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公开(公告)号:US06815078B2
公开(公告)日:2004-11-09
申请号:US10091644
申请日:2002-03-06
IPC分类号: B32B904
CPC分类号: C07K1/042 , C07B2200/11 , C07K1/047 , C40B40/00 , Y10S435/96 , Y10S436/809 , Y10T428/31768
摘要: A gelatin-based substrate for fabricating protein arrays, the substrate comprising: gelatin having at least one surface; a polymer scaffold affixed to the gelatin surface; wherein the polymer in the scaffold is rich in reactive units capable of immobilizing proteins.
摘要翻译: 一种用于制造蛋白质阵列的基于明胶的底物,所述底物包括:具有至少一个表面的明胶;固定到所述明胶表面的聚合物支架;其中所述支架中的聚合物富含能够固定蛋白质的反应单元。
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公开(公告)号:US06797393B2
公开(公告)日:2004-09-28
申请号:US10020747
申请日:2001-11-30
IPC分类号: B32B902
CPC分类号: B82Y30/00 , B01J2219/00274 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/0063 , B01J2219/00637 , B01J2219/00659 , B01J2219/00677 , B01J2219/00725 , C40B40/10 , G01N33/54353 , Y10T428/31504 , Y10T428/31768
摘要: A gelatin-based substrate for fabricating protein arrays, the substrate containing: gelatin and a trifunctional compound A—L—B; wherein A is a functional group capable of interacting with the gelatin; L is a linking group capable of interacting with A and with B; and B is a functional group capable of interacting with a protein capture agent. A may be the same or different from B.
摘要翻译: 用于制造蛋白质阵列的明胶基底物,所述基质含有:明胶和三官能化合物A-L-B; 其中A是能够与明胶相互作用的官能团; L是能够与A和B相互作用的连接基团; 并且B是能够与蛋白质捕获剂相互作用的官能团。 A可能与B相同或不同。
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公开(公告)号:US20080241266A1
公开(公告)日:2008-10-02
申请号:US11930759
申请日:2007-10-31
CPC分类号: A61K9/146 , A61K9/5146 , A61K49/0032 , A61K49/0043 , A61K49/0076 , A61K49/0093 , B01J13/04 , C03C12/00 , C03C17/32 , Y10T428/2991 , Y10T428/2993 , Y10T428/2998
摘要: There are disclosed colloids containing polymer-modified core-shell particle carrier. The described colloids containing core-shell nanoparticulate carrier particles wherein the shell contains a polymer having amine functionalities. The described carrier particles are stable under physiological conditions. The carriers can be bioconjugated with biological, pharmaceutical or diagnostic components.
摘要翻译: 公开了含有聚合物改性的核 - 壳粒子载体的胶体。 所述胶体含有核 - 壳纳米颗粒载体颗粒,其中壳包含具有胺官能团的聚合物。 所描述的载体颗粒在生理条件下是稳定的。 载体可以与生物,药物或诊断成分生物共轭。
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公开(公告)号:US06364456B1
公开(公告)日:2002-04-02
申请号:US09470809
申请日:1999-12-22
申请人: Zhihao Yang , Ravi Sharma , Thomas L. Penner
发明人: Zhihao Yang , Ravi Sharma , Thomas L. Penner
IPC分类号: B41J241
CPC分类号: B82Y30/00 , B41J2/1433 , B41J2/16552
摘要: A nozzle plate for an ink jet printhead, the nozzle plate having the following layers in the order recited: a) a first monomolecular layer of an organic material having first and second functional groups, the first functional group of the first monomolecular layer being bound to the surface of the nozzle plate, and the second functional group of the first monomolecular layer being bound to a second monomolecular layer, and b) the second monomolecular layer of an organic material having first and second functional groups, the first functional group of the second monomolecular layer being bound to the second functional group of the first monomolecular layer, and the second functional group of the second monomolecular layer is an anti-wetting group.
摘要翻译: 一种用于喷墨打印头的喷嘴板,喷嘴板具有以下顺序的层:a)具有第一和第二官能团的有机材料的第一单分子层,第一单分子层的第一官能团与 喷嘴板的表面和第一单分子层的第二官能团与第二单分子层结合,以及b)具有第一和第二官能团的有机材料的第二单分子层,第二官能团的第二官能团 单分子层与第一单分子层的第二官能团结合,第二单分子层的第二官能团为抗潮湿基团。
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公开(公告)号:US06345881B1
公开(公告)日:2002-02-12
申请号:US09408193
申请日:1999-09-29
申请人: Zhihao Yang , Yung-Rai Lee , Thomas L. Penner , Ravi Sharma
发明人: Zhihao Yang , Yung-Rai Lee , Thomas L. Penner , Ravi Sharma
IPC分类号: B41J2135
CPC分类号: B82Y30/00 , B41J2/1606
摘要: A method for treating a metallic oxide or metallic nitride ink jet printhead nozzle plate comprising stamping the front surface thereof with an anti-wetting agent using an elastomeric stamp.
摘要翻译: 一种用于处理金属氧化物或金属氮化物喷墨打印头喷嘴板的方法,包括使用弹性体印模将其前表面冲压成抗湿润剂。
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公开(公告)号:US06325490B1
公开(公告)日:2001-12-04
申请号:US09224533
申请日:1998-12-31
申请人: Zhihao Yang , Thomas L. Penner , Ravi Sharma
发明人: Zhihao Yang , Thomas L. Penner , Ravi Sharma
IPC分类号: B41J2135
CPC分类号: B41J2/1646 , B41J2/1433 , B41J2/1606 , B41J2/162 , B41J2/1625 , B41J2/1642 , B41J2202/03 , B82Y10/00 , B82Y30/00
摘要: An ink jet nozzle plate is provided comprising an outer surface having a self-assembled monolayer thereon comprising a mixture of at least one hydrophobic compound and at least one ionic compound, which monolayer renders the outer surface non-wetting with respect to aqueous ink solutions. In accordance with preferred embodiments, the self-assembled monolayers comprises a mixture of hydrophobic alkyl thiols and charged alkyl thiols. An advantage of coatings in accordance with the invention is that they provide improved non-wetting characteristics after contact with ink.
摘要翻译: 提供一种喷墨喷嘴板,其包括其上具有自组装单层的外表面,其上包含至少一种疏水化合物和至少一种离子化合物的混合物,所述单层使外表面相对于水性油墨溶液不润湿。 根据优选实施方案,自组装单层包含疏水性烷基硫醇和带电的烷基硫醇的混合物。 根据本发明的涂层的优点是它们在与油墨接触之后提供改善的非润湿特性。
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公开(公告)号:US06296344B1
公开(公告)日:2001-10-02
申请号:US09470813
申请日:1999-12-22
申请人: Ravi Sharma , Zhihao Yang , Thomas L. Penner
发明人: Ravi Sharma , Zhihao Yang , Thomas L. Penner
IPC分类号: B41J2165
CPC分类号: B82Y30/00 , B05D1/185 , B05D5/00 , B05D7/52 , B41J2/1606 , B41J2/162 , B41J2/164 , B82Y40/00
摘要: A method for replenishing fouled coatings on a nozzle plate for an ink jet printhead, the nozzle plate comprising the following layers in the order recited: i) a first monomolecular layer of an organic material having first and second functional groups, the first functional group of the first monomolecular layer being bound to the surface of the nozzle plate, and the second functional group of the first monomolecular layer being bound to a second monomolecular layer, and ii) the second monomolecular layer of an organic material having first and second functional groups, the first functional group of the second monomolecular layer being bound to the second functional group of the first monomolecular layer, and the second functional group of the second monomolecular layer being an anti-wetting group, the second monomolecular layer having been fouled; the method comprising A) unbinding the first functional group of the fouled second monomolecular layer so that it is no longer bound to the second functional group of the first monomolecular layer; B) removing the fouled second monomolecular layer; and C) reattaching a new, unfouled second monomolecular layer to the first monomolecular layer; the new, unfouled second monomolecular layer comprising an organic material having first and second functional groups, the first functional group of the second new, unfouled monomolecular layer being bound to the second functional group of the first monomolecular layer, and the second functional group of the new, unfouled second monomolecular layer being an anti-wetting group.
摘要翻译: 一种用于在用于喷墨打印头的喷嘴板上补充污垢涂层的方法,喷嘴板按照所述顺序包括以下层:i)具有第一和第二官能团的有机材料的第一单分子层,第一官能团 所述第一单分子层与所述喷嘴板的表面结合,并且所述第一单分子层的第二官能团与第二单分子层结合,以及ii)具有第一和第二官能团的有机材料的第二单分子层, 第二单分子层的第一官能团与第一单分子层的第二官能团结合,第二单分子层的第二官能团为防润湿基团,第二单分子层已被污染; 所述方法包括:A)使结垢的第二单分子层的第一官能团与第一单分子层的第二官能团不再结合, B)去除被污染的第二单分子层; 和C)将新的未结合的第二单分子层重新附着到第一单分子层; 新的未结合的第二单分子层包含具有第一和第二官能团的有机材料,第二新的未结合单分子层的第一官能团与第一单分子层的第二官能团结合,第二官能团 新的未结垢的第二单分子层是抗潮湿组。
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公开(公告)号:US06193352B1
公开(公告)日:2001-02-27
申请号:US09204600
申请日:1998-12-03
IPC分类号: B41J2165
CPC分类号: B41J2/16552
摘要: A method for cleaning an ink jet print head nozzle plate having an anti-wetting layer formed thereon, wherein an aqueous solution of a metal salt of a taurine surfactant is applied to the nozzle plate and then removed.
摘要翻译: 一种用于清洁其上形成有防润湿层的喷墨打印头喷嘴板的方法,其中将牛磺酸表面活性剂的金属盐的水溶液施加到喷嘴板上,然后除去。
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公开(公告)号:US06361932B1
公开(公告)日:2002-03-26
申请号:US09151916
申请日:1998-09-11
IPC分类号: G03C112
CPC分类号: G03C1/29
摘要: This invention comprises a silver halide photographic material comprising at least one silver halide emulsion comprising silver halide grains having associated therewith at least two dye layers comprising (a) an inner dye layer adjacent to the silver halide grain and comprising at least one dye, Dye 1, that is capable of spectrally sensitizing silver halide and (b) an outer dye layer adjacent to the inner dye layer and comprising at least one dye, Dye 2, wherein Dye 2 is other than a cyanine dye, wherein the dye layers are held together by non-covalent forces; the outer dye layer adsorbs light at equal or higher energy than the inner dye layer; and the energy emission wavelength of the outer dye layer overlaps with the energy absorption wavelength of the inner dye layer. This invention also comprises a silver halide photographic material comprising at least one silver halide emulsion comprising silver halide grains having associated therewith at least one dye having at least one anionic substituent and at least one dye having at least one cationic substituent, with the proviso that one of the dyes is other than a cyanine dye.
摘要翻译: 本发明包括卤化银照相材料,其包含至少一种包含卤化银颗粒的卤化银乳剂,所述卤化银颗粒具有至少两个染料层,所述染料层包含(a)与卤化银颗粒相邻的内部染料层,并且包含至少一种染料染料1 能够对卤化银进行光谱增感和(b)与内部染料层相邻的外部染料层,并且包括至少一种染料染料2,其中染料2不是花青染料,其中染料层保持在一起 非共同力量; 外染料层以等于或高于内染料层的能量吸收光; 并且外部染料层的能量发射波长与内部染料层的能量吸收波长重叠。本发明还包括卤化银照相材料,其包含至少一种卤化银乳剂,其包含与其相关联的至少一种染料, 至少一个阴离子取代基和至少一种具有至少一个阳离子取代基的染料,条件是染料之一不是花青染料。
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公开(公告)号:US5247602A
公开(公告)日:1993-09-21
申请号:US914163
申请日:1992-07-14
申请人: Thomas L. Penner , Douglas R. Robello , Nancy J. Armstrong , David J. Williams , Matthew C. Ezenyilimba
发明人: Thomas L. Penner , Douglas R. Robello , Nancy J. Armstrong , David J. Williams , Matthew C. Ezenyilimba
CPC分类号: B82Y20/00 , G02F1/3618 , G02F1/377 , G02F1/065 , G02F2202/027 , Y10T428/31504
摘要: An optical article is disclosed comprised of a support including a portion adjacent one major surface which is transparent to the electromagnetic radiation sought to be propagated, an organic layer unit capable of converting a portion of polarized electromagnetic radiation of a selected wavelength to its second harmonic wavelength, means for optically coupling into said organic layer unit polarized electromagnetic radiation of a selected wavelength in its zero order transverse magnetic mode, and means for receiving from the layer unit a portion of the electromagnetic radiation in the form of a first order transverse magnetic mode. The organic layer unit has a thickness which is at least 70 percent cf the wavelength of the zero order transverse magnetic mode and differs by less than 100 .ANG. from the thickness required for identical propagation constants of the zero and first order transverse magnetic modes. The organic layer unit is comprised of a Y-type Langmuir-Blodgett assembly of amphiphiles forming a first Langmuir Blodgett layer unit containing noncentrosymmetric organic molecular dipoles of a first orientation providing a second order polarization susceptibility to the first layer unit in excess of 10.sup.-9 electrostatic units, and a Y-type Langmuir-Blodgett assembly of amphiphiles forming a second Langmuir-Blodgett layer unit adapted to be coated on the first Langmuir-Blodgett layer unit containing noncentro-symmetric organic molecular dipoles of a second orientation providing a second order polarization susceptibility to the second layer unit in excess of 10.sup.-9 electrostatic units, but of opposite sign to that of the first layer unit.
摘要翻译: 公开了一种光学制品,其包括支撑件,该支撑件包括邻近被试传播的电磁辐射透明的一个主表面的部分,能够将所选波长的偏振电磁辐射的一部分转换成其二次谐波波长的有机层单元 用于以其零级横向磁模式光学耦合到选定波长的有机层单元极化电磁辐射的装置,以及用于从层单元接收一阶横向磁模式形式的电磁辐射的一部分的装置。 有机层单元的厚度至少为零级横向磁模的波长的70%,并且与零和一级横向磁模的相同传播常数所需的厚度相差小于100安培。 有机层单元由形成第一Langmuir Blodgett层单元的Y型Langmuir-Blodgett组件组成,其包含第一取向的非中心对称有机分子偶极子,其提供超过10-9的第一层单元的二阶极化敏感性 静电单元和形成第二Langmuir-Blodgett层单元的Y型Langmuir-Blodgett组件,其适于涂覆在第一Langmuir-Blodgett层单元上,所述第一Langmuir-Blodgett层单元包含提供二阶极化的第二取向的非对称有机分子偶极子 对第二层单元的敏感性超过10-9静电单位,但与第一层单元的相反。
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