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公开(公告)号:US20190127489A1
公开(公告)日:2019-05-02
申请号:US16124650
申请日:2019-01-21
Applicant: UCB PHARMA S.A.
Inventor: David Paul Humphreys , Emma Dave , Laura Griffin , Sam Philip Heywood
Abstract: The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab′ fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
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公开(公告)号:US20160311930A1
公开(公告)日:2016-10-27
申请号:US15058460
申请日:2016-07-06
Applicant: UCB PHARMA S.A.
Inventor: David Paul Humphreys , Emma Dave , Laura Griffin , Sam Philip Heywood
CPC classification number: C07K16/468 , C07K16/00 , C07K16/18 , C07K16/245 , C07K2317/24 , C07K2317/31 , C07K2317/522 , C07K2317/54 , C07K2317/55 , C07K2317/569 , C07K2317/64 , C07K2317/92
Abstract: The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab′ fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
Abstract translation: 本发明提供双特异性抗体融合蛋白,其包含对感兴趣的抗原具有特异性的抗体Fab或Fab'片段,所述片段与至少一种对目的第二抗原具有特异性的单结构域抗体融合。
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公开(公告)号:US10100130B2
公开(公告)日:2018-10-16
申请号:US15792373
申请日:2017-10-24
Applicant: UCB PHARMA S.A.
Inventor: David Paul Humphreys , Emma Dave , Laura Griffin , Sam Philip Heywood
Abstract: The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab′ fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
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公开(公告)号:US09309327B2
公开(公告)日:2016-04-12
申请号:US14101083
申请日:2013-12-09
Applicant: UCB Pharma S.A.
Inventor: David Paul Humphreys , Emma Dave , Laura Griffin , Sam Philip Heywood
CPC classification number: C07K16/468 , C07K16/00 , C07K16/18 , C07K16/245 , C07K2317/24 , C07K2317/31 , C07K2317/522 , C07K2317/54 , C07K2317/55 , C07K2317/569 , C07K2317/64 , C07K2317/92
Abstract: The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab′ fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
Abstract translation: 本发明提供双特异性抗体融合蛋白,其包含对感兴趣的抗原具有特异性的抗体Fab或Fab'片段,所述片段与至少一种对目的第二抗原具有特异性的单结构域抗体融合。
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公开(公告)号:US20180118853A1
公开(公告)日:2018-05-03
申请号:US15792373
申请日:2017-10-24
Applicant: UCB PHARMA S.A.
Inventor: David Paul Humphreys , Emma Dave , Laura Griffin , Sam Philip Heywood
CPC classification number: C07K16/468 , C07K16/00 , C07K16/18 , C07K16/245 , C07K2317/24 , C07K2317/31 , C07K2317/522 , C07K2317/54 , C07K2317/55 , C07K2317/569 , C07K2317/64 , C07K2317/92
Abstract: The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab′ fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
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公开(公告)号:US20140194596A1
公开(公告)日:2014-07-10
申请号:US14101083
申请日:2013-12-09
Applicant: UCB Pharma S.A.
Inventor: David Paul Humphreys , Emma Dave , Laura Griffin , Sam Philip Heywood
IPC: C07K16/46
CPC classification number: C07K16/468 , C07K16/00 , C07K16/18 , C07K16/245 , C07K2317/24 , C07K2317/31 , C07K2317/522 , C07K2317/54 , C07K2317/55 , C07K2317/569 , C07K2317/64 , C07K2317/92
Abstract: The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab′ fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
Abstract translation: 本发明提供双特异性抗体融合蛋白,其包含对感兴趣的抗原具有特异性的抗体Fab或Fab'片段,所述片段与至少一种对目的第二抗原具有特异性的单结构域抗体融合。
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公开(公告)号:US11427650B2
公开(公告)日:2022-08-30
申请号:US16124650
申请日:2019-01-21
Applicant: UCB PHARMA S.A.
Inventor: David Paul Humphreys , Emma Dave , Laura Griffin , Sam Philip Heywood
Abstract: The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab′ fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
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公开(公告)号:US09828438B2
公开(公告)日:2017-11-28
申请号:US15058460
申请日:2016-07-06
Applicant: UCB PHARMA S.A.
Inventor: David Paul Humphreys , Emma Dave , Laura Griffin , Sam Philip Heywood
CPC classification number: C07K16/468 , C07K16/00 , C07K16/18 , C07K16/245 , C07K2317/24 , C07K2317/31 , C07K2317/522 , C07K2317/54 , C07K2317/55 , C07K2317/569 , C07K2317/64 , C07K2317/92
Abstract: The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab′ fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
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