公开(公告)号：US20060079949A1

公开(公告)日：2006-04-13

申请号：US10963184

申请日：2004-10-12

申请人： Thomas Brostrom ,  Ryan Bauer ,  Douglas Hine

发明人： Thomas Brostrom ,  Ryan Bauer ,  Douglas Hine

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/057 ,  A61N2001/0578

摘要： A lead stabilization and extension wire that enables the withdrawal of a guide catheter over an electrical medical lead body without dislodging an electrode or sensor from an implantation site or detaching the fixation mechanism and methods of use and a kit are disclosed. The lead stabilizer and retraction wire comprises a wire sheath and an elongated core wire insertable within a sheath lumen. The sheath is insertable within a lead body lumen and includes a movable lead clamp that can engage with a lead connector element and a friction element frictionally engaging the core wire to maintain the extension wire length. The lead stabilizer and retraction wire is insertable into the lead body lumen enabling retraction of the guide catheter over the lead stabilization and extension wire while force is applied through the lead stabilization and extension wire to maintain the distal electrode at the implantation site.

摘要翻译： 公开了一种引线稳定和延伸线，其能够引导导管在电学医疗引线主体上取出，而不会从植入部位移除电极或传感器，或者分离固定机构以及使用方法和试剂盒。 引线稳定器和回缩线包括线鞘和可插入鞘管内的细长芯线。 护套可插入引线体腔内并且包括可移动引线夹，其可与引线连接器元件接合，摩擦元件与芯线摩擦接合以保持延长线长度。 引导稳定器和收回线可插入引线体腔，从而能够使引导导管缩回到引线稳定和延伸线上，同时通过引线稳定和延伸线施加力，以将远端电极保持在植入位置。

公开(公告)号：US20050090870A1

公开(公告)日：2005-04-28

申请号：US10692647

申请日：2003-10-24

申请人： Douglas Hine ,  Ven Manda ,  John Sommer

发明人： Douglas Hine ,  Ven Manda ,  John Sommer

IPC分类号： A61B5/042 ,  A61B5/0464 ,  A61N1/05 ,  A61N1/365

CPC分类号： A61N1/0587 ,  A61B5/0422 ,  A61B5/0464 ,  A61N1/056 ,  A61N1/36514 ,  A61N2001/0585 ,  G06F19/00

摘要： The present invention provides a method and apparatus for assessing ventricular function on a chronic basis using a plurality of electrodes disposed on or about a left ventricle and/or a right ventricle—and optionally, at least one mechanical or metabolic sensor—all operatively electrically coupled to an implantable medical device. The plurality of electrodes are preferably spaced-apart so that at least one electrode is disposed electrical communication with a discrete volume of ventricular tissue. In one embodiment, the discrete volume of tissue is defined by multiple longitudinal and axial planes as known and used in the medical arts. Thus, according to the present invention, at least one electrode couples to appropriate sensing circuitry and essentially provides a localized electrogram (EGM) that, when compared to other EGMs, provides for configurable, localized delivery of therapeutic pacing stimulus, diverse impedance-sensing vectors, various diagnostic information regarding myocardial function and/or anti-tachycardia pacing.

摘要翻译： 本发明提供一种用于使用设置在左心室和/或右心室上的周围的多个电极以及任选地至少一个机械或代谢传感器来长期地评估心室功能的方法和装置，所述多个电极全部可操作地电耦合 到可植入医疗装置。 多个电极优选间隔开，使得至少一个电极与离散体积的心室组织电连通。 在一个实施例中，组织的离散体积由医学领域中已知和使用的多个纵向和轴向平面限定。 因此，根据本发明，至少一个电极耦合到适当的感测电路并且基本上提供局部电描记图（EGM），其与其他EGM相比，提供治疗起搏刺激的可配置的局部递送，各种阻抗感测向量 ，关于心肌功能和/或抗心动过速起搏的各种诊断信息。

公开(公告)号：US20050288761A1

公开(公告)日：2005-12-29

申请号：US10876003

申请日：2004-06-24

申请人： Scott Brabec ,  Douglas Hine

发明人： Scott Brabec ,  Douglas Hine

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N2001/0585

摘要： A pacing lead includes a first pacing cathode coupled to a first conductor, a second pacing cathode coupled to a second conductor, and a flexible anode coupled to a third conductor. The flexible anode has a length less than approximately 10 millimeters and is spaced apart from and proximal to the first pacing cathode and spaced apart from and distal to the second pacing cathode. The spacing between the anode and the first pacing cathode is approximately equal to the spacing between the anode and the second pacing cathode.

摘要翻译： 起搏引线包括耦合到第一导体的第一起搏阴极，耦合到第二导体的第二起搏阴极和耦合到第三导体的柔性阳极。 柔性阳极具有小于约10毫米的长度，并且与第一起搏阴极间隔开并靠近第一起搏阴极并与第二起搏阴极间隔开并远离第二起搏阴极。 阳极和第一起搏阴极之间的间隔大致等于阳极和第二起搏阴极之间的间隔。

公开(公告)号：US20050033371A1

公开(公告)日：2005-02-10

申请号：US10635166

申请日：2003-08-06

申请人： John Sommer ,  Douglas Hine ,  Douglas Hess

发明人： John Sommer ,  Douglas Hine ,  Douglas Hess

IPC分类号： A61N1/375

CPC分类号： A61N1/3752

摘要： A connector sleeve includes a lumen adapted to receive a medical lead connector wherein a retention element engages a retention edge formed at a distal end of a connector element included on the lead connector. The connector sleeve further includes a contact element adapted to electrically engage the lead connector element within the lumen and an external conductive surface electrically coupled to the contact element and adapted for electrical engagement within the connector bore of an implantable medical device.

摘要翻译： 连接器套管包括适于接收医疗引线连接器的内腔，其中保持元件接合形成在包括在引线连接器上的连接器元件的远端处的保持边缘。 连接器套筒还包括适于电连接腔内的引线连接器元件的接触元件和电耦合到接触元件的外部导电表面，并且适于电连接在可植入医疗器械的连接器孔内。

公开(公告)号：US05999858A

公开(公告)日：1999-12-07

申请号：US196860

申请日：1998-11-20

申请人： John L. Sommer ,  Rick D. McVenes ,  Douglas Hine

发明人： John L. Sommer ,  Rick D. McVenes ,  Douglas Hine

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N2001/0585

摘要： A cardiac pacing lead for use in the coronary sinus and coronary veins. The lead is provided with a lead body configured to exhibit a curved configuration along a distal portion thereof, induced to maintain a portion of the curved configuration solely by a portion of a polyurethane lead body formed to display the curved configuration and wherein the lead conductor is freely mounted within the segment The curved configuration includes first and second arcuate segments together providing a single-plane curvature of approximately 180 degrees, separated by a generally straight segment, the first segment having a greater length and greater arc of curvature than the second segment. The lead body encloses a first conductive coil coupled to an electrode mounted to the distal end of the lead body and a second elongated conductive coil is also located within the lead body and extends to a transition point proximal to the distal end of the first coil conductor, the second coil terminating within the lead body and insulated from the exterior of the lead body. The first conductive coil has a generally straight configuration and the distal portion of the second coil is formed to define a curve.

摘要翻译： 用于冠状窦和冠状静脉的心脏起搏导联。 引线设置有引线主体，其被构造成沿着其远端部分呈现弯曲构造，被引导以仅保持弯曲构造的一部分由形成为显示弯曲构造的聚氨酯引线体的一部分，并且其中引线导体为 自由地安装在段内弯曲构造包括第一和第二弓形段，其一起提供大致180度的单平面曲率，由大致直的段分开，第一段具有比第二段更大的长度和更大的曲率弧。 引线体包围耦合到安装到引线主体的远端的电极的第一导电线圈，并且第二细长导电线圈也位于引线主体内并且延伸到靠近第一线圈导体的远端的过渡点 ，所述第二线圈终止于所述引线体内并与所述引线体的外部绝缘。 第一导电线圈具有大致直的构造，并且第二线圈的远端部分形成为限定曲线。

公开(公告)号：US20050043771A1

公开(公告)日：2005-02-24

申请号：US10646899

申请日：2003-08-21

申请人： John Sommer ,  Douglas Hine

发明人： John Sommer ,  Douglas Hine

IPC分类号： A61N1/375 ,  H01R13/52 ,  H01R27/00 ,  H01R31/06

CPC分类号： H01R31/06 ,  A61N1/3752 ,  H01R13/5224 ,  H01R27/00 ,  H01R2201/12

摘要： A lead connector is terminated proximally by a connector pin and includes a circumferential array of connector pads, each connector pad coupled to an electrode via an elongated insulated conductor. A lumen of an adaptor is adapted to engage the lead connector and includes an electrical contact zone formed therein and positioned for coupling with a one of the array of connector pads, when the connector is engaged within the lumen, in order to facilitate electrical connection of a selected electrode corresponding to the one of the array of connector pads.

摘要翻译： 引线连接器由连接器针靠近端接，并且包括连接器焊盘的圆周阵列，每个连接器焊盘通过细长的绝缘导体耦合到电极。 适配器的内腔适于接合引线连接器并且包括形成在其中的电接触区域，并且当连接器接合在内腔内时，该内部定位成与连接器焊盘阵列中的一个连接，以便于电连接 选择的电极对应于所述连接器焊盘阵列中的一个。

公开(公告)号：US20050043770A1

公开(公告)日：2005-02-24

申请号：US10646545

申请日：2003-08-21

申请人： Douglas Hine ,  John Sommer ,  John Gurley

发明人： Douglas Hine ,  John Sommer ,  John Gurley

IPC分类号： H01R13/52 ,  H01R31/06 ,  A61N1/375

CPC分类号： H01R13/5224 ,  H01R31/06

摘要： A lead connector including a connector element array is fitted into a selected adaptor from a plurality of adaptors to electrically couple one or more elements of the connector element array, corresponding to one or more selected electrodes from an array of lead electrodes, to one or more contact zones of the selected adaptor in order to facilitate electrical connection with an implantable medical device.

摘要翻译： 将包括连接器元件阵列的引线连接器从多个适配器装配到所选择的适配器中，以将来自引线电极阵列的一个或多个所选电极的连接器元件阵列的一个或多个元件电耦合到一个或多个 接触区域，以便于与可植入医疗设备的电连接。

公开(公告)号：US6144882A

公开(公告)日：2000-11-07

申请号：US895977

申请日：1997-07-17

申请人： John L. Sommer ,  Rick D. McVenes ,  Douglas Hine

发明人： John L. Sommer ,  Rick D. McVenes ,  Douglas Hine

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N2001/0585

摘要： A cardiac pacing lead for use in the coronary sinus and coronary veins. The lead is provided with a lead body configured to exhibit a curved configuration along a distal portion thereof, induced to maintain a portion of the curved configuration solely by means of a portion of a polyurethane lead body formed to display the curved configuration and wherein the lead conductor is freely mounted within the segment. The curved configuration includes first and second arcuate segments together providing a single-plane curvature of approximately 180 degrees, separated by a generally straight segment, the first segment having a greater length and greater arc of curvature than the second segment. The lead body encloses a first conductive coil coupled to an electrode mounted to the distal end of the lead body and a second elongated conductive coil is also located within the lead body and extends to a transition point proximal to the distal end of the first coil conductor, the second coil terminating within the lead body and insulated from the exterior of the lead body. The first conductive coil has a generally straight configuration and the distal portion of the second coil is formed to define a curve.

摘要翻译： 用于冠状窦和冠状静脉的心脏起搏导联。 引线设置有引线主体，其被构造成沿着其远端部分呈现弯曲的构造，被引导以仅通过形成为显示弯曲构造的聚氨酯引线体的一部分来维持弯曲构造的一部分，并且其中引线 导体自由地安装在片段内。 弯曲构造包括第一和第二弓形段，其一起提供大致180度的单平面曲率，由大致直的段分开，第一段具有比第二段更大的长度和更大的曲率弧。 引线体包围耦合到安装到引线主体的远端的电极的第一导电线圈，并且第二细长导电线圈也位于引线主体内并且延伸到靠近第一线圈导体的远端的过渡点 ，所述第二线圈终止于所述引线体内并与所述引线体的外部绝缘。 第一导电线圈具有大致直的构造，并且第二线圈的远端部分形成为限定曲线。

公开(公告)号：US20060292912A1

公开(公告)日：2006-12-28

申请号：US11468910

申请日：2006-08-31

申请人： Vicki Bjorklund ,  John Sommer ,  Douglas Hine ,  Charles Love ,  Douglas Heiss ,  Nicolaas Lokhoff

发明人： Vicki Bjorklund ,  John Sommer ,  Douglas Hine ,  Charles Love ,  Douglas Heiss ,  Nicolaas Lokhoff

IPC分类号： H01R11/22

CPC分类号： A61N1/056 ,  A61N1/057 ,  A61N2001/058

摘要： An improved medical lead assembly and method of use is provided. The lead assembly includes a lead body, and a spring member positioned adjacent to the lead body. The spring member may be deployed a selectable amount to maintain the lead body in a fixed location within a patient's body. The spring member may be an expandable coil, a mesh structure that is similar to a stent, or any other similar device that may be positioned in a low-profile state during a lead implant procedure. After the lead is positioned at a target destination, the spring member may be deployed an amount that is selected based on the characteristics of the surrounding tissue, including vessel size. According to one aspect of the invention, the lead assembly may provide means for facilitating chronic lead extraction.

摘要翻译： 提供了一种改进的医疗引线组件和使用方法。 引线组件包括引线体和邻近引线体定位的弹簧部件。 弹簧构件可以部署可选择的量以将引线体保持在患者体内的固定位置。 弹簧构件可以是可扩张线圈，类似于支架的网状结构或者在引线植入过程期间可以被定位在低轮廓状态的任何其它类似的装置。 在引线定位在目标目的地之后，弹簧构件可以展开一定量，该量基于包括容器尺寸的周围组织的特性来选择。 根据本发明的一个方面，引线组件可以提供用于促进慢性铅提取的装置。

公开(公告)号：US20060247692A1

公开(公告)日：2006-11-02

申请号：US11116547

申请日：2005-04-28

申请人： Zhongping Yang ,  Mark Hjelle ,  Douglas Hine

发明人： Zhongping Yang ,  Mark Hjelle ,  Douglas Hine

IPC分类号： A61N1/362

CPC分类号： A61N1/36557 ,  A61N1/056 ,  A61N1/3627 ,  A61N1/36564

摘要： In some embodiments, a method for optimizing cardiac resynchronization therapy (CRT) may include one or more of the following steps: (a) conducting a baseline measurement of a physical parameter of a patient before initiating CRT, (b) performing an implantation process including implanting a pacing device and pacing leads in the patient, the pacing device and pacing leads for providing the CRT, (c) initiating CRT on the patient, (d) measuring the physical parameter of the patient after initiation of the CRT, (e) comparing the measured physical parameter after initiation of the CRT to the baseline measure of the physical parameter to analyze the patient's response to the CRT, (f) adjusting the CRT during the implantation process to try and improve the patient's response to the CRT, and (g) repositioning at least one of the patient leads during the implantation process to try and improve the patient's response to the CRT.

摘要翻译： 在一些实施例中，用于优化心脏再同步治疗（CRT）的方法可以包括以下步骤中的一个或多个：（a）在开始CRT之前对患者的物理参数进行基线测量，（b）执行植入过程，包括 将起搏装置和起搏引线植入患者体内，起搏装置和起搏引线用于提供CRT，（c）在患者身上启动CRT，（d）在CRT开始后测量患者的物理参数，（e） 将CRT开始后的测量物理参数与物理参数的基线测量进行比较，以分析患者对CRT的反应，（f）在植入过程中调整CRT以尝试改善患者对CRT的反应，和 g）在植入过程期间重新定位至少一个患者导线，以试图改善患者对CRT的反应。