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公开(公告)号：US09616248B2
公开(公告)日：2017-04-11
申请号：US13559518
申请日：2012-07-26
Applicant: Eric Meier , Timothy P. Mate , J. Nelson Wright , Steven C. Dimmer , Lynn M. Purdy
Inventor： Eric Meier , Timothy P. Mate , J. Nelson Wright , Steven C. Dimmer , Lynn M. Purdy
CPC classification number: A61N5/1039 , A61N5/1049 , A61N5/1067 , A61N5/107 , A61N2005/1051
Abstract: An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy.
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公开(公告)号：US08437449B2
公开(公告)日：2013-05-07
申请号：US11189431
申请日：2005-07-25
Applicant: James K. Riley , Eric Meier , J. Nelson Wright , Steven C. Dimmer , Timothy P. Mate
Inventor： James K. Riley , Eric Meier , J. Nelson Wright , Steven C. Dimmer , Timothy P. Mate
CPC classification number: A61N5/1038 , A61N5/103 , A61N5/1048
Abstract: A facility for facilitating custom radiation treatment planning is described. During a distinguished radiation treatment session for a patient, the facility collects data indicating positioning of a predefined treatment site of the patient relative to a target treatment location throughout the distinguished radiation treatment session. The facility associates the collected positioning data with data describing one or more other aspects of the distinguished radiation treatment session. The facility provides the associated data to a treatment planning facility to determine a treatment plan for future radiation treatment sessions for the patient.
Abstract translation: 描述了一种便于定制辐射治疗计划的设施。 在针对患者的不同的辐射治疗期间，设施收集指示患者相对于目标治疗位置在整个识别的辐射治疗期间的定位的数据。 该设施将收集的定位数据与描述不同的辐射治疗会话的一个或多个其他方面的数据相关联。 该设施将相关数据提供给治疗计划设施，以确定患者将来的放射治疗期间的治疗计划。
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公开(公告)号：US09943704B1
公开(公告)日：2018-04-17
申请号：US12563084
申请日：2009-09-18
Applicant: Timothy P. Mate , Tricia V. Zeller , Steven C. Dimmer , Fergus Quigley
Inventor： Timothy P. Mate , Tricia V. Zeller , Steven C. Dimmer , Fergus Quigley
CPC classification number: A61N5/1049 , A61B34/20 , A61B90/39 , A61B2034/2051 , A61B2090/101 , A61B2090/3908 , A61B2090/3958 , A61B2090/3975 , A61B2090/3987 , A61N5/1014 , A61N2005/1051
Abstract: Method and system fiducials contained in removable a device for use in guided radiation therapy treatment. One embodiment includes an active marker configured to be pre-loaded into a catheter for removeably implanting in the tissue of a patient. Another embodiment of the implantable device includes a stability element coupled to the marker and further coupled to an explant line. In some embodiments, the stability element is configured to hold the marker at a fixed location within the catheter (e.g., known location) with respect to a target in the tissue. In other embodiments, the explant line has a first portion coupled to the marker and/or the stability element and a second portion configured to be at least proximate to the dermis of the patient.
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公开(公告)号：US09682253B2
公开(公告)日：2017-06-20
申请号：US11190193
申请日：2005-07-25
Applicant: Eric Meier , Timothy P. Mate , J. Nelson Wright , Steven C. Dimmer , Lynn M. Purdy
Inventor： Eric Meier , Timothy P. Mate , J. Nelson Wright , Steven C. Dimmer , Lynn M. Purdy
CPC classification number: A61N5/1039 , A61N5/1049 , A61N5/1067 , A61N5/107 , A61N2005/1051
Abstract: An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.
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5.发明申请INTEGRATED RADIATION THERAPY SYSTEMS AND METHODS FOR TREATING A TARGET IN A PATIENT 有权综合辐射治疗系统和治疗患者目标的方法公开(公告)号：US20130172657A1
公开(公告)日：2013-07-04
申请号：US13559518
申请日：2012-07-26
Applicant: Eric Meier , Timothy P. Mate , J. Nelson Wright , Steven C. Dimmer , Lynn M. Purdy
Inventor： Eric Meier , Timothy P. Mate , J. Nelson Wright , Steven C. Dimmer , Lynn M. Purdy
IPC: A61N5/10
CPC classification number: A61N5/1039 , A61N5/1049 , A61N5/1067 , A61N5/107 , A61N2005/1051
Abstract: An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy.
Abstract translation: 综合放射治疗过程包括通过使用定位模式周期性地定位位于患者内的标记来获取与患者内的目标参数有关的第一目标目标数据。 该方法继续通过周期性地定位标记来获得与目标参数相关的第二目标目标数据。 第一目标数据可以在离开包含用于产生用于治疗患者的电离辐射束的辐射递送装置的第二区域的第一区域中获取。 第一和第二区域的定位方式可以相同。 在其他实施例中，可以使用使用第一能量类型来识别标记的第一定位模态来获取第一目标数据，并且可以使用使用第二能量的第二定位模态来获得第二目标数据。
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Patent Agency Ranking
公开(公告)号：US07657303B2
公开(公告)日：2010-02-02
申请号：US10743531
申请日：2003-12-22
Applicant: Timothy P. Mate , Steven C. Dimmer
Inventor： Timothy P. Mate , Steven C. Dimmer
CPC classification number: A61N5/1049 , A61B34/20 , A61B2034/2051 , A61B2034/2072 , A61B2090/3958 , A61N5/107 , A61N2005/105 , A61N2005/1051
Abstract: A system and method for accurately locating and tracking the position of a target, such as a tumor or the like, within a body. In one embodiment, the system is a target locating and monitoring system usable with a radiation delivery source that delivers selected doses of radiation to a target in a body. The system includes one or more excitable markers positionable in or near the target, an external excitation source that remotely excites the markers to produce an identifiable signal, and a plurality of sensors spaced apart in a known geometry relative to each other. A computer is coupled to the sensors and configured to use the marker measurements to identify a target isocenter within the target. The computer compares the position of the target isocenter with the location of the machine isocenter. The computer also controls movement of the patient and a patient support device so the target isocenter is co-incident with the machine isocenter before and during radiation therapy.
Abstract translation: 一种用于在身体内准确定位和跟踪诸如肿瘤等的靶的位置的系统和方法。 在一个实施例中，该系统是可与辐射递送源一起使用的目标定位和监测系统，其将选定剂量的辐射递送到身体中的目标。 该系统包括可定位在靶内或附近的一个或多个可激发标记，远程激发标记以产生可识别信号的外部激发源以及以已知几何形状相对于彼此间隔开的多个传感器。 计算机耦合到传感器并且被配置为使用标记测量来识别目标内的目标等角点。 计算机将目标等角点的位置与机器等角点的位置进行比较。 计算机还控制患者和患者支撑装置的运动，使得靶放射线与放射治疗之前和放射治疗期间的机器等角点共同入射。
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7.发明申请Systems and Methods for Treating a Patient Using Guided Radiation Therapy or Surgery 审中-公开使用引导性放射治疗或手术治疗患者的系统和方法公开(公告)号：US20090209852A1
公开(公告)日：2009-08-20
申请号：US11817383
申请日：2006-03-02
Applicant: Timothy P. Mate , Steven C. Dimmer , Laurence J. Newell , J. Nelson Wright
Inventor： Timothy P. Mate , Steven C. Dimmer , Laurence J. Newell , J. Nelson Wright
CPC classification number: A61B90/16 , A61B34/20 , A61B34/25 , A61B90/14 , A61B90/39 , A61B2034/2051 , A61B2090/101 , A61B2090/363 , A61B2090/374 , A61B2090/3975 , A61B2090/3995
Abstract: Systems and methods for locating and tracking a target, i.e., measuring the position and/or rotation of a target during setup and treatment of a patient in guided radiation therapy applications for the head and neck. One embodiment is directed toward a device having a body and markers, such as excitable transponders and/or radiographic fiducials, fixable in or on the body for localizing the body. For example, the body can be a mouthpiece body having a channel configured to receive a patient's teeth such that the mouthpiece is repeatedly and consistently placed in the same relative position in the patient when the patient bites down on the mouthpiece. The transponders can be alternating magnetic transponders and the fiducials can be gold seeds. Other embodiments include a device having a two-piece body, a first piece of the body having excitable transponders and a second piece of the body having radiographic fiducials.
Abstract translation: 用于定位和跟踪目标的系统和方法，即在用于头颈部的引导放射治疗应用中，在患者的建立和治疗期间测量目标的位置和/或旋转。 一个实施例涉及具有身体和标记的装置，例如可固定在身体中或身体上的可兴奋的应答器和/或射线照相基准体，用于使身体定位。 例如，身体可以是具有通道的接口管体，该通道被配置为接收患者的牙齿，使得当患者咬在嘴件上时，接口管被重复且一致地放置在患者的相同相对位置。 应答器可以是交替磁转发器，基准可以是金种子。 其他实施例包括具有两件式主体的装置，具有可兴奋的应答器的本体的第一部分和具有放射照相基准的本体的第二部分。
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8.发明授权公开(公告)号：US10195464B2
公开(公告)日：2019-02-05
申请号：US11165843
申请日：2005-06-24
Applicant: Edward J. Vertatschitsch , Steven C. Dimmer , Timothy P. Mate , Eric Meier , Keith Seiler , J. Nelson Wright
Inventor： Edward J. Vertatschitsch , Steven C. Dimmer , Timothy P. Mate , Eric Meier , Keith Seiler , J. Nelson Wright
Abstract: Systems and methods for treating a lung of a patient. One embodiment of a method comprises positioning a leadless marker in the lung of the patient relative to the target, and collecting position data of the marker. This method further comprises determining the location of the marker in an external reference frame outside of the patient based on the collected position data, and providing an objective output in the external reference frame that is responsive to movement of the marker. The objective output is provided at a frequency (i.e., periodicity) that results in a clinically acceptable tracking error. In addition, the objective output can also be provided at least substantially contemporaneously with collecting the position data used to determine the location of the marker.
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公开(公告)号：US09072895B2
公开(公告)日：2015-07-07
申请号：US12891742
申请日：2010-09-27
Applicant: Timothy P. Mate , Steven C. Dimmer
Inventor： Timothy P. Mate , Steven C. Dimmer
CPC classification number: A61N5/1049 , A61B34/20 , A61B2034/2051 , A61B2034/2072 , A61B2090/3958 , A61N5/107 , A61N2005/105 , A61N2005/1051
Abstract: A system and method for accurately locating and tracking the position of a target, such as a tumor or the like, within a body. In one embodiment, the system is a target locating and monitoring system usable with a radiation delivery source that delivers a selected doses of radiation to a target in a body. The system includes one or more excitable beacons positionable in or near the target, an external excitation source that remotely excites the beacons to produce an identifiable signal, and a plurality of sensors spaced apart in a known geometry relative to each other. A computer is coupled to the sensors and configured to use the beacon measurements to identify a target isocenter within the target. The computer compares the position of the target isocenter with the location of the machine isocenter. The computer also controls movement of the patient and a patient support device so the target isocenter is coincident with the machine isocenter before and during radiation therapy.
Abstract translation: 一种用于在身体内准确定位和跟踪诸如肿瘤等的靶的位置的系统和方法。 在一个实施例中，该系统是可与辐射递送源一起使用的目标定位和监测系统，其将选定剂量的辐射递送到身体中的目标。 该系统包括可定位在目标中或附近的一个或多个可激励信标，远程激发信标以产生可识别信号的外部激励源以及以已知几何形状相对于彼此间隔开的多个传感器。 计算机耦合到传感器并且被配置为使用信标测量来识别目标内的目标等角点。 计算机将目标等角点的位置与机器等角点的位置进行比较。 计算机还控制患者和患者支撑装置的运动，使得靶放射线与放射治疗之前和放射治疗期间的机器等角点重合。
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公开(公告)号：US20110046481A1
公开(公告)日：2011-02-24
申请号：US12891742
申请日：2010-09-27
Applicant: Timothy P. Mate , Steven C. Dimmer
Inventor： Timothy P. Mate , Steven C. Dimmer
IPC: A61B6/00
CPC classification number: A61N5/1049 , A61B34/20 , A61B2034/2051 , A61B2034/2072 , A61B2090/3958 , A61N5/107 , A61N2005/105 , A61N2005/1051
Abstract: A system and method for accurately locating and tracking the position of a target, such as a tumor or the like, within a body. In one embodiment, the system is a target locating and monitoring system usable with a radiation delivery source that delivers a selected doses of radiation to a target in a body. The system includes one or more excitable beacons positionable in or near the target, an external excitation source that remotely excites the beacons to produce an identifiable signal, and a plurality of sensors spaced apart in a known geometry relative to each other. A computer is coupled to the sensors and configured to use the beacon measurements to identify a target isocenter within the target. The computer compares the position of the target isocenter with the location of the machine isocenter. The computer also controls movement of the patient and a patient support device so the target isocenter is coincident with the machine isocenter before and during radiation therapy.
Abstract translation: 一种用于在身体内准确定位和跟踪诸如肿瘤等的靶的位置的系统和方法。 在一个实施例中，该系统是可与辐射递送源一起使用的目标定位和监测系统，其将选定剂量的辐射递送到身体中的目标。 该系统包括可定位在目标中或附近的一个或多个可激励信标，远程激发信标以产生可识别信号的外部激励源，以及以已知几何形状相对于彼此间隔开的多个传感器。 计算机耦合到传感器并且被配置为使用信标测量来识别目标内的目标等角点。 计算机将目标等角点的位置与机器等角点的位置进行比较。 计算机还控制患者和患者支撑装置的运动，使得靶放射线与放射治疗之前和放射治疗期间的机器等角点重合。
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