前列腺素的第一柔性聚合物膜层，该第一聚合物膜不限制药物从装置中的释放; 和（C）第二聚合物膜，层压在第一聚合物膜上并提供前列腺素的释放速率，前列腺素的释放速率限于前列腺素从装置中的释放和由直肠或阴道组织吸收的速率。

    Two-member medicated device for rate-controlled administration of lipophilic pharmaceuticals
    2.
    发明授权
    Two-member medicated device for rate-controlled administration of lipophilic pharmaceuticals 失效
    用于脂质药物速率控制的双组分药物装置

    公开(公告)号：US4308867A

    公开(公告)日：1982-01-05

    申请号：US23125

    申请日：1979-03-23

    申请人： Theodore J. Roseman ,  Osmer S. Carpenter ,  Richard W. Baker ,  James W. Ayres

    发明人： Theodore J. Roseman ,  Osmer S. Carpenter ,  Richard W. Baker ,  James W. Ayres

    IPC分类号： A61K9/48 ,  A61F13/20 ,  A61K9/00 ,  A61K31/557 ,  A61M7/00

    CPC分类号： A61F13/28 ,  A61F13/2051 ,  A61F13/2068 ,  A61F13/2074 ,  A61K31/557 ,  A61K9/0036 ,  A61F13/2011 ,  Y10S604/904

    摘要： The present specification describes a medicated device adapted for a single and rate-controlled rectal or vaginal administration to a mammal of a systemically active pharmaceutical (SAP). The device accomplishes drug administration at an essentially time-independent rate of dosage. Further, the device advantageously results in the substantial exhaustion of the SAP from the device at the conclusion of the single, acute use. The device comprises three elements:(A) an inert resilient support means contoured for easy vaginal or rectal insertion;(B) a first flexible polymer film layer affixed to the support means and containing the SAP dispersed therethrough, this first polymer film not being rate limiting as to the release of drug from the device; and(C) a second polymer film, laminated onto the first polymer film and providing a release rate therefrom of prostaglandin, which is rate limiting both as to the release of prostaglandin from the device and absorption rate by the rectal or vaginal tissues.

    摘要翻译： 本说明书描述了一种适用于单一和速率控制的直肠或阴道给药的药物装置，其用于系统活性药物（SAP）的哺乳动物。 该装置以基本上时间独立的剂量速率实现药物给药。 此外，该装置有利地导致在单次急性使用结束时SAP从装置中显着耗尽。 该装置包括三个元件：（A）易于阴道或直肠插入的惰性弹性支撑装置; （B）第一柔性聚合物膜层，其固定在支撑装置上并含有分散在其中的SAP，该第一聚合物膜不能限制药物从装置中的释放; 和（C）第二聚合物膜，层压在第一聚合物膜上并提供前列腺素的释放速率，前列腺素的释放速率限于前列腺素从装置中的释放和由直肠或阴道组织吸收的速率。

    MEMBRANE LOOP PROCESS FOR SEPARATING CARBON DIOXIDE FOR USE IN GASEOUS FORM FROM FLUE GAS
    8.
    发明申请
    MEMBRANE LOOP PROCESS FOR SEPARATING CARBON DIOXIDE FOR USE IN GASEOUS FORM FROM FLUE GAS 有权
    用于分离二氧化碳的膜循环过程用于来自气体气体的气体形式

    公开(公告)号：US20110260112A1

    公开(公告)日：2011-10-27

    申请号：US13123364

    申请日：2010-09-13

    申请人： Johannes G. Wijmans ,  Richard W. Baker ,  Timothy C. Merkel

    发明人： Johannes G. Wijmans ,  Richard W. Baker ,  Timothy C. Merkel

    IPC分类号： C01B31/20

    CPC分类号： B01D53/22 ,  B01D53/62 ,  B01D2256/22 ,  B01D2257/504 ,  B01D2311/13 ,  F23J15/006 ,  F23J15/02 ,  F23J2215/50 ,  F23J2219/00 ,  F23L7/007 ,  Y02C10/04 ,  Y02C10/08 ,  Y02C10/10 ,  Y02C20/20 ,  Y02E20/326 ,  Y02E20/344

    摘要： The invention is a process involving membrane-based gas separation for separating and recovering carbon dioxide emissions from combustion processes in partially concentrated form, and then transporting the carbon dioxide and using or storing it in a confined manner without concentrating it to high purity. The process of the invention involves building up the concentration of carbon dioxide in a gas flow loop between the combustion step and a membrane separation step. A portion of the carbon dioxide-enriched gas can then be withdrawn from this loop and transported, without the need to liquefy the gas or otherwise create a high-purity stream, to a destination where it is used or confined, preferably in an environmentally benign manner.

    摘要翻译： 本发明是一种涉及膜基气体分离的方法，用于从部分浓缩形式的燃烧过程中分离和回收二氧化碳排放，然后运输二​​氧化碳并以密闭方式使用或储存，而不将其浓缩至高纯度。 本发明的方法涉及在燃烧步骤和膜分离步骤之间建立气流回路中二氧化碳的浓度。 然后可以将一部分富含二氧化碳的气体从该回路中排出并运输，而不需要将气体液化或以其它方式产生高纯度物流到其使用或限制的目的地，优选地以环境友好 方式。