Steerable guide wire with torsionally stable tip
    1.
    发明授权
    Steerable guide wire with torsionally stable tip 有权
    导向扭矩稳定的导丝

    公开(公告)号:US08353850B2

    公开(公告)日:2013-01-15

    申请号:US12484910

    申请日:2009-06-15

    IPC分类号: A61B5/00

    摘要: A steerable guide wire includes a core wire having a proximal end and a distal end. A braided filament is affixed to the distal end of the core wire. An outer coil surrounds at least a portion of the core wire and the braided filament. A proximal end of the braided filament is secured to a distal end of the coil. By locating the braided filament in the distal tip portion of the guide wire, a guide wire is provided that is highly flexible, has a high degree of tensile integrity, and is highly steerable, even in tortuous vasculature. Filter and balloon catheters having braided filaments at the distal end are also described.

    摘要翻译: 可导向的导丝线包括具有近端和远端的芯线。 编织丝固定在芯线的远端。 外部线圈围绕芯线和编织细丝的至少一部分。 编织丝的近端固定到线圈的远端。 通过将编织丝定位在导丝的远侧末端部分,提供了一种导丝,其具有高柔性,具有高度的拉伸完整性,并且即使在曲折的脉管系统中也是高度可操纵的。 还描述了在远端具有编织细丝的过滤器和球囊导管。

    Embolic protection device and methods of use
    5.
    发明授权
    Embolic protection device and methods of use 有权
    栓塞保护装置及使用方法

    公开(公告)号:US08221348B2

    公开(公告)日:2012-07-17

    申请号:US11177473

    申请日:2005-07-07

    IPC分类号: A61M29/00

    摘要: An evacuation sheath assembly and method of reducing or removing a blockage within a vessel without permitting embolization of particulate matter is provided. The evacuation sheath assembly includes a first elongate tubular member, having proximal and distal ends and a main lumen configured to be placed in fluid communication with a blood vessel. An expandable member is provided on a distal portion of the tubular member and is configured to form a seal with the blood vessel. The evacuation assembly further includes a second elongate tubular member having proximal and distal ends and an inflation lumen configured to be placed in fluid communication with the expandable member and a gas inflator. The gas inflator includes a high pressure gas source and a mechanism for regulating the pressure of the gas delivered by the gas inflator. The gas inflator is configured to be placed in fluid communication with the proximal end of the inflation lumen in order to provide a regulated pressure gas source for inflating the expandable member. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. The expandable member is inflated to provide form a seal between the blood vessel and the guide catheter and a vacuum is applied to the main lumen of the first elongate tubular member to cause retrograde blood flow and carry fluid into the main lumen of the evacuation sheath assembly.

    摘要翻译: 提供疏散护套组件以及在不允许颗粒物质栓塞的情况下减少或去除容器内的堵塞的方法。 抽真空组件包括第一细长管状构件,其具有近端和远端以及构造成与血管流体连通的主腔。 可膨胀构件设置在管状构件的远侧部分上并构造成与血管形成密封。 排气组件还包括具有近端和远端的第二细长管状构件和构造成与膨胀构件和气体充气器流体连通的膨胀腔。 气体充气机包括高压气体源和用于调节由气体充气机输送的气体的压力的机构。 气体充气器被配置成与膨胀腔的近端流体连通,以便提供用于使可膨胀构件膨胀的调节压力气体源。 使用排气鞘组件治疗血管的方法包括通过引导导管将排空鞘组件推进到血管中。 可膨胀构件被膨胀以在血管和引导导管之间形成密封,并且将真空施加到第一细长管状构件的主腔,以引起逆行血流并将流体携带到排泄鞘组件的主腔内 。

    PFO closure devices and related methods of use
    6.
    发明授权
    PFO closure devices and related methods of use 有权
    PFO封闭装置及相关使用方法

    公开(公告)号:US07976564B2

    公开(公告)日:2011-07-12

    申请号:US10138565

    申请日:2002-05-06

    IPC分类号: A61B17/08

    摘要: Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

    摘要翻译: 提供用于密封由心脏中的卵圆孔卵孔(PFO轨迹)形成的通道的装置和方法。 一种方法包括向PFO轨道提供研磨装置并研磨PFO轨道内的组织。 形成PFO轨道的磨损组织然后在压力下保持在一起,或者通过降低右心房压力或通过向隔膜施加抽吸使其与隔膜隔层相对。 经过足够的时间后,释放压力,磨损的组织愈合,在PFO轨迹上形成牢固的密封。 另外,提供了可以放置到PFO轨道中以将粘合剂施加到PFO轨道的壁上的几个装置。 设备可能会留在PFO轨道中,也可能不会留在PFO轨道中。 如果设备不在PFO轨道内,PFO轨道的墙壁被粘合剂覆盖,彼此并置并粘合在一起。 如果设备留在PFO轨道内,则设备将从扩展配置平坦化到平坦的配置,并且随着设备平坦化,PFO轨道的粘附在设备外表面上的墙壁会相互拉紧。 该装置还可以包括用于将装置保持在扁平结构中的内部结构。

    PFO CLOSURE DEVICES AND RELATED METHODS OF USE
    7.
    发明申请
    PFO CLOSURE DEVICES AND RELATED METHODS OF USE 审中-公开
    PFO封闭装置及相关使用方法

    公开(公告)号:US20100234881A1

    公开(公告)日:2010-09-16

    申请号:US12725886

    申请日:2010-03-17

    IPC分类号: A61B17/03

    摘要: Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

    摘要翻译: 提供用于密封由心脏中的卵圆孔卵孔(PFO轨迹)形成的通道的装置和方法。 一种方法包括向PFO轨道提供研磨装置并研磨PFO轨道内的组织。 形成PFO轨道的磨损组织然后在压力下保持在一起,或者通过降低右心房压力或通过向隔膜施加抽吸使其与隔膜隔层相对。 经过足够的时间后,释放压力,磨损的组织愈合,在PFO轨迹上形成牢固的密封。 另外,提供了可以放置到PFO轨道中以将粘合剂施加到PFO轨道的壁上的几个装置。 设备可能会留在PFO轨道中,也可能不会留在PFO轨道中。 如果设备不在PFO轨道内,PFO轨道的墙壁被粘合剂覆盖,彼此并置并粘合在一起。 如果设备留在PFO轨道内,则设备将从扩展配置平坦化到平坦的配置,并且随着设备平坦化,PFO轨道的粘附在设备外表面上的墙壁会相互拉紧。 该装置还可以包括用于将装置保持在扁平结构中的内部结构。

    GUIDE WIRE CONTROL CATHETER FOR CROSSING OCCLUSIONS AND RELATED METHODS OF USE
    8.
    发明申请
    GUIDE WIRE CONTROL CATHETER FOR CROSSING OCCLUSIONS AND RELATED METHODS OF USE 审中-公开
    导线控制导管及相关使用方法

    公开(公告)号:US20090005755A1

    公开(公告)日:2009-01-01

    申请号:US12207391

    申请日:2008-09-09

    IPC分类号: A61M25/09 A61M25/10

    摘要: A wire control catheter for aligning and guiding a guide wire through a lesion in a vessel is provided. The wire control catheter includes a shaft having a guide wire lumen and a control wire lumen. A control wire passes through the control wire lumen and is used in combination with an articulation structure to deflect or curve a distal tip portion of the catheter. The distal catheter shaft may include a centering device for centering the catheter within the vessel. The distal catheter shaft may also include a pre-dilation balloon for dilating the lesion prior to performing angioplasty or other treatment on the lesion. A method of treatment of a blood vessel includes inserting a guide wire into the blood vessel and advancing a control wire over the guide wire until the distal tip of the catheter is near the occlusion in the blood vessel. The tip of the catheter then is deflected via a control wire and an articulation structure. The guide wire is then advanced across the occlusion. The control wire also may be advanced across the occlusion simultaneously with the guide wire or subsequent to the guide wire crossing. Prior to crossing the occlusion, the wire control catheter may be centered using a centering device. Subsequent to crossing the occlusion, the occlusion may be pre-dilated with a pre-dilation balloon of the wire control catheter.

    摘要翻译: 提供了用于将引导线对准和引导通过血管中的病变的线控导管。 线控制导管包括具有导丝管腔和控制线腔的轴。 控制线穿过控制线腔,并且与关节运动结构组合使用以偏转或弯曲导管的远侧末端部分。 远侧导管轴可以包括用于将导管定心在容器内的定心装置。 远侧导管轴还可以包括用于在对病变进行血管成形术或其它治疗之前扩张病变的预扩张球囊。 一种治疗血管的方法包括将导丝插入血管并将控制线推进导丝,直到导管的远端顶端靠近血管内的闭塞。 然后,导管的尖端经由控制线和铰接结构偏转。 然后,导丝穿过遮挡物前进。 控制线也可以与引导线同时前进,或者在引导线交叉之后跨过遮挡。 在穿过闭塞之前,电线控制导管可以使用定心装置居中。 在穿过闭塞之后,闭塞可以用导线控制导管的预扩张气球预扩张。

    EMBOLI PROTECTION DEVICES AND RELATED METHODS OF USE
    9.
    发明申请
    EMBOLI PROTECTION DEVICES AND RELATED METHODS OF USE 审中-公开
    EMBOLI保护装置及相关使用方法

    公开(公告)号:US20080243171A1

    公开(公告)日:2008-10-02

    申请号:US12123374

    申请日:2008-05-19

    IPC分类号: A61M29/00

    摘要: An embolic protection system for treating a lesion in a blood vessel is provided. The embolic protection system includes a guide catheter, an evacuation sheath, a guidewire, and an infusion catheter. The guide catheter has a guidewire lumen. The evacuation sheath has an evacuation lumen and a sealing surface and is configured to move within the lumen of the guide catheter. The guidewire is configured to move within the lumen of the guide catheter and the evacuation lumen. The infusion catheter has an infusion lumen, at least one infusion port, and a guidewire lumen configured to accept the guidewire, the infusion catheter guidewire lumen being shorter than the guide catheter guidewire lumen. Furthermore, the infusion catheter is configured to move within the lumen of the guide catheter and the evacuation lumen over the guidewire. The system may further comprise a dilation catheter having a dilation balloon and a guidewire lumen.

    摘要翻译: 提供一种治疗血管病变的栓塞保护系统。 栓塞保护系统包括引导导管,抽真空鞘,导丝和输注导管。 引导导管具有导丝管腔。 抽真空鞘具有抽空腔和密封表面,并且构造成在导管的内腔内移动。 引导线被构造成在引导导管的内腔和排泄腔内移动。 输注导管具有输注腔,至少一个输注端口和构造成接纳导丝的导丝管腔,输液导管导丝管腔比引导导管导丝管腔更短。 此外,输注导管构造成在引导导管的内腔和引导线上的排空腔中移动。 该系统还可以包括具有扩张气囊和导丝管腔的扩张导管。

    PFO closure devices and related methods of use
    10.
    发明授权
    PFO closure devices and related methods of use 有权
    PFO封闭装置及相关使用方法

    公开(公告)号:US07691128B2

    公开(公告)日:2010-04-06

    申请号:US11249317

    申请日:2005-10-14

    IPC分类号: A61B17/08 A61D1/00

    摘要: Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

    摘要翻译: 提供用于密封由心脏中的卵圆孔卵孔(PFO轨迹)形成的通道的装置和方法。 一种方法包括向PFO轨道提供研磨装置并研磨PFO轨道内的组织。 形成PFO轨道的磨损组织然后在压力下保持在一起,或者通过降低右心房压力或通过向隔膜施加抽吸使其与隔膜隔层相对。 经过足够的时间后,释放压力,磨损的组织愈合,在PFO轨迹上形成牢固的密封。 另外,提供了可以放置到PFO轨道中以将粘合剂施加到PFO轨道的壁上的几个装置。 设备可能会留在PFO轨道中,也可能不会留在PFO轨道中。 如果设备不在PFO轨道内,PFO轨道的墙壁被粘合剂覆盖,彼此并置并粘合在一起。 如果设备留在PFO轨道内,则设备将从扩展配置平坦化到平坦的配置,并且随着设备平坦化,PFO轨道的粘附在设备外表面上的墙壁会相互拉紧。 该装置还可以包括用于将装置保持在扁平结构中的内部结构。