BK beta subunits of Slo family potassium channels
    2.
    发明申请
    BK beta subunits of Slo family potassium channels 失效
    Slo家族钾通道的BKβ亚基

    公开(公告)号:US20060004187A1

    公开(公告)日:2006-01-05

    申请号:US11219359

    申请日:2005-09-02

    IPC分类号: C07K14/705 C12Q1/68 C07H21/04

    CPC分类号: C07K14/705

    摘要: The invention provides isolated nucleic acid and amino acid sequences of BK beta 2, BK beta 3, and BK beta 4, antibodies to the BK beta subunits, methods of detecting the BK beta subunits, methods of screening for modulators of Slo potassium channels comprising BK beta subunits, and kits for screening for activators and inhibitors of the Slo family potassium channels comprising BK beta subunits.

    摘要翻译: 本发明提供了BKβ2,BKβ3和BKβ4的分离的核酸和氨基酸序列,BKβ亚基的抗体,检测BKβ亚基的方法,筛选包含BK的Slo钾通道调节剂的方法 β亚基和用于筛选包含BKβ亚基的Slo家族钾通道的激活剂和抑制剂的试剂盒。

    BK beta subunits of Slo family potassium channels
    3.
    发明授权
    BK beta subunits of Slo family potassium channels 失效
    Slo家族钾通道的BKβ亚基

    公开(公告)号:US06994968B1

    公开(公告)日:2006-02-07

    申请号:US09914053

    申请日:2000-02-22

    IPC分类号: C12Q1/68 C12P21/06 C07K14/00

    CPC分类号: C07K14/705

    摘要: The invention provides isolated nucleic acid and amino sequences of BK beta 2, BK beta 3, and BK beta 4, antibodies to the BK beta subunits, methods of detecting the BK beta subunits, methods of screening for modulators of Slo family potassium channels comprising BK beta subunits.

    摘要翻译: 本发明提供了BKβ2,BKβ3和BKβ4的分离的核酸和氨基序列,BKβ亚基的抗体,检测BKβ亚基的方法,筛选包含BK的Slo家族钾通道调节剂的方法 β亚基。

    Beta subunits of Slo family potassium channels
    4.
    发明授权
    Beta subunits of Slo family potassium channels 失效
    Slo家族钾通道的β亚基

    公开(公告)号:US06432645B1

    公开(公告)日:2002-08-13

    申请号:US09510257

    申请日:2000-02-22

    IPC分类号: C12Q168

    CPC分类号: C07K14/705

    摘要: The invention provides isolated nucleic acid and amino acid sequences of BK beta 2, BK beta 3, and BK beta 4, antibodies to the BK beta subunits, methods of detecting the BK beta subunits, methods of screening for modulators of Slo potassium channels comprising BK beta subunits, and kits for screening for activators and inhibitors of the Slo family potassium channels comprising BK beta subunits.

    摘要翻译: 本发明提供了BKβ2,BKβ3和BKβ4的分离的核酸和氨基酸序列,BKβ亚基的抗体,检测BKβ亚基的方法,筛选包含BK的Slo钾通道调节剂的方法 β亚基和用于筛选包含BKβ亚基的Slo家族钾通道的激活剂和抑制剂的试剂盒。

    BK beta subunits of Slo family potassium channels
    5.
    发明授权
    BK beta subunits of Slo family potassium channels 失效
    Slo家族钾通道的BKβ亚基

    公开(公告)号:US07351553B2

    公开(公告)日:2008-04-01

    申请号:US11219359

    申请日:2005-09-02

    IPC分类号: C12P21/06

    CPC分类号: C07K14/705

    摘要: The invention provides isolated nucleic acid and amino acid sequences of BK beta 2, BK beta 3, and BK beta 4, antibodies to the BK beta subunits, methods of detecting the BK beta subunits, methods of screening for modulators of Slo potassium channels comprising BK beta subunits, and kits for screening for activators and inhibitors of the Slo family potassium channels comprising BK beta subunits.

    摘要翻译: 本发明提供了BKβ2,BKβ3和BKβ4的分离的核酸和氨基酸序列,BKβ亚基的抗体,检测BKβ亚基的方法,筛选包含BK的Slo钾通道调节剂的方法 β亚基和用于筛选包含BKβ亚基的Slo家族钾通道的激活剂和抑制剂的试剂盒。

    Human elk a voltage-gated potassium channel subunit
    6.
    发明授权
    Human elk a voltage-gated potassium channel subunit 失效
    人类麋鹿是一个电压门控钾通道亚基

    公开(公告)号:US06413741B1

    公开(公告)日:2002-07-02

    申请号:US09343494

    申请日:1999-06-30

    IPC分类号: C12N1512

    摘要: The invention provides isolated nucleic acid and amino acid sequences of hElk, antibodies to hElk, methods of detecting hElk, methods of screening for voltage-gated potassium channel activators and inhibitors using biologically active hElk, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising hElk.

    摘要翻译: 本发明提供hElk的分离的核酸和氨基酸序列,hElk的抗体,检测hElk的方法,筛选电压门控的钾通道激活剂的方法和使用生物活性的hElk的抑制剂,以及用于筛选激活剂和电压 - 门控钾通道包括hElk。

    Antibodies to human Elk, a voltage-gated potassium channel subunit
    7.
    发明授权
    Antibodies to human Elk, a voltage-gated potassium channel subunit 失效
    人类Elk抗体,电压门控钾通道亚单位

    公开(公告)号:US07355009B2

    公开(公告)日:2008-04-08

    申请号:US10966297

    申请日:2004-10-15

    IPC分类号: C07K16/28

    摘要: The invention provides isolated nucleic acid and amino acid sequences of hElk, antibodies to hElk, methods of detecting hElk, methods of screening for voltage-gated potassium channel activators and inhibitors using biologically active hElk, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising hElk.

    摘要翻译: 本发明提供hElk的分离的核酸和氨基酸序列,hElk的抗体,检测hElk的方法,筛选电压门控的钾通道激活剂的方法和使用生物活性的hElk的抑制剂,以及用于筛选激活剂和电压 - 门控钾通道包括hElk。

    Human Elk, a voltage-gated potassium channel subunit
    8.
    发明授权
    Human Elk, a voltage-gated potassium channel subunit 失效
    人类麋鹿,电压门控钾通道亚基

    公开(公告)号:US06833440B2

    公开(公告)日:2004-12-21

    申请号:US10160224

    申请日:2002-05-28

    IPC分类号: C07K1400

    摘要: The invention provides isolated nucleic acid and amino acid sequences of hElk, antibodies to hElk, methods of detecting hElk, methods of screening for voltage-gated potassium channel activators and inhibitors using biologically active hElk, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising hElk.

    摘要翻译: 本发明提供hElk的分离的核酸和氨基酸序列,hElk的抗体,检测hElk的方法,筛选电压门控的钾通道激活剂的方法和使用生物活性的hElk的抑制剂,以及用于筛选激活剂和电压 - 门控钾通道包括hElk。