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    Oxabicycloheptane derivatives
    2.
    发明授权
    Oxabicycloheptane derivatives 失效
    氧杂双环庚烷衍生物

    公开(公告)号：US4713453A

    公开(公告)日：1987-12-15

    申请号：US19973

    申请日：1987-02-27

    申请人： Toshio Tatsuoka ,  Kenji Suzuki ,  Kayoko Imao ,  Fumio Satoh ,  Seiji Miyano ,  Kunihiro Sumoto

    发明人： Toshio Tatsuoka ,  Kenji Suzuki ,  Kayoko Imao ,  Fumio Satoh ,  Seiji Miyano ,  Kunihiro Sumoto

    IPC分类号： C07D333/00 ,  A61K31/00 ,  A61K31/35 ,  A61K31/352 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/435 ,  A61K31/443 ,  A61K31/4433 ,  A61K31/445 ,  A61K31/495 ,  A61K31/535 ,  A61K31/54 ,  A61P9/00 ,  A61P25/18 ,  A61P25/28 ,  C07D311/94 ,  C07D405/04 ,  C07D405/12 ,  C07D407/04 ,  C07D409/04 ,  C07D487/04 ,  C07D417/00 ,  C07D401/00 ,  C07D405/00 ,  C07D413/00

    CPC分类号： C07D405/04 ,  C07D311/94 ,  C07D405/12 ,  C07D409/04 ,  C07D487/04

    摘要： The present invention relates to a novel oxabicycloheptane derivative of the following formula and a pharmaceutically acceptable salt thereof: ##STR1## where D is a hydrogen atom, a halogen atom, a hydroxyl group, an alkoxy group, an arylalkoxy group, an acyloxy group, a dialkylcarbamoyloxy group or an amidoalkyloxy group; B is a substituted or unsubstituted phenyl, thienyl or furyl group; A is the group ##STR2## (where l is 0 or 1; m and n are each 1 or more, provided that m+n is an interger of 2-8; R.sup.1 is an alkylamino group, a dialkylamino group, an arylalkylamino group, a morpholino group, a thiomorpholino group, a 1-pyrrolidinyl group, a piperidino group, an N-alkylpiperazinyl group, an N-hydroxyalkylpiperazinyl or a pyrrolizidinyl group; and R.sup.2 is a lower alkyl group or a hydroxl group), or the group ##STR3## (where l, m, n, R.sup.1 and R.sup.2 are each the same as defined above), or the group ##STR4## (where R.sup.3 and R.sup.4 which may be the same or different each represents a hydrogen atom, a lower alkyl group, an alkoxycarbonyl group or an acyl group), or the group ##STR5## (where m, l, n, R.sup.1 and R.sup.2 are each the same as defined above). The oxabicycloheptane derivative having the formula defined above and pharmaceutically acceptable salts thereof are effective in ameliorating or eliminating the symptoms that appear either as a result of organic disorders in the brain or on account of pathergasia. These compouds also have antidepressant effects and the useful as psychopharmaceuticals.

    摘要翻译： 本发明涉及下式的新型氧杂双环庚烷衍生物及其药学上可接受的盐：其中D是氢原子，卤素原子，羟基，烷氧基，芳基烷氧基，酰氧基， 二烷基氨基甲酰氧基或酰氨基烷氧基; B是取代或未取代的苯基，噻吩基或呋喃基; A是组（其中l是0或1; m和n各自为1或更多，条件是m + n是2-8的整数; R1是烷基氨基，二烷基氨基，芳基烷基氨基 吗啉基，硫代吗啉基，1-吡咯烷基，哌啶子基，N-烷基哌嗪基，N-羟基烷基哌嗪基或吡咯烷基; R2为低级烷基或羟基），或该基团 ＆lt; IMAGE＆gt;（其中l，m，n，R 1和R 2各自与上述相同）或基团（其中可以相同或不同的R 3和R 4各自表示氢原子，低级烷基 基团，烷氧基羰基或酰基）或基团（其中m，l，n，R 1和R 2各自与上述定义相同）。 具有上述定义的式的氧杂双环庚烷衍生物及其药学上可接受的盐在改善或消除由于脑中有机疾病或由于麻醉引起的症状而有效。 这些药物也具有抗抑郁作用，作为心理药物有用。

    Inter-cylinder air-fuel ratio variation abnormality detection apparatus for multicylinder internal combustion engine
    9.
    发明授权
    Inter-cylinder air-fuel ratio variation abnormality detection apparatus for multicylinder internal combustion engine 有权
    用于多缸内燃机的缸内空燃比变化异常检测装置

    公开(公告)号：US09506416B2

    公开(公告)日：2016-11-29

    申请号：US14095567

    申请日：2013-12-03

    申请人： Kenji Suzuki ,  Hiroshi Miyamoto ,  Yasushi Iwazaki

    发明人： Kenji Suzuki ,  Hiroshi Miyamoto ,  Yasushi Iwazaki

    IPC分类号： F02D41/00 ,  F02D41/14

    CPC分类号： F02D41/1495 ,  F02D41/0085 ,  F02D41/1456

    摘要： A first parameter correlated with a degree of a variation in the output from the air-fuel ratio sensor is calculated. A possible range of a second parameter representing a degree of a variation in air-fuel ratio among the cylinders is determined based on the first parameter. The first parameter is calculated with an air-fuel ratio of a predetermined cylinder forcibly changed. A difference between the unchanged first parameter and the forcibly changed first parameter is determined. A first characteristic representing a relation between the second parameter and the difference is determined based on the possible range of the second parameter and the difference. One of the determination value and the first parameter calculated before the forced change is corrected based on inclination of the determined first characteristic.

    摘要翻译： 计算与空燃比传感器的输出的变化程度相关的第一参数。 基于第一参数来确定表示气缸中的空燃比的变化程度的第二参数的可能范围。 第一参数是以预定的气缸的空燃比强制变化的方式计算的。 确定未改变的第一参数和强制改变的第一参数之间的差异。 基于第二参数的可能范围和差异来确定代表第二参数和差异之间的关系的第一特征。 基于确定的第一特性的倾斜度来校正在强制改变之前计算的确定值和第一参数中的一个。

    Game control device, game program, game control method and game system
    10.
    发明授权
    Game control device, game program, game control method and game system 有权
    游戏控制装置，游戏程序，游戏控制方法和游戏系统

    公开(公告)号：US09485328B2

    公开(公告)日：2016-11-01

    申请号：US13409499

    申请日：2012-03-01

    申请人： Yosuke Abe ,  Minoru Yoneyama ,  Kenji Suzuki ,  Yuji Minohoshi ,  Masaki Morimoto ,  Kiwamu Takahashi ,  Mitsuru Kida ,  Kosuke Shimizu

    发明人： Yosuke Abe ,  Minoru Yoneyama ,  Kenji Suzuki ,  Yuji Minohoshi ,  Masaki Morimoto ,  Kiwamu Takahashi ,  Mitsuru Kida ,  Kosuke Shimizu

    IPC分类号： A63F13/58 ,  H04L29/06 ,  A63F13/812

    CPC分类号： H04L67/38 ,  A63F13/58 ,  A63F13/812 ,  A63F2300/5573 ,  A63F2300/6018

    摘要： The game control device may include a storage unit, a first match-up executing unit, a character ability updating unit, and a second match-up executing unit. The storage unit stores an ability value of each player character. The first match-up executing unit executes a first match-up between two player characters in response to input of a communication terminal, and to determine a result of the first match-up based on the stored ability value of each player character. The character ability updating unit updates, based on the result of the first match-up, the ability values of the two player characters, and causes the storage unit to store the updated ability values. The second match-up executing unit executes a second match-up between player characters independently from the first match-up without input of the communication terminal, and determines a result of the second match-up based on the stored ability value of each player character.

    摘要翻译： 游戏控制装置可以包括存储单元，第一匹配执行单元，字符能力更新单元和第二匹配执行单元。 存储单元存储每个玩家角色的能力值。 第一匹配执行单元响应于通信终端的输入执行两个播放器字符之间的第一匹配，并且基于每个游戏者角色的存储能力值来确定第一匹配的结果。 角色能力更新单元基于第一匹配的结果更新两个玩家角色的能力值，并使存储单元存储更新的能力值。 第二匹配执行单元在没有输入通信终端的情况下独立于第一匹配执行玩家角色之间的第二匹配，并且基于每个玩家角色的存储能力值来确定第二匹配的结果 。