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公开(公告)号:US20090087842A1
公开(公告)日:2009-04-02
申请号:US11979099
申请日:2007-10-31
申请人: Toshihisa Ohtsuka , Etsuko Rikitsu , Marie Inoue , Eiji Inoue
发明人: Toshihisa Ohtsuka , Etsuko Rikitsu , Marie Inoue , Eiji Inoue
IPC分类号: C12Q1/68 , C07K16/18 , G01N33/566 , C07K14/47 , C07K7/00
CPC分类号: C07K14/47
摘要: The present invention enabled the detection and quantification of CAST, which is localized to synapses and tightly bound to the cytomatrix, and of the mRNA encoding the CAST. Furthermore, it was revealed that CAST functions as a protein scaffold for localizing RIM1 to synapses, contributing as a molecular basis for active zone formation.
摘要翻译: 本发明能够检测和定量CAST,其定位于突触并紧密结合至细胞基质上,以及编码CAST的mRNA。 此外,据透露,CAST作为将RIM1定位于突触的蛋白质支架起作用,作为活性区形成的分子基础。
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公开(公告)号:US07297773B2
公开(公告)日:2007-11-20
申请号:US10747065
申请日:2003-12-30
申请人: Toshihisa Ohtsuka , Etsuko Rikitsu , Marie Inoue , Eiji Inoue
发明人: Toshihisa Ohtsuka , Etsuko Rikitsu , Marie Inoue , Eiji Inoue
CPC分类号: C07K14/47
摘要: The present invention enabled the detection and quantification of CAST, which is localized to synapses and tightly bound to the cytomatrix, and of the mRNA encoding the CAST. Furthermore, it was revealed that CAST functions as a protein scaffold for localizing RIM1 to synapses, contributing as a molecular basis for active zone formation.
摘要翻译: 本发明能够检测和定量CAST,其定位于突触并紧密结合至细胞基质上,以及编码CAST的mRNA。 此外,据透露,CAST作为将RIM1定位于突触的蛋白质支架起作用,作为活性区形成的分子基础。
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3.
公开(公告)号:US07695920B2
公开(公告)日:2010-04-13
申请号:US11979099
申请日:2007-10-31
申请人: Toshihisa Ohtsuka , Etsuko Rikitsu , Marie Inoue , Eiji Inoue
发明人: Toshihisa Ohtsuka , Etsuko Rikitsu , Marie Inoue , Eiji Inoue
IPC分类号: G01N33/53 , G01N33/567 , G01N33/566 , C07K1/00 , C12P21/06
CPC分类号: C07K14/47
摘要: The present invention enabled the detection and quantification of CAST, which is localized to synapses and tightly bound to the cytomatrix, and of the mRNA encoding the CAST. Furthermore, it was revealed that CAST functions as a protein scaffold for localizing RIM1 to synapses, contributing as a molecular basis for active zone formation.
摘要翻译: 本发明能够检测和定量CAST,其定位于突触并紧密结合至细胞基质上,以及编码CAST的mRNA。 此外,据透露,CAST作为将RIM1定位于突触的蛋白质支架起作用,作为活性区形成的分子基础。
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