公开(公告)号：US20060148683A1

公开(公告)日：2006-07-06

申请号：US10492108

申请日：2002-10-16

申请人： Thomas McMurry ,  Robert Weisskoff

发明人： Thomas McMurry ,  Robert Weisskoff

IPC分类号： A61K38/12 ,  A61K38/10

CPC分类号： A61K49/0056 ,  A61K38/08 ,  A61K38/12 ,  A61K38/49 ,  A61K49/0039 ,  A61K49/0041 ,  A61K49/0043

摘要： Optical agents that contain a fibrin binding moiety covalently linked to an optical dye are described, as well as methods of treating intravascular lesions in a patient using such optical agents.

摘要翻译： 描述了包含与光学染料共价连接的纤维蛋白结合部分的光学剂，以及使用这种光学剂治疗患者的血管内病变的方法。

公开(公告)号：US20060210478A1

公开(公告)日：2006-09-21

申请号：US11346884

申请日：2006-02-03

申请人： Robert Weisskoff

发明人： Robert Weisskoff

IPC分类号： A61K49/00

CPC分类号： A61K49/103

摘要： Methods for assessing ischemic coronary artery disease are provided. The methods include administering a contrast agent that binds to a serum protein component to an animal and obtaining an MR image of the animal's myocardium during a period when the animal is experiencing hyperemia.

摘要翻译： 提供了评估缺血性冠状动脉疾病的方法。 所述方法包括在动物正在经历充血的时期期间施用结合动物的血清蛋白组分的造影剂并获得动物心肌的MR图像。

公开(公告)号：US20060116568A1

公开(公告)日：2006-06-01

申请号：US11122844

申请日：2005-05-05

申请人： Robert Stefancik ,  Randy Earnest ,  Robert Weisskoff

发明人： Robert Stefancik ,  Randy Earnest ,  Robert Weisskoff

IPC分类号： A61B5/05

CPC分类号： G01R33/563 ,  A61B5/055 ,  G06T5/008 ,  G06T5/50 ,  G06T7/38 ,  G06T2207/10088 ,  G06T2207/30048 ,  G06T2207/30061 ,  G06T2207/30101

摘要： A method is provided for improved visualization of vascular structures contained within magnetic resonance angiograms, particularly steady-state contrast-enhanced magnetic resonance angiograms. The disclosed methods include manipulating the relative enhancement levels of the arterial and venous blood pools images with respect to each other and to the surrounding anatomy. This manipulation is meant to optimize visualization of one or both of the individual blood pools without the necessity of completely obscuring or removing the supporting information given by presentation of the other blood pool and/or the surrounding anatomy.

公开(公告)号：US20060018834A1

公开(公告)日：2006-01-26

申请号：US11184271

申请日：2005-07-18

申请人： Robert Weisskoff ,  Stephen Knight ,  Wayne Carter

发明人： Robert Weisskoff ,  Stephen Knight ,  Wayne Carter

IPC分类号： A61K49/00

CPC分类号： A61B6/481 ,  A61B5/055 ,  A61B6/507 ,  A61B6/508 ,  A61B8/06 ,  A61B8/481 ,  A61K49/0008

摘要： The present invention relates to methods for contrast-enhanced imaging of sexual response. In particular, the present invention relates to methods of magnetic resonance imaging (MRI), computerized X-ray tomography (CT), ultrasound, and optical imaging using contrast agents to measure blood flow during sexual response, especially female sexual response. The invention relates to methods of analyzing normal sexual function and sexual dysfunction and provides a means for evaluating and screening potential therapeutic compounds for enhancing sexual function or treating sexual dysfunction.