Method for decreasing the foam formation during cultivation of a microorganism
    1.
    发明授权
    Method for decreasing the foam formation during cultivation of a microorganism 失效
    在微生物培养期间减少泡沫形成的方法

    公开(公告)号:US07338779B1

    公开(公告)日:2008-03-04

    申请号:US10050000

    申请日:2000-08-21

    IPC分类号: C12P39/00

    摘要: This invention relates to a method for decreasing the foam formation during cultivation of a microorganism and to a method for producing an enhanced amount of a product of interest. The method comprises that the microorganism is modified in such a way that the microorganism does not produce an essential amount of at least one of the proteins, polypeptides or peptides associated with foam formation during cultivation of the unmodified microorganism. In particular the method comprises that the microorganism is modified not to produce an essential amount of amphipathic or hydrophobic proteins, polypeptides or peptides.

    摘要翻译: 本发明涉及一种降低微生物培养过程中泡沫形成的方法及其生产方法。 该方法包括微生物的修饰,使得微生物在培养未修饰的微生物期间不产生必需量的至少一种与泡沫形成相关的蛋白质,多肽或肽中的至少一种。 特别地,该方法包括修饰微生物不产生必需量的两亲性或疏水性蛋白质,多肽或肽。