公开(公告)号：US4354904A

公开(公告)日：1982-10-19

申请号：US234516

申请日：1981-02-13

申请人： Thomas P. Malloy ,  Mark A. Halter ,  David W. House

发明人： Thomas P. Malloy ,  Mark A. Halter ,  David W. House

IPC分类号： C25B3/02

CPC分类号： C25B3/02

摘要： Aromatic aldehydes may be prepared by subjecting a methyl-substituted aromatic compound to an electrical energy which includes a direct electrical current utilizing a basic medium to form an acetal, following which the acetal may be converted to the desired aldehyde by subjecting said acetal to acid hydrolysis.

摘要翻译： 芳族醛可以通过使甲基取代的芳族化合物经受包括使用碱性介质的直接电流以形成缩醛的电能来制备，随后通过使所述缩醛进行酸水解将缩醛转化为所需的醛 。

公开(公告)号：US4459186A

公开(公告)日：1984-07-10

申请号：US412403

申请日：1982-08-27

申请人： Thomas P. Malloy ,  Mark A. Halter ,  David W. House

发明人： Thomas P. Malloy ,  Mark A. Halter ,  David W. House

IPC分类号： C25B3/02

CPC分类号： C25B3/02

摘要： Aromatic ketones may be prepared by subjecting an alkyl aromatic compound containing more than one carbon atom in the alkyl substituent to an electrical energy which includes a direct electrical current in the presence of a nucleophile such as an organometallic oxide, a solvent and a reaction initiator such as an alkali metal hydroxide and a quaternary ammonium hydroxide to produce a ketal, following which the ketal may be converted to the desired ketone by hydrolysis.

摘要翻译： 芳族酮可以通过使烷基取代基中含有多于一个碳原子的烷基芳族化合物在亲核试剂如有机金属氧化物，溶剂和反应引发剂等存在下包含直接电流来进行制备 作为碱金属氢氧化物和季铵氢氧化物以产生缩酮，随后可以通过水解将缩酮转化为所需的酮。

公开(公告)号：US4212711A

公开(公告)日：1980-07-15

申请号：US52646

申请日：1979-06-27

申请人： Mark A. Halter ,  Thomas P. Malloy

发明人： Mark A. Halter ,  Thomas P. Malloy

IPC分类号： C25B3/02

CPC分类号： C25B3/02

摘要： Alkyl aromatic compounds may be subjected to an electrochemical oxidation in an appropriate electrochemical cell utilizing a semi-emulsion solution comprising said alkyl aromatic compound in a dilute mineral acid solution containing a salt of a transition metal. The reaction is preferably effected at ambient temperature and atmospheric pressure utilizing an electrical energy which includes a voltage in the range of from about 2 to about 20 volts or a current density in the range of from about 0 to about 1000 miliamps per square centimeter.

摘要翻译： 烷基芳族化合物可以在合适的电化学电池中使用包含所述烷基芳族化合物的半乳液溶液在含有过渡金属盐的稀无机酸溶液中进行电化学氧化。 反应优选在环境温度和大气压下使用包括约2至约20伏范围内的电压或约0至约1000毫升每平方厘米范围内的电流密度的电能来实现。

公开(公告)号：US4212710A

公开(公告)日：1980-07-15

申请号：US52645

申请日：1979-06-27

申请人： Mark A. Halter ,  Thomas P. Malloy

发明人： Mark A. Halter ,  Thomas P. Malloy

IPC分类号： C25B3/02

CPC分类号： C25B3/02

摘要： Alkyl aromatic compounds may be subjected to electrochemical oxidation in an appropriate electrochemical cell utilizing an emulsion solution comprising said alkyl aromatic compound in an aqueous acidic medium which contains a salt of a transition metal. The reaction is effected at ambient temperature and atmospheric pressure utilizing an electrical energy which includes a voltage in the range of from 2 to about 30 volts or a current density in the range of from about 20 to about 1000 milliamps per square centimeter.

摘要翻译： 烷基芳族化合物可以在合适的电化学电池中使用包含所述烷基芳族化合物的乳液在含有过渡金属盐的酸性介质的酸性介质中进行电化学氧化。 反应在环境温度和大气压下使用包括2至约30伏范围内的电压或约20至约1000毫安/平方厘米范围内的电流密度的电能进行。

公开(公告)号：US5354875A

公开(公告)日：1994-10-11

申请号：US172314

申请日：1993-12-23

申请人： Laszlo T. Nemeth ,  Thomas P. Malloy ,  Richard R. Jones

发明人： Laszlo T. Nemeth ,  Thomas P. Malloy ,  Richard R. Jones

IPC分类号： B01J29/89 ,  C07D301/12 ,  C07D301/14 ,  C07D301/19 ,  C07D303/04

CPC分类号： B01J29/89 ,  C07D301/12

摘要： The oxidation of olefinic compounds generally using hydroperoxides, especially aqueous solutions of hydrogen peroxide, can be effected in high yield and with good selectivity in the presence of a titania-supported titanosilicate catalyst. Dilute aqueous hydrogen peroxide solutions may be used with good results. The resulting epoxidation, even when carried out at modest temperatures and with dilute aqueous hydrogen peroxide solutions, afford superior results in epoxidation relative to TS-1.

摘要翻译： 通常使用氢过氧化物，特别是过氧化氢水溶液的烯属化合物的氧化可以以高产率和在二氧化钛负载的钛硅酸盐催化剂的存在下以良好的选择性进行。 可以使用稀释的过氧化氢水溶液，结果良好。 所得到的环氧化，即使在适度的温度下进行并且用稀的过氧化氢水溶液进行，在相对于TS-1的环氧化中也提供了优异的结果。

公开(公告)号：US5124492A

公开(公告)日：1992-06-23

申请号：US653921

申请日：1991-02-12

申请人： Chwu-Ching Jan ,  Thomas P. Malloy

发明人： Chwu-Ching Jan ,  Thomas P. Malloy

IPC分类号： C07C29/88

CPC分类号： C07C29/88

摘要： This invention relates to a process for removing peroxide impurities contained in a tertiary butyl alcohol feedstock. The process involves contacting the feedstock with an iron (II) compound such as iron (II) chloride, under an inert atmosphere at elevated pressures and temperatures for a time sufficient to reduce the peroxides to alcohols and oxidize the iron (II) to iron (III). The iron (II) compound may be added in a homogeneous phase or it may be deposited on a support. When the iron (II) is added as a homogeneous phase, it is separated from the product by contacting the mixture with a cation exchange column. Finally, when a supported iron (II) compound is used, the process may be run in a batch or continuous mode.

摘要翻译： 本发明涉及一种除去叔丁醇原料中所含的过氧化物杂质的方法。 该方法包括在惰性气氛下在升高的压力和温度下将原料与铁（II）化合物如氯化铁（II）接触一段时间，足以将过氧化物还原成醇并将铁（II）氧化成铁（ III）。 铁（II）化合物可以以均匀相加入，或者可以沉积在载体上。 当铁（II）以均相加入时，通过使该混合物与阳离子交换柱接触将其与产物分离。 最后，当使用负载的铁（II）化合物时，该过程可以以分批或连续模式运行。

公开(公告)号：US5350879A

公开(公告)日：1994-09-27

申请号：US153409

申请日：1993-11-17

申请人： Dusan J. Engel ,  Thomas P. Malloy ,  Peter K. Nickl

发明人： Dusan J. Engel ,  Thomas P. Malloy ,  Peter K. Nickl

IPC分类号： C07C27/02 ,  C07C29/128 ,  C07C67/03 ,  C07C67/02 ,  C07C27/10

CPC分类号： C07C29/1285 ,  C07C67/03

摘要： Base-catalyzed transesterification may be effected in the presence of certain metal oxide solid solutions and layered double hydroxides as the basic catalyst. Use of the latter materials as the base catalyst readily permits one to conduct transesterification in a continuous manner. Such a continuous process is applicable to esters generally and is not limited to any particular structural types of esters or alcohols. Transesterification of detergent range alkyl acetates by this method leads to the formation of the corresponding detergent range alcohols in excellent yield and with quite high selectivity.

摘要翻译： 碱催化的酯交换可以在某些金属氧化物固溶体和层状双氢氧化物作为碱性催化剂的存在下进行。 使用后一种材料作为碱催化剂容易使其以连续的方式进行酯交换。 这种连续方法通常适用于酯，并不限于任何特定结构类型的酯或醇。 通过该方法的洗涤剂范围的烷基乙酸酯的酯交换导致相当的洗涤剂范围的醇的形成，其产率和产率都非常高，并具有相当高的选择性。

公开(公告)号：US4581336A

公开(公告)日：1986-04-08

申请号：US539195

申请日：1983-10-05

申请人： Thomas P. Malloy ,  Louis J. DeFilippi

发明人： Thomas P. Malloy ,  Louis J. DeFilippi

IPC分类号： C12N11/14 ,  C12Q1/00 ,  C12M1/40 ,  C12N11/06 ,  C12N11/08

CPC分类号： C12Q1/003 ,  C12N11/14

摘要： Surface-modified electrodes which may be used in electrochemical cells for production of electrical energy comprise an enzyme immobilized on a support. The support consists of at least a monolayer coating of a carbonaceous pyropolymer possessing recurring units containing at least carbon and hydrogen atoms composited on a high surface area refractory inorganic oxide such that the carbonaceous pyropolymer monolayer coating replicates the surface area and macropore volume of the inorganic oxide. The coated support is then treated by impregnation with a water-soluble polyamine followed by contact with a solution of a molar excess of a bifunctional monomeric material to form a copolymer which provides pendant bonding sites. The copolymer is entrapped and adsorbed in the pores of the support material to provide a permanent attachment thereto. The treated support is then contacted with an excess of an enzyme to effect the conjugate attachment of the enzyme to the treated support. The immobilized enzyme will act as a working electrode in the presence of a predetermined substrate such as glucose to provide electrical energy.

摘要翻译： 可用于生产电能的电化学电池中的表面改性电极包括固定在载体上的酶。 载体由至少含有碳质焦磷酸聚合物的单层涂层组成，其具有在高表面积耐火无机氧化物上复合的至少含有碳原子和氢原子的重复单元，使得碳质高分子单层涂层复制无机氧化物的表面积和大孔体积 。 然后将涂覆的载体用水溶性多胺浸渍处理，然后与摩尔过量的双官能单体材料的溶液接触以形成提供侧链键合位点的共聚物。 共聚物被截留并吸附在支撑材料的孔中以提供永久性附着。 然后将经处理的载体与过量的酶接触以实现酶与经处理的载体的缀合物连接。 固定化酶将在诸如葡萄糖的预定底物存在下用作工作电极以提供电能。

公开(公告)号：US4499300A

公开(公告)日：1985-02-12

申请号：US566007

申请日：1983-12-27

申请人： Thomas P. Malloy ,  Dusan J. Engel

发明人： Thomas P. Malloy ,  Dusan J. Engel

IPC分类号： C07C45/36 ,  C07C51/00 ,  C07C51/363 ,  C07C51/377 ,  C07C63/64

CPC分类号： C07C51/363 ,  C07C45/36 ,  C07C51/00 ,  C07C51/377

摘要： A multi-step preparation of 4-vinylbenzeneacetic acid from the readily available 1,4-diethylbenzene is described. The method uses cobalt (II) catalyzed oxidation of 1,4-diethylbenzene to 4-ethylacetophenone followed by oxidative rearrangement of the latter to 4-ethylbenzeneacetic acid, selective photochlorination to produce 4-(1'-chloroethyl)benzeneacetic acid, and finally base-catalyzed dehydrochlorination of the latter to afford the title compound.

摘要翻译： 描述了从容易获得的1,4-二乙基苯中多步制备4-乙烯基苯乙酸。 该方法使用1,4-二乙基苯（II）催化氧化成4-乙基苯乙酮，随后将其氧化重排为4-乙基苯乙酸，进行选择性光氯化，得到4-（1'-氯乙基）苯乙酸，最后碱 将其催化脱氯化氢，得到标题化合物。

公开(公告)号：US4323715A

公开(公告)日：1982-04-06

申请号：US208954

申请日：1980-11-20

申请人： Dusan J. Engel ,  Thomas P. Malloy

发明人： Dusan J. Engel ,  Thomas P. Malloy

IPC分类号： C07C37/14 ,  C07C37/11 ,  C07C39/08

CPC分类号： C07C37/14

摘要： Mono-tertiary butylhydroquinone may be prepared in a continuous method of operation by reacting hydroquinone with isobutylene in the presence of an acidic alumina catalyst. The alkylation is effected in a reaction medium which comprises an ether, and particularly a polyether such as the dimethyl ether of triethylene glycol.

摘要翻译： 单叔丁基氢醌可以通过在酸性氧化铝催化剂存在下使氢醌与异丁烯反应而以连续的操作方法制备。 烷基化反应在包括醚，特别是聚醚如三甘醇的二甲醚的反应介质中进行。