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公开(公告)号：US07996090B2
公开(公告)日：2011-08-09
申请号：US11742449
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： Implantable medical leads and methods of making. The method includes providing first and second tubes, and arranging a segment of the first tube side-by-side with a segment of the second tube along a region of interface. The tubes are forced to a non-linear shape along at least a portion of the region of interface. An adhesive is applied to the portion of the region of interface and cured. Upon curing, the adhesive bonds the tubes to one another and elastically maintains the non-linear shape in the absence of an external force. A conductive element is disposed within at least one of the tubes. In some embodiments, the non-linear shape is a sigmoid shape, and the method includes arranging the tube segments in a fixture having a structure defining the sigmoid shape.
摘要翻译： 植入式医疗线索和制作方法。 该方法包括提供第一和第二管，并沿着接口区域将第一管的一段与第二管的一段并排布置。 管沿着界面区域的至少一部分被强制为非线性形状。 将粘合剂施加到界面区域的部分并固化。 在固化时，粘合剂将管彼此粘合，并且在没有外力的情况下弹性地保持非线性形状。 导电元件设置在至少一个管内。 在一些实施例中，非线性形状是S形，并且该方法包括将管段布置在具有限定S形结构的固定装置中。
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公开(公告)号：US07725198B2
公开(公告)日：2010-05-25
申请号：US11742454
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0582
摘要： Implantable lead assembly including a lead body, an elongated conductor, a coiled electrode, and a tether line. The lead body maintains the conductor. The electrode is coupled to the conductor, defining proximal and distal ends. The tether line defines a trailing segment and a leading segment terminating in a leading end. The tether line is coupled to the coiled electrode at a point proximal the distal end, and the leading end extends distal the distal end. With this configuration, a pulling force applied to the leading segment is transferred to the electrode at a point proximal the distal end as a pushing force, thereby minimizing an opportunity for overt stretching of the coiled electrode during implantation. The lead assembly can further include a needle connected to the tether line.
摘要翻译： 可植入引线组件，包括引线体，细长导体，线圈电极和系绳。 导体保持导体。 电极耦合到导体，限定近端和远端。 系绳线定义了一个尾部段和一个终端在前端的前导段。 系绳线在靠近远端的点处连接到线圈电极，并且前端延伸到远端。 利用这种构造，作用在前端的拉力作为推力在靠近远端的点转移到电极，从而最小化植入期间线圈电极的明显拉伸的机会。 导线组件还可以包括连接到系绳线的针。
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公开(公告)号：US20080269860A1
公开(公告)日：2008-10-30
申请号：US11742449
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： Implantable medical leads and methods of making. The method includes providing first and second tubes, and arranging a segment of the first tube side-by-side with a segment of the second tube along a region of interface. The tubes are forced to a non-linear shape along at least a portion of the region of interface. An adhesive is applied to the portion of the region of interface and cured. Upon curing, the adhesive bonds the tubes to one another and elastically maintains the non-linear shape in the absence of an external force. A conductive element is disposed within at least one of the tubes. In some embodiments, the non-linear shape is a sigmoid shape, and the method includes arranging the tube segments in a fixture having a structure defining the sigmoid shape.
摘要翻译： 植入式医疗线索和制作方法。 该方法包括提供第一和第二管，并沿着接口区域将第一管的一段与第二管的一段并排布置。 管沿着界面区域的至少一部分被强制为非线性形状。 将粘合剂施加到界面区域的部分并固化。 在固化时，粘合剂将管彼此粘合，并且在没有外力的情况下弹性地保持非线性形状。 导电元件设置在至少一个管内。 在一些实施例中，非线性形状是S形，并且该方法包括将管段布置在具有限定S形结构的固定装置中。
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4.发明申请IMPLANTABLE MEDICAL LEADS WITH FLEXIBILITY AND EXTENSIBILITY, AND HAVING A SUBSTANTIALLY TWO-DIMENSIONAL NATURE 审中-公开具有灵活性和可扩展性，并具有重大二维性质的可植入医疗领域公开(公告)号：US20080269858A1
公开(公告)日：2008-10-30
申请号：US11742413
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： Implantable medical leads that are flexible and extensible in a controllable manner with a substantially two-dimensional profile to fit between adjacent tissue layers and to facilitate subject body movements. In particular, implantable medical leads able to permit and withstand multiple degree of freedom of movement that are useful for use in the neck region of a subject body and other regions of any subject's body that may benefit from increased flexibility and extensibility. Features of medical leads are utilized to permit extensibility and are based upon the provision of shaped features that controllably permit lead extension under low load, but that maintain a desired shape under no load. The shaped lead portions provide extensibility to the lead as the shapes elastically deform under load.
摘要翻译： 可植入医疗引线，其可控制地具有柔性和可扩展性，具有基本上二维轮廓以适合相邻组织层之间并且便于受试者身体运动。 特别地，可植入医疗引线能够允许和承受可用于受试者身体的颈部区域和可能受益于增加的柔韧性和延展性的任何受试者身体的其他区域的多个运动自由度。 医疗引线的特征被用于允许可扩展性，并且基于提供可控制地允许在低负载下引线延伸但是在无负载下保持期望形状的成形特征。 当形状在负载下弹性变形时，成形的引线部分向引线提供延展性。
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5.发明申请IMPLANTABLE MEDICAL LEADS AND LEAD ASSEMBLIES WITH FLEXIBILITY, EXTENSIBILITY AND BRANCHED STRUCTURES 审中-公开具有灵活性，可扩展性和分支结构的可塑性医疗领导和铅组件公开(公告)号：US20080269857A1
公开(公告)日：2008-10-30
申请号：US11742412
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： Implantable medical leads that are flexible and extensible in a controllable manner to facilitate subject body movements and that are bundled to create a branched lead to permit lead body ends on one or both ends of the lead to be movable relative to one another so as to be positionable in different locations. Implantable medical leads advantageously include individual lead portions, sub-bundles, and bundles that are able to be selectively positioned and implanted within a subject body and that are useful, in particular, for use in the neck region of a subject body and other regions of any subject's body that may benefit from increased flexibility, extensibility and positionability.
摘要翻译： 可植入医疗引线，其可控制地以可控的方式灵活和可延伸，以便于受试者的身体运动并且被捆扎以产生分支导线，以允许引线的一端或两端的引线体端部相对于彼此可移动， 可定位于不同的地点。 可植入医疗引线有利地包括单独的引线部分，子束和束，其能够被选择性地定位并植入到受试者体内，并且特别是可用于主体和其他区域的颈部区域 任何受试者的身体可能受益于增加的灵活性，可扩展性和定位性。
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6.发明申请IMPLANTABLE MEDICAL LEADS WITH FLEXIBILITY AND EXTENSIBILITY TO FACILITATE BODY MOVEMENTS 审中-公开具有灵活性和可扩展性的植入式医疗导线，促进身体运动公开(公告)号：US20080269856A1
公开(公告)日：2008-10-30
申请号：US11742406
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： Implantable medical leads that are flexible and extensible in a controllable manner to facilitate subject body movements, able to permit and withstand multiple degree of freedom of movement that are useful for use in the neck region of a subject body and other regions of any subject's body that may benefit from increased flexibility and extensibility. Features of medical leads are utilized to permit extensibility and are based upon the provision of shaped features that controllably permit lead extension under low load, but that maintain a desired shape under no load. The shaped lead portions provide extensibility to the lead as the shapes elastically deform under load. A shaping element, such as an elongate element or a tube defines and holds the lead in the desired shape, which may comprise one or more series of sigmoid shapes as a pattern.
摘要翻译： 植入式医疗引线以可控的方式灵活和可扩展，以便于受试者的身体运动，能够允许和承受可用于主体和受试者身体的其他区域的颈部区域的多个运动自由度， 可能会受益于增加的灵活性和可扩展性。 医疗引线的特征被用于允许可扩展性，并且基于提供可控制地允许在低负载下引线延伸但是在无负载下保持期望形状的成形特征。 当形状在负载下弹性变形时，成形的引线部分向引线提供延展性。 诸如细长元件或管的成形元件将引线限定和保持为期望形状，其可以包括一个或多个S形作为图案。
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7.发明申请Implantable medical assemblies with improved flexibility, extensibility and positionability with branched structures 审中-公开植入式医疗组件具有改进的灵活性，可扩展性和具有分支结构的定位性公开(公告)号：US20080051861A1
公开(公告)日：2008-02-28
申请号：US11413437
申请日：2006-04-28
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0551
摘要： Implantable medical lead assemblies of a plurality of leads that are flexible and extensible in a controllable manner to facilitate subject body movements and that are bundled to create a branched lead assembly to permit lead ends on one or both ends of the lead assembly to be movable relative to one another so as to be positionable in different locations. In particular, implantable medical lead assemblies advantageously include individual lead portions, lead sub-bundles, and lead bundles that are able to be selectively positioned and implanted within a subject body and that are useful, in particular, for use in the neck region of a subject body and other regions of any subject's body that may benefit from increased flexibility, extensibility and positionability.
摘要翻译： 多个引线的可植入医疗引线组件，其以可控制的方式是柔性和可延伸的，以便于本体移动并且被捆扎以形成分支引线组件，以允许引线组件的一端或两端的引线端可移动相对 以便在不同的位置定位。 特别地，可植入医疗引线组件有利地包括单独的引线部分，引线子束和引线束，其能够被选择性地定位和植入在主体内，并且特别用于颈部区域 受试者身体和任何受试者身体的其他区域可能受益于增加的灵活性，可扩展性和定位性。
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8.发明申请Implantable medical leads and lead assemblies with improved flexibility and extensibility to facilitate body movements 审中-公开可植入的医用引线和引线组件，具有改进的灵活性和可扩展性，以促进身体运动公开(公告)号：US20080039917A1
公开(公告)日：2008-02-14
申请号：US11413316
申请日：2006-04-28
IPC分类号： A61N1/04
CPC分类号： A61N1/05 , A61N1/0551
摘要： Implantable medical leads that are flexible and extensible in a controllable manner to facilitate subject body movements. In particular, implantable medical leads advantageously are able to permit and withstand multiple degree of freedom that are useful for use in the neck region of a subject body and other regions of any subject's body that may benefit from increased flexibility and extensibility. Preferably, features of medical leads are utilized to permit extensibility and are based upon the provision of shaped features that controllably permit lead extension under low load, but that maintain a desired shape under no load. The shaped lead portions provide extensibility to the lead as the shapes elastically deform under load. Preferably, a shaping element, such as an elongate element or a tube defines and holds the lead in the desired shape, which most preferably comprises one or more series of sigmoid shapes as a pattern. Also, multiple leads can be utilized together as a medical lead assembly while having flexibility and extensibility after implantation and electrical connection within a subject's body.
摘要翻译： 植入式医疗引线，以可控的方式灵活和可扩展，便于受试者的身体运动。 特别地，可植入医疗引线有利地能够允许和承受可用于受试者身体的颈部区域和可能受益于增加的柔性和延展性的任何受试者身体的其它区域的多重自由度。 优选地，医疗引线的特征被用于允许可延展性，并且基于提供可控地允许在低负载下的引线延伸但是在无负载下保持期望形状的成形特征。 当形状在负载下弹性变形时，成形的引线部分向引线提供延展性。 优选地，诸如细长元件或管的成形元件限定并保持期望形状的引线，其最优选地包括一个或多个S形模型作为图案。 此外，多个引线可以一起用作医疗引线组件，同时在植入之后具有灵活性和可延展性并且在受试者的身体内进行电连接。
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公开(公告)号：US20080269861A1
公开(公告)日：2008-10-30
申请号：US11742454
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0582
摘要： Implantable lead assembly including a lead body, an elongated conductor, a coiled electrode, and a tether line. The lead body maintains the conductor. The electrode is coupled to the conductor, defining proximal and distal ends. The tether line defines a trailing segment and a leading segment terminating in a leading end. The tether line is coupled to the coiled electrode at a point proximal the distal end, and the leading end extends distal the distal end. With this configuration, a pulling force applied to the leading segment is transferred to the electrode at a point proximal the distal end as a pushing force, thereby minimizing an opportunity for overt stretching of the coiled electrode during implantation. The lead assembly can further include a needle connected to the tether line.
摘要翻译： 可植入引线组件，包括引线体，细长导体，线圈电极和系绳。 导体保持导体。 电极耦合到导体，限定近端和远端。 系绳线定义了一个尾部段和一个终端在前端的前导段。 系绳线在靠近远端的点处联接到线圈电极，并且前端延伸到远端。 利用这种构造，作用在前端的拉力作为推力在靠近远端的点转移到电极，从而最小化植入期间线圈电极的明显拉伸的机会。 导线组件还可以包括连接到系绳线的针。
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10.发明申请METHODS FOR CUSTOMIZING IMPLANTABLE MEDICAL LEADS AND LEAD ASSEMBLIES WITH IMPROVED FLEXIBILITY AND EXTENSIBILITY 审中-公开用于定制可塑性医疗领域和铅组件的方法具有改进的灵活性和可扩展性公开(公告)号：US20080269859A1
公开(公告)日：2008-10-30
申请号：US11742427
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/0558
摘要： Implantable medical leads that are customizable and that are flexible and extensible in a controllable manner to facilitate subject body movements. In particular, implantable medical leads include the ability to be customized by selective and controllable separation of lead bodies from one another, which leads are also able to permit and withstand multiple degree of freedom of movement that are useful for use in the neck region of a subject body and other regions of any subject's body that may benefit from increased flexibility and extensibility.
摘要翻译： 可植入的医用引线是可定制的，并且以可控的方式灵活和可扩展以便于受试者的身体运动。 特别地，可植入医疗引线包括通过铅体彼此的选择性和可控的分离来定制的能力，这些引导也能够允许和承受可用于颈部区域中的多个运动自由度 受试者身体和任何受试者身体的其他区域可能受益于增加的灵活性和可扩展性。
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