公开(公告)号：US07976917B2

公开(公告)日：2011-07-12

申请号：US10582100

申请日：2004-12-10

申请人： Toyoaki Suzuki ,  Koichi Miura ,  Kenjiro Takayanagi

发明人： Toyoaki Suzuki ,  Koichi Miura ,  Kenjiro Takayanagi

IPC分类号： B29D22/00

CPC分类号： A61J1/2093 ,  A61J1/10 ,  A61J1/2024 ,  A61M2207/00 ,  B32B27/08 ,  B32B27/32 ,  B32B2250/242 ,  B32B2307/31 ,  B32B2307/5825 ,  B32B2439/40 ,  B65D75/5883 ,  B65D81/3266 ,  Y10T428/1334 ,  Y10T428/1352

摘要： Multi-chamber container (1) having its interior partitioned by weak seal portions (3) provided through detachable heat sealing so that multiple contents are accommodated separately from each other, wherein use is made of heat seal layers consisting of a composition comprising two types of propylene copolymers components (component A and component B) from propylene and ethylene and/or a C4-C8 α-olefin which have the following elution properties. Thus, a region wherein a change of seal strength by a change of heat seal temperature is small has a wide temperature range to thereby facilitate controlling of the seal strength at the weak seal portions. The proportion (mass %) of, to total solution, elution according to the TREF method (temperature: 0 to 140° C. and solvent: ODCB) is as follows. With respect to component A: 15 to 50 at 0° C., and 5 to less than 15 at 60 to 90° C. With respect to component B: 0 to 25 at 0° C., and 15 to 70 at 60 to 90° C.

摘要翻译： 多室容器（1）具有通过可拆卸热封提供的弱密封部分（3）的内部分隔，使得多个内容物彼此分开容纳，其中使用的热封层由包含两种 来自丙烯和乙烯的丙烯共聚物组分（组分A和组分B）和/或具有以下洗脱性质的C 4 -C 8α-烯烃。 因此，通过热封温度的变化，密封强度的变化小的区域具有宽的温度范围，从而有助于控制弱密封部分处的密封强度。 相对于总溶液，根据TREF方法（温度：0〜140℃，溶剂：ODCB）的洗脱比例（质量％）如下。 相对于组分A，在0℃为15〜50℃，在60〜90℃为5〜15℃。相对于组分B，0℃为0〜25℃，在60〜 90°C

公开(公告)号：US20070114144A1

公开(公告)日：2007-05-24

申请号：US10582100

申请日：2004-12-10

申请人： Toyoaki Suzuki ,  Koichi Miura ,  Kenjiro Takayanagi

发明人： Toyoaki Suzuki ,  Koichi Miura ,  Kenjiro Takayanagi

IPC分类号： B65D25/08 ,  B65D73/00

CPC分类号： A61J1/2093 ,  A61J1/10 ,  A61J1/2024 ,  A61M2207/00 ,  B32B27/08 ,  B32B27/32 ,  B32B2250/242 ,  B32B2307/31 ,  B32B2307/5825 ,  B32B2439/40 ,  B65D75/5883 ,  B65D81/3266 ,  Y10T428/1334 ,  Y10T428/1352

摘要： Multi-chamber container (1) having its interior partitioned by weak seal portions (3) provided through detachable heat sealing so that multiple contents are accommodated separately from each other, wherein use is made of heat seal layers consisting of a composition comprising two types of propylene copolymers components (component A and component B) from propylene and ethylene and/or a C4-C8 α-olefin which have the following elution properties. Thus, a region wherein a change of seal strength by a change of heat seal temperature is small has a wide temperature range to thereby facilitate controlling of the seal strength at the weak seal portions. The proportion (mass %) of, to total solution, elution according to the TREF method (temperature: 0 to 140° C. and solvent: ODCB) is as follows. With respect to component A: 15 to 50 at 0° C., and 5 to less than 15 at 60 to 90° C. With respect to component B: 0 to 25 at 0° C., and 15 to 70 at 60 to 90° C.

摘要翻译： 多室容器（1）具有通过可拆卸热封提供的弱密封部分（3）的内部分隔，使得多个内容物彼此分开容纳，其中使用的热封层由包含两种 具有以下洗脱性质的丙烯和乙烯和/或C 4 -C 8α-烯烃的丙烯共聚物组分（组分A和组分B）。 因此，通过热封温度的变化，密封强度的变化小的区域具有宽的温度范围，从而有助于控制弱密封部分处的密封强度。 相对于总溶液，根据TREF方法（温度：0〜140℃，溶剂：ODCB）的洗脱比例（质量％）如下。 相对于组分A，在0℃为15〜50℃，在60〜90℃为5〜15℃。相对于组分B，0℃为0〜25℃，在60〜 90°C

公开(公告)号：US08309189B2

公开(公告)日：2012-11-13

申请号：US13057439

申请日：2009-07-27

申请人： Toyoaki Suzuki ,  Koichi Miura ,  Atsushi Mio

发明人： Toyoaki Suzuki ,  Koichi Miura ,  Atsushi Mio

IPC分类号： B29D22/00

CPC分类号： B65D75/5883 ,  A61J1/10 ,  A61J1/1475 ,  B32B27/32 ,  Y10T428/1352

摘要： A multilayered liquid container having a discharge port welded under specified conditions to a sealant, which is constituted of a resin comprising a cycloolefin resin as a main component. The discharge port is composed of: an innermost layer constituted of a resin comprising a cycloolefin as a main component; and a surface layer whose main part is constituted of a resin comprising a specific type of polyethylene as a main component. According to the present invention, there can be provided a multilayered liquid container, which can prevent an effective component of a content fluid from being adsorbed onto or penetrating through not only the container body, but also the resin constituting the discharge port, and enables high temperature sterilization treatment, coupled with the discharge port having high welded strength and drop strength.

摘要翻译： 一种多层液体容器，其具有在特定条件下焊接到由包含环烯烃树脂作为主要成分的树脂构成的密封剂的排出口。 排出口由以下物质构成：由以环烯为主要成分的树脂构成的最内层; 以及其主要部分由包含特定类型的聚乙烯作为主要成分的树脂构成的表面层。 根据本发明，可以提供一种多层液体容器，其能够防止含量流体的有效成分不仅吸附到或穿过容器主体，也可以渗透到构成排出口的树脂上，并且能够高 与排出口相结合，焊接强度高，落下强度高。

公开(公告)号：US08668971B2

公开(公告)日：2014-03-11

申请号：US10548622

申请日：2004-03-11

申请人： Toyoaki Suzuki ,  Koichi Miura

发明人： Toyoaki Suzuki ,  Koichi Miura

IPC分类号： B32B27/32

CPC分类号： A61J1/2093 ,  A61J1/2024 ,  B32B7/04 ,  B32B7/06 ,  B32B7/10 ,  B32B7/12 ,  B32B7/14 ,  B32B27/08 ,  B32B27/325 ,  B32B2270/00 ,  B32B2307/30 ,  B32B2307/31 ,  B32B2307/748 ,  B32B2439/40 ,  B32B2439/46 ,  B32B2439/80 ,  B65D81/3266 ,  Y10T428/13 ,  Y10T428/1352 ,  Y10T428/1359

摘要： A package with multiple chambers, wherein the inside of the package is partitioned into multiple chambers by a weak seal part(s) formed by sealing one sheet having a heat seal layer in at least one surface thereof and the other sheet having a heat seal layer in at least one surface thereof with the heat seal layers facing each other and sealing the peripheral edge parts thereof, and heat-pressing, from the outside of the package, a part of the inner surfaces of the walls of the package with the heat seal layers. The package is characterized in that both of two heat seal layers forming the inner surfaces of the walls include only a cyclic polyolefin resin as a resin ingredient.

摘要翻译： 一种具有多个室的包装，其中通过在其至少一个表面中密封具有热密封层的一个片材而形成的弱密封部分将包装的内部分隔成多个室，而另一个片材具有热封层 在其至少一个表面中，热封层彼此面对并且密封其周边部分，并且从包装的外部将包装的壁的内表面的一部分用热封 层。 该封装的特征在于，形成壁的内表面的两个热封层都仅包含作为树脂成分的环状聚烯烃树脂。

公开(公告)号：US20080044606A1

公开(公告)日：2008-02-21

申请号：US11663886

申请日：2005-09-26

申请人： Kenji Omori ,  Takeshi Nizuka ,  Dai Sudo ,  Manabu Fujimoto ,  Koichi Miura ,  Toyoaki Suzuki ,  Kaori Ikeda ,  Hideji Kashiwagi ,  Hidetoshi Myojyo ,  Masashi Moteki

发明人： Kenji Omori ,  Takeshi Nizuka ,  Dai Sudo ,  Manabu Fujimoto ,  Koichi Miura ,  Toyoaki Suzuki ,  Kaori Ikeda ,  Hideji Kashiwagi ,  Hidetoshi Myojyo ,  Masashi Moteki

IPC分类号： A61J1/00 ,  B32B27/32

CPC分类号： A61J1/2093 ,  A61J1/10 ,  A61J1/2024 ,  A61M2207/00 ,  B32B3/02 ,  B32B15/08 ,  B32B15/20 ,  B32B27/08 ,  B32B27/32 ,  B32B27/325 ,  B32B27/36 ,  B32B2255/10 ,  B32B2255/205 ,  B32B2307/7242 ,  B32B2307/7246 ,  B32B2307/75 ,  B32B2439/46 ,  B32B2439/80 ,  Y10T428/13 ,  Y10T428/1303 ,  Y10T428/1352 ,  Y10T428/1359 ,  Y10T428/139

摘要： A medical container comprising a body for containing a medicament, the body of the medical container being formed of a multilayered film comprising (i) a layer formed of a linear polyolefin and (ii) a layer formed of a cyclic polyolefin adjacent to the layer (i), and the layer (i) formed of the linear polyolefin satisfying the following conditions (a) and/or (b): Condition (a): an amount of a liquid component, which remains after Soxhlet's extraction with organic solvents followed by evaporation of the solvents, is 0.2% by weight or less, and Condition (b): a branching degree of a component, which remains after Soxhlet's extraction with n-hexane followed by evaporation of n-hexane, is 50 or less per 1,000 carbon atoms.

摘要翻译： 一种医疗容器，包括用于容纳药物的主体，所述医疗容器的主体由多层膜形成，所述多层膜包括（i）由线性聚烯烃形成的层和（ii）由邻近所述层的环状聚烯烃形成的层 i）和由线性聚烯烃形成的满足以下条件（a）和/或（b）的层（i））：条件（a）：索格利特有机溶剂萃取后留下的液体组分的量 溶剂的蒸发为0.2重量％以下，条件（b）：在索氏提取后，用正己烷蒸发后残留的成分的分支度为每1000个碳原子数为50以下 原子

公开(公告)号：US08863967B2

公开(公告)日：2014-10-21

申请号：US13143330

申请日：2009-12-24

申请人： Toyoaki Suzuki ,  Koichi Miura

发明人： Toyoaki Suzuki ,  Koichi Miura

IPC分类号： B65D41/20 ,  A61J1/14 ,  B32B27/08 ,  B32B27/32 ,  B29C65/00 ,  B29C65/08 ,  A61J1/10

CPC分类号： A61J1/1475 ,  A61J1/10 ,  B29C65/08 ,  B29C66/712 ,  B32B7/12 ,  B32B27/08 ,  B32B27/304 ,  B32B27/306 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B32B2307/306 ,  B32B2307/31 ,  B32B2307/412 ,  B32B2307/50 ,  B32B2307/518 ,  B32B2307/546 ,  B32B2307/7244 ,  B32B2307/7246 ,  B32B2439/46 ,  B32B2439/80

摘要： A pouring port of a container for liquid at one end of which a rubber stopper allowing the penetration of an injection needle therethrough is embedded, wherein: the pouring port is formed by welding a port part, at least the innermost layer of which forming the discharge channel thereof comprises a resin containing a COP-based resin as the main component, with a stopper body part, which holds the rubber stopper and comprises a resin containing a COP-based resin as the main component, via the resin layers containing the respective COP-based resins as the main component; and at least the resin constituting the stopper body part contains a rubber component in an amount of not more than 30% by mass, or has, in the main chain, a molecular structure represented by general formula (1) [wherein R represents a hydrogen atom or an organic group having 1 to 20 carbon atoms; and n represents an integer equal to or greater than 1] and contains a PE-based resin in an amount of 30% by mass or less, and/or contains an antioxidant in an amount of 0.1% by mass or more and not more than 1.0% by mass.

摘要翻译： 一种用于液体的容器的倾倒口嵌入一个允许注射针穿过的橡胶塞，其中：所述倾倒口是通过焊接端口部分形成的，至少其最内层形成排出 其通道包括含有COP基树脂作为主要成分的树脂，具有塞体部分，其通过包含各COP的树脂层保持橡胶塞并包含含有COP基树脂作为主要成分的树脂 基树脂为主要成分; 并且至少构成塞体部的树脂含有不超过30质量％的橡胶组分，或者在主链中具有由通式（1）表示的分子结构[其中R表示氢 原子或碳原子数为1〜20的有机基团; n表示1以上的整数]，含有30质量％以下的PE系树脂，和/或含有0.1质量％以上且不大于 1.0质量％。

公开(公告)号：US20110135223A1

公开(公告)日：2011-06-09

申请号：US13057439

申请日：2009-07-27

申请人： Toyoaki Suzuki ,  Koichi Miura ,  Atsushi Mio

发明人： Toyoaki Suzuki ,  Koichi Miura ,  Atsushi Mio

IPC分类号： B65D30/02 ,  B65D33/36

CPC分类号： B65D75/5883 ,  A61J1/10 ,  A61J1/1475 ,  B32B27/32 ,  Y10T428/1352

摘要： A multilayered liquid container having a discharge port welded under specified conditions to a sealant, which is constituted of a resin comprising a cycloolefin resin as a main component. The discharge port is composed of: an innermost layer constituted of a resin comprising a cycloolefin as a main component; and a surface layer whose main part is constituted of a resin comprising a specific type of polyethylene as a main component. According to the present invention, there can be provided a multilayered liquid container, which can prevent an effective component of a content fluid from being adsorbed onto or penetrating through not only the container body, but also the resin constituting the discharge port, and enables high temperature sterilization treatment, coupled with the discharge port having high welded strength and drop strength.

摘要翻译： 一种多层液体容器，其具有在特定条件下焊接到由包含环烯烃树脂作为主要成分的树脂构成的密封剂的排出口。 排出口由以下物质构成：由以环烯为主要成分的树脂构成的最内层; 以及其主要部分由包含特定类型的聚乙烯作为主要成分的树脂构成的表面层。 根据本发明，可以提供一种多层液体容器，其能够防止含量流体的有效成分不仅吸附到或穿过容器主体，也可以渗透到构成排出口的树脂上，并且能够高 与排出口相结合，焊接强度高，落下强度高。

公开(公告)号：US20060165928A1

公开(公告)日：2006-07-27

申请号：US10548622

申请日：2004-03-11

申请人： Toyoaki Suzuki ,  Koichi Miura

发明人： Toyoaki Suzuki ,  Koichi Miura

IPC分类号： B32B27/08

CPC分类号： A61J1/2093 ,  A61J1/2024 ,  B32B7/04 ,  B32B7/06 ,  B32B7/10 ,  B32B7/12 ,  B32B7/14 ,  B32B27/08 ,  B32B27/325 ,  B32B2270/00 ,  B32B2307/30 ,  B32B2307/31 ,  B32B2307/748 ,  B32B2439/40 ,  B32B2439/46 ,  B32B2439/80 ,  B65D81/3266 ,  Y10T428/13 ,  Y10T428/1352 ,  Y10T428/1359

摘要： A package with multiple chambers, wherein the inside of the package is partitioned into multiple chambers by a weak seal part(s) formed by sealing one sheet having a heat seal layer in at least one surface thereof and the other sheet having a heat seal layer in at least one surface thereof with the heat seal layers facing each other and sealing the peripheral edge parts thereof, and heat-pressing, from the outside of the package, a part of the inner surfaces of the walls of the package with the heat seal layers. The package is characterized in that both of two heat seal layers forming the inner surfaces of the walls include only a cyclic polyolefin resin as a resin ingredient.

摘要翻译： 一种具有多个室的包装，其中通过在其至少一个表面中密封具有热密封层的一个片材而形成的弱密封部分将包装的内部分隔成多个室，而另一个片材具有热封层 在其至少一个表面中，热封层彼此面对并且密封其周边部分，并且从包装的外部将包装的壁的内表面的一部分用热封 层。 该封装的特征在于，形成壁的内表面的两个热封层都仅包含作为树脂成分的环状聚烯烃树脂。

公开(公告)号：US20110266184A1

公开(公告)日：2011-11-03

申请号：US13143330

申请日：2009-12-24

申请人： Toyoaki Suzuki ,  Koichi Miura

发明人： Toyoaki Suzuki ,  Koichi Miura

IPC分类号： B65D85/00 ,  B32B37/06

CPC分类号： A61J1/1475 ,  A61J1/10 ,  B29C65/08 ,  B29C66/712 ,  B32B7/12 ,  B32B27/08 ,  B32B27/304 ,  B32B27/306 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B32B2307/306 ,  B32B2307/31 ,  B32B2307/412 ,  B32B2307/50 ,  B32B2307/518 ,  B32B2307/546 ,  B32B2307/7244 ,  B32B2307/7246 ,  B32B2439/46 ,  B32B2439/80

摘要： A pouring port of a container for liquid at one end of which a rubber stopper allowing the penetration of an injection needle therethrough is embedded, wherein: the pouring port is formed by welding a port part, at least the innermost layer of which forming the discharge channel thereof comprises a resin containing a COP-based resin as the main component, with a stopper body part, which holds the rubber stopper and comprises a resin containing a COP-based resin as the main component, via the resin layers containing the respective COP-based resins as the main component; and at least the resin constituting the stopper body part contains a rubber component in an amount of not more than 30% by mass, or has, in the main chain, a molecular structure represented by general formula (1) [wherein R represents a hydrogen atom or an organic group having 1 to 20 carbon atoms; and n represents an integer equal to or greater than 1] and contains a PE-based resin in an amount of 30% by mass or less, and/or contains an antioxidant in an amount of 0.1% by mass or more and not more than 1.0% by mass.

摘要翻译： 一种用于液体的容器的倾倒口嵌入一个允许注射针穿过的橡胶塞，其中：所述倾倒口是通过焊接端口部分形成的，至少其最内层形成排出 其通道包括含有COP基树脂作为主要成分的树脂，具有塞体部分，其通过包含各COP的树脂层保持橡胶塞并包含含有COP基树脂作为主要成分的树脂 基树脂为主要成分; 并且至少构成塞体部的树脂含有不超过30质量％的橡胶组分，或者在主链中具有由通式（1）表示的分子结构[其中R表示氢 原子或碳原子数为1〜20的有机基团; n表示1以上的整数]，含有30质量％以下的PE系树脂，和/或含有0.1质量％以上且不大于 1.0质量％。

公开(公告)号：US08029878B2

公开(公告)日：2011-10-04

申请号：US11663886

申请日：2005-09-26

申请人： Kenji Omori ,  Takeshi Nizuka ,  Dai Sudo ,  Manabu Fujimoto ,  Masashi Moteki ,  Toyoaki Suzuki ,  Koichi Miura ,  Kaori Ikeda ,  Hideji Kashiwagi ,  Hidetoshi Myojyo

发明人： Kenji Omori ,  Takeshi Nizuka ,  Dai Sudo ,  Manabu Fujimoto ,  Masashi Moteki ,  Toyoaki Suzuki ,  Koichi Miura ,  Kaori Ikeda ,  Hideji Kashiwagi ,  Hidetoshi Myojyo

IPC分类号： B32B1/02 ,  B32B1/08

CPC分类号： A61J1/2093 ,  A61J1/10 ,  A61J1/2024 ,  A61M2207/00 ,  B32B3/02 ,  B32B15/08 ,  B32B15/20 ,  B32B27/08 ,  B32B27/32 ,  B32B27/325 ,  B32B27/36 ,  B32B2255/10 ,  B32B2255/205 ,  B32B2307/7242 ,  B32B2307/7246 ,  B32B2307/75 ,  B32B2439/46 ,  B32B2439/80 ,  Y10T428/13 ,  Y10T428/1303 ,  Y10T428/1352 ,  Y10T428/1359 ,  Y10T428/139

摘要： A medical container comprising a body for containing a medicament, the body of the medical container being formed of a multilayered film comprising (i) a layer formed of a linear polyolefin and (ii) a layer formed of a cyclic polyolefin adjacent to the layer (i), and the layer (i) formed of the linear polyolefin satisfying the following conditions (a) and/or (b): Condition (a): an amount of a liquid component, which remains after Soxhlet's extraction with organic solvents followed by evaporation of the solvents, is 0.2% by weight or less, and Condition (b): a branching degree of a component, which remains after Soxhlet's extraction with n-hexane followed by evaporation of n-hexane, is 50 or less per 1,000 carbon atoms.

摘要翻译： 一种医疗容器，包括用于容纳药物的主体，所述医疗容器的主体由多层膜形成，所述多层膜包括（i）由线性聚烯烃形成的层和（ii）由邻近所述层的环状聚烯烃形成的层 i）和由线性聚烯烃形成的满足以下条件（a）和/或（b）的层（i））：条件（a）：索格利特有机溶剂萃取后留下的液体组分的量 溶剂的蒸发为0.2重量％以下，条件（b）：在索氏提取后，用正己烷蒸发后残留的成分的分支度为每1000个碳原子数为50以下 原子