公开(公告)号：US08362769B2

公开(公告)日：2013-01-29

申请号：US12564272

申请日：2009-09-22

申请人： Timothy Hughes ,  Vladimir Jellus ,  Michael Szimtenings

发明人： Timothy Hughes ,  Vladimir Jellus ,  Michael Szimtenings

IPC分类号： G01V3/00

CPC分类号： G01R33/4828 ,  G01R33/481

摘要： In a magnetic resonance method and system to automatically differentiate whether a pixel of an MR image acquired with magnetic resonance system originated from fat-dominated tissue or water-dominated tissue, only one spin echo-based magnetic resonance signal per pixel is acquired at a point in time at which the phase of a magnetic resonance signal of aqueous tissue has a phase opposite to the phase of a magnetic resonance signal of fat tissue. The phase angle of the pixel is then calculated, a base phase at the pixel depending on the magnetic resonance system is determined, and a corrected phase angle of the pixel is determined from the phase angle and the base phase. Whether the pixel originated from fat-dominated tissue or water-dominated tissue is then determined using the corrected phase angle of the pixel.

摘要翻译： 在磁共振方法和系统中，用于自动区分由磁共振系统获取的MR图像的像素是源自脂肪占主导的组织还是以水为主的组织，仅在每个像素点处仅获得一个基于自旋回波的磁共振信号 水分组织的磁共振信号的相位与脂肪组织的磁共振信号的相位相反的时间。 然后计算像素的相位角，确定取决于磁共振系统的像素处的基极相位，并且从相位角和基极相位确定像素的校正相位角。 然后使用像素的校正相位角来确定来自以脂肪为主的组织或以水为主的组织的像素。

公开(公告)号：US20100072998A1

公开(公告)日：2010-03-25

申请号：US12564272

申请日：2009-09-22

申请人： Timothy Hughes ,  Vladimir Jellus ,  Michael Szimtenings

发明人： Timothy Hughes ,  Vladimir Jellus ,  Michael Szimtenings

IPC分类号： G01R33/48

CPC分类号： G01R33/4828 ,  G01R33/481

摘要： In a magnetic resonance method and system to automatically differentiate whether a pixel of an MR image acquired with magnetic resonance system originated from fat-dominated tissue or water-dominated tissue, only one spin echo-based magnetic resonance signal per pixel is acquired at a point in time at which the phase of a magnetic resonance signal of aqueous tissue has a phase opposite to the phase of a magnetic resonance signal of fat tissue. The phase angle of the pixel is then calculated, a base phase at the pixel depending on the magnetic resonance system is determined, and a corrected phase angle of the pixel is determined from the phase angle and the base phase. Whether the pixel originated from fat-dominated tissue or water-dominated tissue is then determined using the corrected phase angle of the pixel.

摘要翻译： 在磁共振方法和系统中，用于自动区分由磁共振系统获取的MR图像的像素是源自脂肪占主导的组织还是以水为主的组织，仅在每个像素点处仅获得一个基于自旋回波的磁共振信号 水分组织的磁共振信号的相位与脂肪组织的磁共振信号的相位相反的时间。 然后计算像素的相位角，确定取决于磁共振系统的像素处的基极相位，并且从相位角和基极相位确定像素的校正相位角。 然后使用像素的校正相位角来确定来自以脂肪为主的组织或以水为主的组织的像素。

公开(公告)号：US08547094B2

公开(公告)日：2013-10-01

申请号：US12461902

申请日：2009-08-27

申请人： Vladimir Jellus ,  Michael Szimtenings

发明人： Vladimir Jellus ,  Michael Szimtenings

IPC分类号： G01R33/48

CPC分类号： G01R33/56563 ,  A61B6/037 ,  A61B6/5247 ,  G01R33/481 ,  G01R33/4828 ,  G01R33/543

摘要： A method is disclosed for determining an attenuation map for use in positron emission tomography and for the use of homogeneity information relating to the magnetic resonance magnetic field, in particular for the purpose of determining shim settings, within the scope of a single magnetic resonance image recording. In at least one embodiment of the method, a first and a second image data record are firstly recorded with a three-dimensional gradient echo sequence during a first and a second echo time, respectively, with the phase difference between the water and the fat signal amounting to zero during the first echo time and amounting to 180 degrees during the second echo time. The attenuation map is determined from fat/water ratios obtained from the image data records by way of a Dixon technology, in particular a 2-point Dixon technology. In at least one embodiment, all voxels with a signal intensity below a first threshold value are excluded at least for the second image data record by using a mask and only the non excluded voxels of the first and second image data record are taken into consideration in order to determine the homogeneity information from the phase differences of adjacent voxels.

摘要翻译： 公开了一种用于确定在正电子发射断层摄影中使用的衰减图和使用与磁共振磁场相关的均匀性信息的方法，特别是用于在单个磁共振图像记录的范围内确定垫片设置的目的 。 在该方法的至少一个实施例中，第一和第二图像数据记录首先在第一和第二回波时间期间被记录有三维梯度回波序列，水和脂肪信号之间的相位差 在第一回波时间期间为零，并且在第二回波时间期间达到180度。 通过Dixon技术，特别是2点Dixon技术，从图像数据记录获得的脂肪/水比确定衰减图。 在至少一个实施例中，至少对于第二图像数据记录通过使用掩码来排除具有低于第一阈值的信号强度的所有体素，并且仅考虑第一和第二图像数据记录的未排除的体素 从相邻体素的相位差来确定均匀性信息。

公开(公告)号：US20100052674A1

公开(公告)日：2010-03-04

申请号：US12461902

申请日：2009-08-27

申请人： Vladimir Jellus ,  Michael Szimtenings

发明人： Vladimir Jellus ,  Michael Szimtenings

IPC分类号： G01R33/48

CPC分类号： G01R33/56563 ,  A61B6/037 ,  A61B6/5247 ,  G01R33/481 ,  G01R33/4828 ,  G01R33/543

摘要： A method is disclosed for determining an attenuation map for use in positron emission tomography and for the use of homogeneity information relating to the magnetic resonance magnetic field, in particular for the purpose of determining shim settings, within the scope of a single magnetic resonance image recording. In at least one embodiment of the method, a first and a second image data record are firstly recorded with a three-dimensional gradient echo sequence during a first and a second echo time, respectively, with the phase difference between the water and the fat signal amounting to zero during the first echo time and amounting to 180 degrees during the second echo time. The attenuation map is determined from fat/water ratios obtained from the image data records by way of a Dixon technology, in particular a 2-point Dixon technology. In at least one embodiment, all voxels with a signal intensity below a first threshold value are excluded at least for the second image data record by using a mask and only the non excluded voxels of the first and second image data record are taken into consideration in order to determine the homogeneity information from the phase differences of adjacent voxels.

摘要翻译： 公开了一种用于确定在正电子发射断层摄影中使用的衰减图和使用与磁共振磁场有关的均匀性信息的方法，特别是用于在单个磁共振图像记录的范围内确定垫片设置的目的 。 在该方法的至少一个实施例中，第一和第二图像数据记录首先在第一和第二回波时间期间被记录有三维梯度回波序列，水和脂肪信号之间的相位差 在第一回波时间期间为零，并且在第二回波时间期间达到180度。 通过Dixon技术，特别是2点Dixon技术，从图像数据记录获得的脂肪/水比确定衰减图。 在至少一个实施例中，至少对于第二图像数据记录通过使用掩码来排除具有低于第一阈值的信号强度的所有体素，并且仅考虑第一和第二图像数据记录的未排除的体素 从相邻体素的相位差来确定均匀性信息。

公开(公告)号：US08195417B2

公开(公告)日：2012-06-05

申请号：US12219610

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

发明人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

IPC分类号： G01R35/00

CPC分类号： A61B6/032 ,  A61B5/11 ,  A61B5/7285 ,  A61B6/037 ,  A61B6/5247 ,  A61B6/541 ,  A61B8/00 ,  A61B8/4416 ,  A61B90/36 ,  A61B2090/364 ,  G06F19/00

摘要： Disclosed is a method and apparatus for recording measured data from a patient by taking movements into account by use of a medical device designed both for recording motion-related measured data and for recording nuclear medicine measured data. The method may include recording nuclear medicine measured data by use of the medical device, simultaneously recording motion-related measured data by use of the medical device, determining at least one motion information item relating to at least one movement of the patient and/or at least one movement inside the body of the patient during the ongoing measured data recording by evaluating at least a portion of the previously recorded motion-related measured data, and carrying out motion correction for at least a portion of the nuclear medicine measured data by use of the computational device in parallel with recording the measured data.

摘要翻译： 公开了一种通过使用设计用于记录运动相关测量数据和记录核医学测量数据的医疗装置来考虑运动来记录来自患者的测量数据的方法和装置。 该方法可以包括通过使用医疗装置记录核医学测量数据，同时通过使用医疗装置记录与运动有关的测量数据，确定与患者的至少一个运动有关的至少一个运动信息项和/或在 通过评估先前记录的运动相关测量数据的至少一部分，以及通过使用以下方式对至少一部分核医学测量数据执行运动校正，在进行中的测量数据记录期间在患者体内进行至少一次运动 计算设备并行记录测量数据。

公开(公告)号：US09636422B2

公开(公告)日：2017-05-02

申请号：US12219609

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Diana Martin ,  Günther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

发明人： Thorsten Feiweier ,  Diana Martin ,  Günther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

IPC分类号： A61K49/00 ,  A61B6/03 ,  A61B6/00 ,  A61B5/00

CPC分类号： A61K49/0004 ,  A61B5/4064 ,  A61B5/4088 ,  A61B6/037 ,  A61B6/5247

摘要： A computerized method is disclosed for detecting a brain region with neurodegenerative change and also a brain region with vascular change in the brain of a patient and also an imaging arrangement suitable for this. In at least one embodiment, the method includes recording a first data record of the brain via positron emission tomography and a second data record of the brain via magnetic resonance imaging; reconstructing a PET image from the first data record and an MRI image from the second data record; identifying evidence for a brain region with vascular change in the MRI image; segmenting the MRI image into gray matter and white matter; identifying a brain region with neurodegenerative change in the PET image; and superposing the PET image and the segmented MRI image to determine whether the brain region with neurodegenerative change is present in gray matter or in white matter, the recording of the first data record and the second data record being carried out in quick succession without repositioning the patient or is even carried out simultaneously.

公开(公告)号：US20090105583A1

公开(公告)日：2009-04-23

申请号：US12232522

申请日：2008-09-18

申请人： Diana Martin ,  Gunther Platsch ,  Martin Requardt ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

发明人： Diana Martin ,  Gunther Platsch ,  Martin Requardt ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

IPC分类号： A61B5/055 ,  A61G7/00 ,  G06Q50/00

CPC分类号： G01T1/1603 ,  A61B6/037 ,  A61B6/4494 ,  G01T7/005 ,  G06F19/00 ,  G06Q50/22 ,  G06Q50/24

摘要： A method is disclosed for determining attenuation values for PET data of a patient. In at least one embodiment, the method includes detecting at least one accessory of a magnetic resonance imaging scanner and detecting the position and/or alignment of the accessory by way of an imaging measuring method; comparing the detected accessory with data from a database; and assigning an attenuation map, which is contained in the database, to attenuation values of the detected accessory and adapting the attenuation map to the detected position and/or alignment of the accessory.

摘要翻译： 公开了一种用于确定患者PET数据的衰减值的方法。 在至少一个实施例中，该方法包括检测磁共振成像扫描仪的至少一个附件，并通过成像测量方法检测附件的位置和/或对准; 将检测到的附件与来自数据库的数据进行比较; 以及将包含在所述数据库中的衰减图分配给所检测到的附件的衰减值，并将所述衰减图适配到所述检测到的位置和/或所述附件的对准。

公开(公告)号：US20090041318A1

公开(公告)日：2009-02-12

申请号：US12219613

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

发明人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

IPC分类号： G01R33/56 ,  G01R33/54

CPC分类号： A61B6/032 ,  A61B5/11 ,  A61B5/7285 ,  A61B6/037 ,  A61B6/541 ,  A61B8/00 ,  A61B8/4416 ,  G06F19/00

摘要： A method is disclosed for recording measured data of a patient while taking account of movement operations by way of a medical device that is designed both for recording movement-related measured data, in particular measured data of high temporal resolution and/or measured data that can be interpolated with regard to movement operations, with the aid of an imaging method and/or by means of at least one sensor element, and also for recording nuclear medicine measured data, in particular of lower temporal resolution. In at least one embodiment, the method includes recording nuclear medicine measured data with the aid of the medical device; simultaneously recording movement-related measured data with the aid of the medical device; determining at least one item of movement information relating to at least one movement operation of the patient and/or in the body of the patient by evaluating at least a portion of the recorded measured data of high temporal resolution on the part of a computing device of the medical device; and adapting at least one item of attenuation correction information available for the computing device and serving for reconstructing the nuclear medicine measured data, doing so as a function of the at least one determined item of movement information.

摘要翻译： 公开了一种用于记录患者的测量数据的方法，同时考虑到通过设计用于记录运动相关测量数据的医疗设备，特别是高时间分辨率的测量数据和/或可测量数据的测量数据， 借助于成像方法和/或通过至少一个传感器元件，以及用于记录核医学测量数据，特别是用于记录较低时间分辨率的内插关于移动操作。 在至少一个实施例中，该方法包括借助医疗装置记录核医学测量数据; 借助医疗设备同时记录运动相关测量数据; 通过在计算设备的一部分上评估所记录的高时间分辨率测量数据的至少一部分来确定与患者的至少一个移动操作和/或患者身体有关的至少一个移动信息项 医疗器械; 以及修改可用于所述计算设备的至少一项衰减校正信息，并且用于重构所述核医学测量数据，作为所述至少一个确定的运动信息项的函数。

公开(公告)号：US20090018431A1

公开(公告)日：2009-01-15

申请号：US12216293

申请日：2008-07-02

申请人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

发明人： Thorsten Feiweier ,  Diana Martin ,  Gunther Platsch ,  Sebastian Schmidt ,  Kristin Schmiedehausen ,  Michael Szimtenings

IPC分类号： A61B5/05

CPC分类号： G01R33/481 ,  A61B5/0035 ,  A61B5/04008 ,  A61B5/4094 ,  A61B6/037 ,  A61B6/501 ,  A61B6/5247

摘要： A method and an apparatus are disclosed for imaging functional processes in the brain. In order to be able to correlate the results of MEG examinations with anatomical information and metabolic data, a positron emission tomography measurement is recorded in at least one embodiment by at least one radiation detector, a magnetic resonance imaging measurement is recorded by a coil and a radio-frequency antenna device and a magnetoencephalography measurement is recorded by a plurality of magnetic field sensors, the positron emission tomography measurement and the magnetic resonance imaging measurement being substantially undertaken at the same time, so that the records of the positron emission tomography measurement and the magnetic resonance tomography measurement are isocentric. In at least one embodiment, an evaluation apparatus is provided for carrying out a spatial correlation between the magnetoencephalography measurement and the magnetic resonance imaging measurement, so that registration between the magnetoencephalography measurement and the positron emission tomography measurement results.

摘要翻译： 公开了一种用于成像脑中的功能过程的方法和装置。 为了能够将MEG检查的结果与解剖信息和代谢数据相关联，在至少一个实施例中通过至少一个辐射检测器记录正电子发射断层摄影测量，磁共振成像测量由线圈和 射频天线装置和脑磁图测量由多个磁场传感器记录，正电子发射断层摄影测量和磁共振成像测量基本上同时进行，使得正电子发射断层摄影测量和 磁共振断层扫描测量是同中心的。 在至少一个实施例中，提供了一种用于执行脑磁图测量和磁共振成像测量之间的空间相关性的评估装置，从而导致脑磁图测量与正电子发射断层摄影测量之间的配准。

公开(公告)号：US20090005678A1

公开(公告)日：2009-01-01

申请号：US12213745

申请日：2008-06-24

申请人： Kristin Schmiedehausen ,  Gunther Platsch ,  Thorsten Feiweier ,  Diana Martin ,  Sebastian Schmidt ,  Michael Szimtenings

发明人： Kristin Schmiedehausen ,  Gunther Platsch ,  Thorsten Feiweier ,  Diana Martin ,  Sebastian Schmidt ,  Michael Szimtenings

IPC分类号： A61B6/03

CPC分类号： A61B6/501 ,  A61B6/037 ,  A61B6/507 ,  A61B34/10 ,  A61B90/36 ,  A61B2090/364 ,  A61B2090/374

摘要： A computer-implemented method is disclosed for determining and displaying an access corridor to a target area in the brain of a patient, as well as an imaging arrangement suited to this. In at least one embodiment, the method includes a) generating a first image of the brain via positron emission tomography, b) discriminating the target area relative to its surroundings via electronic image processing, c) generating a second image of the brain via magnetic resonance imaging while acquiring at least one anatomical structure, d) generating a third image of the brain via an imaging method displaying physiological processes for identifying at least one functional area of the brain that must not be injured in any circumstances, e) determining an access corridor to the target area while omitting the at least one functional area of the brain, and f) generating and displaying a fourth image of the brain in which the target area, the at least one functional area of the brain, the at least one anatomical structure and the access corridor are displayed, wherein steps a) to d) are carried out, one after another in quick succession, in a single frame of reference without repositioning the patient, or are even carried out simultaneously.

摘要翻译： 公开了一种计算机实现的方法，用于确定和显示患者脑中的目标区域的通道走廊以及适合于此的成像装置。 在至少一个实施例中，该方法包括：a）通过正电子发射断层摄影术产生脑的第一图像，b）通过电子图像处理区分相对于其周围的目标区域，c）通过磁共振产生大脑的第二图像 成像，同时获取至少一个解剖结构，d）通过显示生理过程的成像方法产生大脑的第三图像，用于识别在任何情况下不得受伤的脑的至少一个功能区域，e）确定通路走廊 到目标区域，同时省略脑的至少一个功能区域，以及f）产生和显示脑的第四图像，其中目标区域，脑的至少一个功能区域，至少一个解剖结构 并且显示进入通道，其中步骤a）至d）在一个单独的参考框架中以快速连续的方式相继地执行而不重新定位 或者甚至同时进行。