Presynaptic protein cast
    1.
    发明申请
    Presynaptic protein cast 失效
    突触前蛋白质铸造

    公开(公告)号:US20090087842A1

    公开(公告)日:2009-04-02

    申请号:US11979099

    申请日:2007-10-31

    CPC分类号: C07K14/47

    摘要: The present invention enabled the detection and quantification of CAST, which is localized to synapses and tightly bound to the cytomatrix, and of the mRNA encoding the CAST. Furthermore, it was revealed that CAST functions as a protein scaffold for localizing RIM1 to synapses, contributing as a molecular basis for active zone formation.

    摘要翻译: 本发明能够检测和定量CAST,其定位于突触并紧密结合至细胞基质上,以及编码CAST的mRNA。 此外,据透露,CAST作为将RIM1定位于突触的蛋白质支架起作用,作为活性区形成的分子基础。