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公开(公告)号:US5847008A
公开(公告)日:1998-12-08
申请号:US797649
申请日:1997-01-31
申请人: Thomas W. Doebber , Joel P. Berger , Gregory D. Berger , Mark D. Leibowitz , David E. Moller , John T. Olson , Arthur A. Patchett , Richard B. Toupence
发明人: Thomas W. Doebber , Joel P. Berger , Gregory D. Berger , Mark D. Leibowitz , David E. Moller , John T. Olson , Arthur A. Patchett , Richard B. Toupence
IPC分类号: A61K31/192 , A61K31/216 , A61K31/235 , A61K31/277 , A61K45/06 , C07D209/08 , C07D217/06 , C07D271/12 , C07D307/79 , C07D307/82 , C07D307/83 , C07D307/91 , A61K31/105 , A61K31/10
CPC分类号: C07D307/79 , A61K31/192 , A61K31/216 , A61K31/235 , A61K31/277 , A61K45/06 , C07D209/08 , C07D217/06 , C07D271/12 , C07D307/82 , C07D307/83 , C07D307/91 , Y10S514/866 , Y10S514/909 , Y10S514/91
摘要: The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.
摘要翻译: 本发明涉及可用作抗肥胖和抗糖尿病化合物的乙酰苯酚。 还公开了用于治疗糖尿病和肥胖以及用于降低或调节甘油三酯水平和胆固醇水平或提高高密度脂蛋白水平或用于增加肠运动性或用于治疗动脉粥样硬化的组合物和方法。
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公开(公告)号:US06020382A
公开(公告)日:2000-02-01
申请号:US117654
申请日:1999-01-04
申请人: Thomas W. Doebber , Joel P. Berger , Gregory D. Berger , Mark D. Leibowitz , David E. Moller , John T. Olson , Arthur A. Patchett , Richard B. Toupence
发明人: Thomas W. Doebber , Joel P. Berger , Gregory D. Berger , Mark D. Leibowitz , David E. Moller , John T. Olson , Arthur A. Patchett , Richard B. Toupence
IPC分类号: A61K31/222 , A61K31/10 , A61K31/095 , A61K31/11 , A61K31/75
CPC分类号: A61K31/222
摘要: The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.
摘要翻译: PCT No.PCT / US97 / 01875 Sec。 371日期1999年1月4日 102(e)日期1999年1月4日PCT提交1997年1月31日PCT公布。 第WO97 / 27847号公报 日期1997年8月7日本发明涉及可用作抗肥胖和抗糖尿病化合物的乙酰苯酚。 还公开了用于治疗糖尿病和肥胖以及用于降低或调节甘油三酯水平和胆固醇水平或提高高密度脂蛋白水平或用于增加肠运动性或用于治疗动脉粥样硬化的组合物和方法。
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公开(公告)号:US06090836A
公开(公告)日:2000-07-18
申请号:US791211
申请日:1997-01-31
申请人: Alan D. Adams , Joel P. Berger , Gregory D. Berger , Kenneth J. Fitch , Donald W. Graham , Anthony B. Jones , Derek von Langen , Mark D. Leibowitz , David E. Moller , Arthur A. Patchett , Conrad Santini , Soumya P. Sahoo , Richard L. Tolman , Richard B. Toupence , Thomas F. Walsh
发明人: Alan D. Adams , Joel P. Berger , Gregory D. Berger , Kenneth J. Fitch , Donald W. Graham , Anthony B. Jones , Derek von Langen , Mark D. Leibowitz , David E. Moller , Arthur A. Patchett , Conrad Santini , Soumya P. Sahoo , Richard L. Tolman , Richard B. Toupence , Thomas F. Walsh
IPC分类号: A61K31/192 , A61K31/216 , A61K31/235 , A61K45/06 , C07D209/08 , C07D231/56 , C07D239/74 , C07D249/18 , C07D261/20 , C07D263/56 , C07D263/57 , C07D271/08 , C07D275/04 , C07D307/79 , C07D307/82 , C07D307/91 , C07D311/16 , A61K31/42 , A61K31/41 , C07D413/12
CPC分类号: C07D311/16 , A61K31/192 , A61K31/216 , A61K31/235 , A61K45/06 , C07D209/08 , C07D231/56 , C07D239/74 , C07D249/18 , C07D261/20 , C07D263/57 , C07D271/08 , C07D275/04 , C07D307/79 , C07D307/82 , C07D307/91
摘要: The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.
摘要翻译: 本发明涉及可用作抗肥胖和抗糖尿病化合物的乙酰苯酚。 还公开了用于治疗糖尿病和肥胖以及用于降低或调节甘油三酯水平和胆固醇水平或提高高密度脂蛋白水平或用于增加肠运动性或用于治疗动脉粥样硬化的组合物和方法。
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公开(公告)号:US5859051A
公开(公告)日:1999-01-12
申请号:US791213
申请日:1997-01-31
申请人: Alan D. Adams , Gregory D. Berger , Jeffrey P. Bergman , Joel P. Berger , Wei Han , Mark D. Leibowitz , David E. Moller , Conrad Santini , Soumya P. Sahoo , Richard L. Tolman , Jonthan R. Young
发明人: Alan D. Adams , Gregory D. Berger , Jeffrey P. Bergman , Joel P. Berger , Wei Han , Mark D. Leibowitz , David E. Moller , Conrad Santini , Soumya P. Sahoo , Richard L. Tolman , Jonthan R. Young
IPC分类号: C07D209/08 , C07D217/06 , C07D271/12 , C07D307/79 , C07D307/82 , C07D307/83 , C07D307/91 , C07D311/16 , C07D307/78 , A61K31/365 , A61K31/37
CPC分类号: C07D307/79 , C07D209/08 , C07D217/06 , C07D271/12 , C07D307/82 , C07D307/83 , C07D307/91 , C07D311/16
摘要: The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.
摘要翻译: 本发明涉及可用作抗肥胖和抗糖尿病化合物的乙酰苯酚。 还公开了用于治疗糖尿病和肥胖以及用于降低或调节甘油三酯水平和胆固醇水平或提高高密度脂蛋白水平或用于增加肠运动性或用于治疗动脉粥样硬化的组合物和方法。
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