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1.发明授权公开(公告)号：US07744538B2
公开(公告)日：2010-06-29
申请号：US10979584
申请日：2004-11-01
IPC分类号： A61B8/00
CPC分类号： G01S15/8979 , A61B8/06 , A61B8/13 , G01S7/5206 , Y10S128/916
摘要： Minimum arc interpolation is performed on velocity information distributed in three dimensions. By using complex representations of the velocity information, the interpolation may more accurately represent the angle or velocity for spatial conversion. Tri-linearly interpolating velocity information converts the information representing a three-dimensional volume to a reconstruction grid. The interpolation is performed with a graphics processing unit. Complex representations of the velocity are loaded as texture data. The graphics processing unit interpolates the data as texture fields. Look-up tables are used to determine an angle from the interpolated complex representation and/or a color value for displaying velocities associated with different spatial locations.
摘要翻译： 对三维分布的速度信息执行最小弧插补。 通过使用速度信息的复杂表示，插值可以更精确地表示用于空间转换的角度或速度。 三线性内插速度信息将表示三维体积的信息转换成重建网格。 用图形处理单元执行插值。 速度的复杂表示作为纹理数据加载。 图形处理单元将数据内插为纹理区域。 查找表用于从内插复数表示中确定角度和/或用于显示与不同空间位置相关联的速度的颜色值。
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2.发明申请公开(公告)号：US20130294665A1
公开(公告)日：2013-11-07
申请号：US13461109
申请日：2012-05-01
申请人： Bimba Rao , Ismayil M. Guracar , Kutay F. Ustuner
发明人： Bimba Rao , Ismayil M. Guracar , Kutay F. Ustuner
IPC分类号： G06K9/00
CPC分类号： G01S15/8995 , G01S15/8977
摘要： Steered spatial compounding is provided in ultrasound imaging. Component frames of data associated with different spatial response are processed to identify different sources of signals. Matched filtering and/or spatial variance with erosion distinguish between sources of signals, such as distinguishing between (1) anatomical structure and (2) soft tissue and/or noise. The locations in the patient are segmented by the source of signals and different compounding is applied for the different sources.
摘要翻译： 在超声成像中提供了转向空间复合。 处理与不同空间响应相关联的数据的分量帧，以识别不同的信号源。 具有侵蚀的匹配滤波和/或空间方差区分信号源，例如区分（1）解剖结构和（2）软组织和/或噪声。 患者中的位置由信号源分段，不同的复合应用于不同的来源。
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公开(公告)号：US07998076B2
公开(公告)日：2011-08-16
申请号：US11237221
申请日：2005-09-27
CPC分类号： G01S15/8981 , A61B8/481 , G01S7/52039
摘要： Contrast agents are characterized with ultrasound. Flowing or unbound contrast agents are distinguished automatically from bound or relatively stationary contrast agents. The bound or relatively stationary contrast agents are highlighted on a display. A processor distinguishes different types of contrast agents or contrast agents in different binding states with relative signal strength or velocity. Attached contrast agents are differentiated from phagocytosed contrast agents. Monitoring absolute signal strength as a function of time may indicate binding. Any one or more of these features may be used.
摘要翻译： 造影剂用超声波表征。 流动或未结合的造影剂自动与界定或相对静止的造影剂区分开。 绑定或相对静止的造影剂在显示器上突出显示。 处理器将不同类型的造影剂或造影剂以相对信号强度或速度区别在不同的结合状态。 附着的造影剂与吞噬的造影剂不同。 监测绝对信号强度作为时间的函数可能表示绑定。 可以使用这些特征中的一个或多个。
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公开(公告)号：US07993273B2
公开(公告)日：2011-08-09
申请号：US12129544
申请日：2008-05-29
IPC分类号： A61B8/14
摘要： System parameters for contrast agent medical imaging are conveniently set. A simplified contrast agent configuration is provided where an appropriate contrast agent detection technique and/or contrast agent imaging parameters are achieved consistently and more often then exists with current methods. Examination workflow is improved for contrast agent studies by offering one contrast agent imaging mode or configuration that is dynamically determined and optimized based on the user's selected transmit level and/or a real-time measurement of the contrast agent signals. A simplified user interface provides one contrast agent imaging mode without a need to switch between multiple modes or contrast agent detection techniques and associated contrast agent imaging parameters. The contrast agent detection technique and imaging parameters are adjusting or selected based on changes in the transmit levels for contrast agent imaging. Either a single user input control or real time measurements are used to select a transmit level, resulting in automatic selection of adjustment of the detection technique and/or imaging parameters. Appropriate contrast agent detection techniques and imaging parameters are selected for each given transmit level without the user having to switch the mode or configuration of the system during an imaging session. As a result, contrast agent examinations are simplified while minimizing suboptimal selection by a user.
摘要翻译： 造影剂医学成像的系统参数设置方便。 提供了一种简化的造影剂配置，其中一致地实现适当的造影剂检测技术和/或造影剂成像参数，并且随后以当前方法存在。 通过提供基于用户选择的发射电平和/或造影剂信号的实时测量动态确定和优化的一种造影剂成像模式或配置，对造影剂研究的检查工作流程得到改善。 简化的用户界面提供一种造影剂成像模式，而无需在多种模式或造影剂检测技术和相关的造影剂成像参数之间进行切换。 造影剂检测技术和成像参数根据造影剂成像的传输水平的变化进行调整或选择。 使用单个用户输入控制或实时测量来选择发射电平，导致自动选择检测技术和/或成像参数的调整。 为每个给定的传输级别选择适当的造影剂检测技术和成像参数，而用户不必在成像会话期间切换系统的模式或配置。 因此，简化了造影剂检查，同时使用户的次优选择最小化。
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公开(公告)号：US20110016977A1
公开(公告)日：2011-01-27
申请号：US12780688
申请日：2010-05-14
申请人： Ismayil M. Guracar
发明人： Ismayil M. Guracar
CPC分类号： G01N29/0654 , A61B8/483 , A61B8/54 , G01N29/245 , G01N29/262 , G01S7/52085 , G01S15/8925 , G01S15/8927
摘要： A plane or volume is scanned with ultrasound. Electronic movement of apertures is used during the scanning. Scanning with the apertures is interleaved. The apertures move along the array in opposite directions, preventing or limiting large temporal discontinuity. For example, two apertures begin at similar angles on a two-dimensional array. Planar scans are performed for each aperture location. The apertures are counter rotated (i.e., one clockwise and the other counter clockwise).
摘要翻译： 用超声扫描平面或体积。 在扫描期间使用孔的电子移动。 用孔扫描是交错的。 孔径沿相反方向沿着阵列移动，防止或限制大的时间不连续性。 例如，两个孔以二维阵列上的相似角度开始。 对每个光圈位置执行平面扫描。 孔被反向旋转（即，一个顺时针和另一个逆时针旋转）。
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6.发明申请Synchronized combining for contrast agent enhanced medical diagnostic ultrasound imaging 审中-公开同步组合造影剂增强医学诊断超声成像公开(公告)号：US20090187106A1
公开(公告)日：2009-07-23
申请号：US12011178
申请日：2008-01-23
申请人： Chi-Yin Lee , Ismayil M. Guracar , Helene C. Houle
发明人： Chi-Yin Lee , Ismayil M. Guracar , Helene C. Houle
IPC分类号： A61B8/00
CPC分类号： A61B8/5276 , A61B8/0883 , A61B8/481 , G01S7/52088 , G01S15/108 , G01S15/8963 , G06T5/50 , G06T2207/20221
摘要： Contrast agent enhanced medical diagnostic imaging is provided. Frames of data from common phase periods are grouped. Motion correction is performed within each common phase group. An image representing contrast agents is formed from a combination of the frames within each common phase, motion corrected group.
摘要翻译： 提供对比剂增强的医学诊断成像。 来自公共相位周期的数据帧被分组。 运动校正在每个公共相位组内进行。 代表造影剂的图像由每个公共相位，运动校正组中的帧的组合形成。
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公开(公告)号：US20090012400A1
公开(公告)日：2009-01-08
申请号：US12234448
申请日：2008-09-19
IPC分类号： A61B8/14
摘要： Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of contrast-to-tissue specificity, ultrasound based 3D contrast agent based coronary artery angiograms may be possible. Measurement and display of the velocity of agent from the cubic fundamental signal is provided simultaneously with display of cubic fundamental energy, such as providing a display map indexed by both energy and velocity. High pulse repetition frequency (PRF) for cubic fundamental detection in conjunction with long velocity measurement intervals may increase low velocity sensitivity and measurement precision. Pulsed wave (PW) Doppler may be improved by using a cubic fundamental sensitive pulse sequence. Using cubic fundamental sensitive techniques with other motion estimation techniques, such as two-dimensional velocity estimation or speckle tracking, may operate better than using other contrast agent detection techniques because of substantially reduced clutter.
摘要翻译： 可以通过处理立方基本信息来获得容器中诸如冠状动脉之间的流动的高度特异性测量。 通过显示具有高度对比组织特异性的血管中的流动，基于超声的基于3D造影剂的冠状动脉血管造影可能是可能的。 与三次基本能量的显示同时提供来自三次基本信号的试剂速度的测量和显示，例如提供由能量和速度两者分度的显示图。 结合长速度测量间隔的三次基波检测的高脉冲重复频率（PRF）可以提高低速度灵敏度和测量精度。 脉冲波（PW）多普勒可以通过使用立方基本敏感脉冲序列来改善。 使用三维基本敏感技术与其他运动估计技术（如二维速度估计或斑点跟踪）相比，使用其他造影剂检测技术的操作可能比实际上减少的杂波更好。
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8.发明申请Inter-frame processing for contrast agent enhanced medical diagnostic ultrasound imaging 审中-公开造影剂的帧间处理增强了医学诊断超声成像公开(公告)号：US20080214934A1
公开(公告)日：2008-09-04
申请号：US11713209
申请日：2007-03-02
申请人： Chi-Yin Lee , James E. Chomas , Ismayil M. Guracar
发明人： Chi-Yin Lee , James E. Chomas , Ismayil M. Guracar
IPC分类号： A61B8/00
CPC分类号： A61B8/5276 , A61B8/481
摘要： Contrast agent enhanced medical diagnostic imaging is improved by selecting particular frames of data. Frames of data are acquired over time. Information from the frames of data are combined, such as for a time intensity curve or maximum intensity processing. Rather than combining information from each of the frames, information from some frames is not used. Frames are selected for inclusion. In one embodiment, the selection is based on one type of data (e.g., B-mode) for combining information for another type of data (e.g., contrast agent data).
摘要翻译： 通过选择特定的数据帧来改善对比剂增强的医疗诊断成像。 随着时间的推移，获取数据帧。 来自数据帧的信息被组合，例如用于时间强度曲线或最大强度处理。 不是组合来自每个帧的信息，而是不使用来自某些帧的信息。 选择框架进行包含。 在一个实施例中，所述选择基于用于组合用于另一类型数据（例如造影剂数据）的信息的一种类型的数据（例如，B模式）。
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公开(公告)号：US07004906B1
公开(公告)日：2006-02-28
申请号：US10899803
申请日：2004-07-26
IPC分类号： A61B8/00
摘要： Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of contrast-to-tissue specificity, ultrasound based 3D contrast agent based coronary artery angiograms may be possible. Measurement and display of the velocity of agent from the cubic fundamental signal is provided simultaneously with display of cubic fundamental energy, such as providing a display map indexed by both energy and velocity. High pulse repetition frequency (PRF) for cubic fundamental detection in conjunction with long velocity measurement intervals may increase low velocity sensitivity and measurement precision. Pulsed wave (PW) Doppler may be improved by using a cubic fundamental sensitive pulse sequence. Using cubic fundamental sensitive techniques with other motion estimation techniques, such as two-dimensional velocity estimation or speckle tracking, may operate better than using other contrast agent detection techniques because of substantially reduced clutter.
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公开(公告)号：US06497666B1
公开(公告)日：2002-12-24
申请号：US09696511
申请日：2000-10-25
IPC分类号： A61B814
CPC分类号： A61B8/481 , A61B8/14 , G01S7/52034 , G01S7/52041 , G01S7/52046 , G01S7/5206 , G01S7/52074 , G01S15/8981
摘要： A medical ultrasonic imaging system transmits a set of two or more substantially identical transmit pulses into a tissue containing a contrast agent. The associated received pulses are filtered with a broadband filter that passes both the fundamental and at least one harmonic component of the echoes. The filtered received pulses are then applied to a clutter filter that suppresses harmonic and fundamental responses from slowly moving and stationary tissue, while clearly showing contrast agent response due to the loss of correlation effect. The disclosed system includes other signal paths for generating conventional B-mode images as well as combined images that include both components from the contrast-specific image as well as components from the B-mode image. An improved user interface allows the user to switch among these three images. Preferably the transmitter generates transmitted pulses having two or more spatially distinct focus zones, thereby improving the uniformity of contrast agent imaging over the imaged region.
摘要翻译： 医疗超声成像系统将一组两个或更多基本相同的发射脉冲发送到包含造影剂的组织中。 相关联的接收脉冲用宽带滤波器滤波，该滤波器通过回波的基波和至少一个谐波分量。 滤波的接收脉冲然后被施加到杂波滤波器，其抑制来自缓慢移动和静止组织的谐波和基波响应，同时由于相关效应的损失而清楚地显示造影剂响应。 所公开的系统包括用于产生常规B模式图像的其他信号路径以及包括来自对比度特定图像的两个组件以及来自B模式图像的组件的组合图像。 改进的用户界面允许用户在这三个图像之间切换。 优选地，发射器产生具有两个或更多个空间上不同的聚焦区域的发射脉冲，从而改善造影剂成像在成像区域上的均匀性。
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