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56 条记录 (耗时 0.031 秒)

    Pyrimidyl indoline compound
    2.
    发明授权
    Pyrimidyl indoline compound 失效
    嘧啶二氢吲哚化合物

    公开(公告)号：US08232287B2

    公开(公告)日：2012-07-31

    申请号：US12738200

    申请日：2008-10-15

    申请人： Toshio Kaneko ,  Takeshi Shida ,  Takayuki Baba ,  Koji Matsumoto ,  Kazumasa Aoki

    发明人： Toshio Kaneko ,  Takeshi Shida ,  Takayuki Baba ,  Koji Matsumoto ,  Kazumasa Aoki

    IPC分类号： A01N43/54

    CPC分类号： C07D401/14

    摘要： It is intended to provide a pyrimidyl indoline compound which structurally differs from compounds used as active ingredients in conventional oral hypoglycemic agents and has excellent hypoglycemic effect. The present invention provides a compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof:

    摘要翻译： 旨在提供与在常规口服降血糖药中用作活性成分的化合物结构上不同的嘧啶基二氢吲哚化合物，并且具有优异的降血糖作用。 本发明提供由通式（I）表示的化合物或其药学上可接受的盐：

    Process for producing cyclopropylphenol derivative
    7.
    发明授权
    Process for producing cyclopropylphenol derivative 有权
    环丙基苯酚衍生物的制备方法

    公开(公告)号：US07629494B2

    公开(公告)日：2009-12-08

    申请号：US11887159

    申请日：2006-03-31

    申请人： Yoshihisa Tsukamoto ,  Hiroyuki Komai ,  Toshio Kaneko ,  Takeshi Takada

    发明人： Yoshihisa Tsukamoto ,  Hiroyuki Komai ,  Toshio Kaneko ,  Takeshi Takada

    IPC分类号： C07C69/76 ,  C07C39/17

    CPC分类号： C07C67/287 ,  C07C37/0555 ,  C07C37/20 ,  C07C39/17 ,  C07C39/19 ,  C07C39/245 ,  C07C67/08 ,  C07C67/297 ,  C07C69/017 ,  C07C69/157 ,  C07C69/63 ,  C07C2601/02 ,  C07C39/42

    摘要： A process for producing a cyclopropylphenol represented by of formula (10): wherein R1, R2, R3 and R4 each may represent a hydrogen; Z represents a hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or phenyl; and Y1, Y2 and Y3 each may represent a hydrogen; by reacting a compound of formula (7): wherein X represents a halogen; and V represents a hydrogen or —W—R5, with a metal, metal salt or organometallic compound of formula (8): M2 to obtain a compound of formula (9): and obtaining a compound of formula (10) by hydrolysis in the case wherein V represents —W—R5, wherein W is CO, SO or SO2 and R5 is alkyl, haloalkyl, cycloalkyl, alkenyl, alkynyl, phenyl, alkoxy or haloalkoxy.

    摘要翻译： 一种由式（10）表示的环丙基苯酚的制备方法：其中R1，R2，R3和R4各自表示氢; Z表示氢，烷基，烯基，炔基，环烷基或苯基; Y1，Y2和Y3各自表示氢; 通过使式（7）的化合物：其中X表示卤素; 和V表示氢或-W-R 5与式（8）的金属，金属盐或有机金属化合物：M2，以获得式（9）的化合物：并通过水解得到式（10）的化合物 其中V表示-W-R5，其中W是CO，SO或SO2，R5是烷基，卤代烷基，环烷基，烯基，炔基，苯基，烷氧基或卤代烷氧基。

    Thermal recording sheet
    8.
    发明授权
    Thermal recording sheet 失效
    热敏记录纸

    公开(公告)号：US5322831A

    公开(公告)日：1994-06-21

    申请号：US22261

    申请日：1993-02-25

    申请人： Toshiaki Minami ,  Toshio Kaneko

    发明人： Toshiaki Minami ,  Toshio Kaneko

    IPC分类号： B41M5/337 ,  B41M5/30

    CPC分类号： B41M5/3375

    摘要： A thermal recording sheet having a thermal color developing layer containing a color developer and a colorless or pale colored basic chromogenic dye, which further contains a stabilizer of Formula (I) and a sensitizer of Formula (II) or Formula (III), thereby obtaining a high sensitivity and improved image stability: ##STR1## wherein A indicates ##STR2## R.sup.1 and R.sup.2 individually indicate hydrogen or methyl; .alpha. is 0 or an integer from 1 to 5; .beta. and .gamma. individually indicate an integer from 1 to 5; B indicates ##STR3## C and D individually indicate chlorine, bromine, methyl, methoxy, or ethoxy; and m and n individually indicate 0, 1, or 2; ##STR4##

    摘要翻译： 一种热敏记录片材，其具有含有着色显影剂和无色或浅色基础显色染料的热显色层，其还含有式（I）的稳定剂和式（II）或式（III）的敏化剂，从而获得 （I）其中A表示“IMAGE”或“IMAGE”，R1和R2分别表示氢或甲基; α为0或1至5的整数; β和γ分别表示1至5的整数; B表示 C和D分别表示氯，溴，甲基，甲氧基或乙氧基; 而m和n分别表示0,1或2; （II）式（III）式（III）

    Automobile tire with holes from the tread to the tire sides
    9.
    发明授权
    Automobile tire with holes from the tread to the tire sides 失效
    汽车轮胎具有从胎面到轮胎侧面的孔

    公开(公告)号：US4979549A

    公开(公告)日：1990-12-25

    申请号：US343549

    申请日：1989-04-21

    申请人： Toshio Kaneko

    发明人： Toshio Kaneko

    IPC分类号： B60C11/00 ,  B60C11/03

    CPC分类号： B60C11/032 ,  B60C11/00 ,  B60C11/0323 ,  B29D2030/061

    摘要： This invention provides an automobile tire with communicating holes bored from the tire's tread to the sides of the tire. These holes permit snow or water which has come under the tire to be discharged to the outside through these communicating holes, thereby contributing to prevention of the tire's slip. For more effective discharge of snow or water, a well sliding surface material is applied on the inner surfaces of the communicating holes.

    摘要翻译： 本发明提供一种汽车轮胎，其具有从轮胎胎面向轮胎侧面钻出的连通孔。 这些孔允许通过这些连通孔将落在轮胎下方的雪或水排出到外部，从而有助于防止轮胎的滑动。 为了更有效地排放雪或水，在连通孔的内表面上施加良好的滑动表面材料。

    Method and apparatus for manufacturing curved pipe
    10.
    发明授权
    Method and apparatus for manufacturing curved pipe 失效
    弯管制造方法及装置

    公开(公告)号：US4876872A

    公开(公告)日：1989-10-31

    申请号：US263643

    申请日：1988-10-27

    申请人： Toshio Kaneko

    发明人： Toshio Kaneko

    IPC分类号： B21D7/08 ,  B21D9/12

    CPC分类号： B21D9/125

    摘要： The present invention is directed to a curved pipe manufacturing method comprising the steps of: inserting a curved mandrel into a curved cavity of a fixed die having an entrance opening and an exit opening, the curved mandrel being attached to the distal end of an ejecting rod; forming a curved pipe by pressing a work, with a present rod through the entrance opening of the curved cavity into a curved annular chamber defined by the surfaces of the curved cavity and the mandrel; turning the movable block in one direction so that an ejecting rod attached at its base end with the movable block and concentrically integrated with the mandrel, ejects the mandrel together with the curved pipe from the entrance opening of the fixed die; advancing a movable chuck provided outside the entrance opening for chucking only the curved pipe; turning the movable block to another direction opposite to the one direction so as to return only the mandrel into the curved cavity of the fixed die; and retracting the movable chuck for removing the curved pipe. An apparatus for carrying out the curved pipe manufacturing method is also provided.