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公开(公告)号：US11999987B2
公开(公告)日：2024-06-04
申请号：US17206943
申请日：2021-03-19
发明人： James L. Steele , Brooks Henningsen , Jeffery R. Broadbent , Ekkarat Phrommao , Fernanda Cristina Firmino
IPC分类号： C12P39/00 , C07K14/335 , C12N1/20 , C12P7/06
CPC分类号： C12P39/00 , C07K14/335 , C12N1/20 , C12P7/06 , C12Y101/01001 , C12Y401/01001
摘要： The present disclosure concerns a co-culture of bacterial cells for making a fermented product from a biomass. The co-culture comprising a first recombinant lactic acid bacteria (LAB) cell expressing at least one bacteriocin and a second recombinant lactic acid bacteria (LAB) cell capable of converting, at least in part, the biomass into the fermented product. The second recombinant LAB cell is immune to the bacteriocin produced by the first recombinant LAB cell. The co-culture can be used, optionally in combination with a yeast host cell, to make a fermented product. The present disclosure also provides processes for making the fermented product by using the co-culture as wells kits and media comprising the co-culture.
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公开(公告)号：US11999940B2
公开(公告)日：2024-06-04
申请号：US13844544
申请日：2013-03-15
IPC分类号： C12M1/36 , C05F17/20 , C05F17/50 , C12M1/00 , C12M1/107 , C12M1/12 , C12N1/20 , C12P3/00 , C12P5/02 , C12P7/40 , C12P39/00
CPC分类号： C12M41/48 , C05F17/20 , C05F17/50 , C12M21/04 , C12M23/58 , C12M25/18 , C12M29/02 , C12M47/06 , C12N1/20 , C12P3/00 , C12P5/023 , C12P7/40 , C12P39/00 , Y02E50/30 , Y02P20/145 , Y02W10/37 , Y02W30/40
摘要： A system and method for the production of microbial consortiums and by-product material is provided. A physical containment system comprising phase spaces arranged in a discrete order to favor specific biological reactions is also provided. Phase profiles and phase data sets include the pre-determined physical and biological parameters for the phase space transitions. Movement of material from one phase to the next is hydraulically balanced enabling working fluid to continuously move in a fixed direction and rate of flow. Continuous monitoring of phase profiles and phase data sets provide feedback to the system enabling alteration of the conditions in the system to control reactions therein.
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公开(公告)号：US20230348950A1
公开(公告)日：2023-11-02
申请号：US17796487
申请日：2021-01-28
申请人： DSM IP ASSETS B.V.
发明人： Pim VAN HEE
IPC分类号： C12P39/00 , A23C9/123 , A23C19/06 , C12Q1/70 , C12Q1/6851
CPC分类号： C12P39/00 , A23C9/123 , A23C19/061 , C12Q1/701 , C12Q1/6851
摘要： A method, process, and computer program for determining an order in which a food product is successively cultured with a set of bacterial cultures in a process for producing a fermented food product, each bacterial culture of the set of bacterial cultures including at least one bacterial strain, wherein the set of bacterial cultures comprises a first subset of one or more bacterial cultures comprising one or more unknown bacterial strain, and a second subset of one or more bacterial cultures comprising one or more known bacterial strains, wherein each of the bacterial strains of the second subset is known; wherein the process is carried out with an initial order of the set of bacterial cultures; wherein during culturing with each bacterial culture of the first subset a process sample is collected, wherein a culture sample of a bacterial culture of the second subset is exposed to the collected process samples in order to determine bacteriophage sensitivities of the one or more bacterial cultures of the second subset to bacteriophages present in the collected process sample, wherein an adapted order of the set of bacterial cultures is determined based on the determined bacteriophage sensitivities such as to reduce common bacteriophage sensitivities in successive bacterial cultures.
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公开(公告)号：US11702711B2
公开(公告)日：2023-07-18
申请号：US17048512
申请日：2019-04-15
申请人： LUSBIO, INC.
发明人： Robert Bartek , Bahman Rejai
IPC分类号： B01J23/745 , C12P19/02 , C12P39/00 , C13K1/02 , C13K13/00
CPC分类号： C13K1/02 , B01J23/745 , C12P19/02 , C12P39/00 , C13K13/00 , C12P2201/00
摘要： A method for treating biomass including lignocellulosic polymers. The biomass is treated in a mixture of water with at least one oxidizing agent and steam at a temperature in a range of from about 130° C. to about 220° C. for a period from about 5 seconds to about 10 hours. The pH of the mixture is periodically measured for substantially an entire duration of the treating step. As necessary, based on the measured pH of the mixture, adjusting the pH of the mixture into a range of from about pH 4.5 to about pH 7.5 by adding a base to the mixture.
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公开(公告)号：US11623980B1
公开(公告)日：2023-04-11
申请号：US17752648
申请日：2022-05-24
IPC分类号： C08L1/04 , C12N1/14 , C12P19/04 , C12P1/02 , C12P39/00 , C12N1/20 , C12N1/04 , C12P1/04 , A01G18/20 , C12N1/22 , C12R1/645 , C12R1/02
摘要： A leather-like hybrid mycelial cellulose sheet and production thereof. Precise selection of mushroom species and reagents allows for production at low pH, thereby resulting in a strong, flexible, and dry leather-like material suitable for application in various industries.
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公开(公告)号：US20220340861A1
公开(公告)日：2022-10-27
申请号：US17743276
申请日：2022-05-12
IPC分类号： C12M1/36 , C12M1/00 , C12M1/12 , C12P7/40 , C12P5/02 , C12P3/00 , C12P39/00 , C12M1/107 , C05F17/20 , C05F17/50 , C12N1/20
摘要： A system and method for the production of microbial consortiums and by-product material is provided. A physical containment system comprising phase spaces arranged in a discrete order to favor specific biological reactions is also provided. Phase profiles and phase data sets include the pre-determined physical and biological parameters for the phase space transitions. Movement of material from one phase to the next is hydraulically balanced enabling working fluid to continuously move in a fixed direction and rate of flow. Continuous monitoring of phase profiles and phase data sets provide feedback to the system enabling alteration of the conditions in the system to control reactions therein.
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公开(公告)号：US20220315960A1
公开(公告)日：2022-10-06
申请号：US17647436
申请日：2022-01-07
发明人： Hsieh-Hsun HO , Ching-Wei CHEN , Yu-Fen HUANG , Chen-Hung HSU , Wen-Yang LIN , Yi-Wei KUO , Shin-Yu TSAI
IPC分类号： C12P13/00 , C12N1/20 , C12P39/00 , A23L33/135
摘要： A method for producing γ-aminobutyric acid includes cultivating, in a culture medium containing glutamic acid or a salt thereof, a probiotic composition including at least one lactic acid bacterial strain selected from the group consisting of Bifidobacterium breve CCFM1025 which is deposited at the Guangdong Microbial Culture Collection Center under an accession number GDMCC 60386, Lactobacillus acidophilus TYCA06, Lactobacillus plantarum LPL28, and Bifidobacterium longum subsp. infantis BLI-02 which are deposited at the China General Microbiological Culture Collection Center respectively under accession numbers CGMCC 15210, CGMCC 17954, and CGMCC 15212, Lactobacillus salivarius subsp. salicinius AP-32 which is deposited at the China Center for Type Culture Collection under an accession number CCTCC M 2011127, and combinations thereof.
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公开(公告)号：US20220248697A1
公开(公告)日：2022-08-11
申请号：US17432332
申请日：2019-08-12
IPC分类号： A23B4/20 , A23L3/3508 , C12P39/00 , C12P9/00
摘要： The present invention relates to an “Organic, Natural Antimicrobial preservative for Meat products” comprising of natural organic salts (majorly lactates and acetates) which are a completely safe, organic, natural ingredients for preventing spoilage of fresh meats and sausages under refrigeration and imparts an enhanced shelf life to the meat products. The present organic preservative is produced by a two-step microbial fermentation of reducing sugars extracted from sweet potato and cassava starches using plantarum” for the first anaerobic fermentation step followed by the second “aerobic fermentation” step by a bacterial “Lactobacillus consortium comprising of Saccharomyces cerevisiae and Acetobacter aceti followed by downstream purification steps. It imparts a long term preservation and shelf life to the meat products for a period of more than 20-25 days for fresh brined meat and more than 6-8 months for processed and cured, refrigerated meats.
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公开(公告)号：US20220243241A1
公开(公告)日：2022-08-04
申请号：US17620324
申请日：2020-06-15
发明人： Sean FARMER , Ken ALIBEK , Yajie CHEN
摘要： Methods are provided for enhanced production of microbial biosurfactants, the methods comprising co-cultivating Myxococcus xanthus and Pseudomonas chlororaphis. In certain embodiments, the biosurfactants are rhamnolipids or rhamnolipids-like glycolipids. In certain embodiments, other microbial growth by-products are produced, such as organic hydrocarbons including terpenes and/or terpenoids. Microbe-based products produced according to the subject methods are also provided, as well as their uses in, for example, agriculture, oil and gas recovery, and health care.
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公开(公告)号：US20220145350A1
公开(公告)日：2022-05-12
申请号：US17435530
申请日：2020-02-28
发明人： Gregory Bonito , Zhi-Yan Du
摘要： This application describes methods of using fungi to harvest algae. As illustrated herein the algae stick onto and are captured directly by the hyphae of the fungi. The fungi, the algae, or both can be modified to express heterologous proteins or other products. The methods facilitate harvesting of useful strains of algae and the products made by such algae.
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