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公开(公告)号：US20130226084A1
公开(公告)日：2013-08-29
申请号：US13693915
申请日：2012-12-04
CPC分类号： A61M5/3234 , A61M5/321 , A61M5/34 , A61M5/50 , A61M2005/3226 , A61M2005/3236 , A61M2207/00 , Y10T29/49826
摘要： A barrel adapter mountable to a syringe barrel includes a barrel tip, a biasing member, a locking mechanism, and a needle assembly. A safety syringe includes a barrel, a plunger assembly, and a barrel adapter. The needle assembly includes a needle, a needle hub, and a needle seal. The needle is configured to pass-through the needle assembly, locking mechanism, biasing member, and barrel tip such that, at one end the needle is within the barrel and at another end the needle passes through an aperture in the barrel tip. The barrel may be substantially cylindrical, having along its longitudinal axis a distal end for drug injection, a proximal end for injection control, and at least a portion of the barrel interior for drug containment. The barrel adapter provides needle retraction mechanisms to the barrel to form a safety syringe. Methods of assembling, manufacturing, and using such syringes are also provided.
摘要翻译： 可安装到注射器筒的桶式适配器包括筒形尖端，偏置构件，锁定机构和针组件。 安全注射器包括筒体，柱塞组件和筒式适配器。 针组件包括针，针座和针密封件。 针被配置成穿过针组件，锁定机构，偏置构件和筒体尖端，使得针在一端处于筒体内并且在另一端处穿过针尖中的孔。 枪管可以是基本上圆柱形的，沿着其纵向轴线具有用于药物注射的远端，用于注射控制的近端，以及用于药物容纳的至少一部分枪管内部。 枪管适配器将针回缩机构提供到枪管以形成安全注射器。 还提供了组装，制造和使用这种注射器的方法。
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公开(公告)号：US20130237910A1
公开(公告)日：2013-09-12
申请号：US13775155
申请日：2013-02-23
IPC分类号： A61M5/32
CPC分类号： A61M37/0069 , A61M5/32 , A61M5/3232 , A61M5/3234 , A61M2005/3131 , A61M2005/323 , A61M2005/3236 , F04C2270/041 , Y10T29/49826
摘要： An implant delivery syringe includes a barrel, a plunger assembly, and a barrel adapter. A barrel adapter mountable to a syringe barrel includes a barrel tip, needle retraction mechanism, needle assembly and stylet slidably disposed within the needle lumen. The needle retraction mechanism includes a biasing member, actuable locking arrangement and locking mechanism. When the actuable locking arrangement is actuated, the biasing member causes the needle to axially translate over the stylet during retraction to cause delivery of an implant to a target location. The stylet may be retracted following delivery. Methods of assembling, manufacturing, and using are also provided.
摘要翻译： 植入物递送注射器包括筒，柱塞组件和筒适配器。 可安装到注射器筒的桶式适配器包括筒尖，针回缩机构，针组件和可滑动地设置在针内腔内的探针。 针回缩机构包括偏置构件，致动锁定装置和锁定机构。 当可致动的锁定装置被致动时，偏压构件使针在收回期间轴向地在管心针上平移以使植入物递送到目标位置。 分娩后可以撤回探针。 还提供了组装，制造和使用的方法。
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公开(公告)号：US20150174339A1
公开(公告)日：2015-06-25
申请号：US14635376
申请日：2015-03-02
发明人： Kevin L. Bokelman , Eduardo Ho , Robert Scott Russo , Brandon J. McKee , John W. Carosi , Christian P. Brandt , Jyoti Gupta , Ramin Mojdehbakhsh
CPC分类号： A61M5/3221 , A61M5/321 , A61M5/3234 , A61M5/34 , A61M2005/3236 , A61M2207/00 , Y10T29/4984
摘要： Barrel adapters for safety syringes include a barrel and a plunger assembly adapted to move within the barrel, a barrel tip adapted to be sealingly engaged with a distal end of the barrel and a needle retraction mechanism barrel having a needle subassembly and an actuator subassembly. The needle subassembly includes a needle, and a needle-over-mold (NOM) through which the needle extends. The needle subassembly is disposed at least partially within the barrel tip, and adapted to move from an injection position in which the needle extends from a distal end of the barrel tip to a retracted position in which the needle is disposed within at least one of the barrel tip or the barrel. The actuator subassembly includes a needle seal, a push-bar, and an actuator surface. The needle retraction mechanism barrel includes a biasing member and an actuable locking arrangement. A syringe includes such barrel adapters.
摘要翻译： 用于安全注射器的桶式适配器包括适于在筒体内移动的桶和柱塞组件，适于与筒的远端密封接合的桶形端头和具有针子组件和致动器子组件的针缩回机构筒。 针子组件包括针和针头延伸的针模（NOM）。 所述针子组件至少部分地设置在所述筒体末端内，并且适于从所述针头从所述筒体末端的远端延伸到其缩回位置的注射位置移动，在所述缩回位置， 桶尖或桶。 致动器子组件包括针密封件，推杆和致动器表面。 针回缩机构筒包括偏置构件和可致动的锁定装置。 注射器包括这种桶适配器。
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公开(公告)号：US20140213972A1
公开(公告)日：2014-07-31
申请号：US14242076
申请日：2014-04-01
CPC分类号： A61M5/3234 , A61M5/321 , A61M5/34 , A61M5/50 , A61M2005/3226 , A61M2005/3236 , A61M2207/00 , Y10T29/49826
摘要： A barrel adapter mountable to a syringe barrel includes a barrel tip, a biasing member, a locking mechanism, and a needle assembly. A safety syringe includes a barrel, a plunger assembly, and a barrel adapter. The needle assembly includes a needle, a needle hub, and a needle seal. The needle is configured to pass-through the needle assembly, locking mechanism, biasing member, and barrel tip such that, at one end the needle is within the barrel and at another end the needle passes through an aperture in the barrel tip. The barrel may be substantially cylindrical, having along its longitudinal axis a distal end for drug injection, a proximal end for injection control, and at least a portion of the barrel interior for drug containment. The barrel adapter provides needle retraction mechanisms to the barrel to form a safety syringe. Methods of assembling, manufacturing, and using such syringes are also provided.
摘要翻译： 可安装到注射器筒的桶式适配器包括筒形尖端，偏置构件，锁定机构和针组件。 安全注射器包括筒体，柱塞组件和筒式适配器。 针组件包括针，针座和针密封件。 针被配置成穿过针组件，锁定机构，偏置构件和筒体尖端，使得针在一端处于筒体内并且在另一端处穿过针尖中的孔。 枪管可以是基本上圆柱形的，沿其纵向轴线具有用于药物注射的远端，用于注射控制的近端，以及用于药物容纳的桶内部的至少一部分。 枪管适配器向枪管提供针回缩机构以形成安全注射器。 还提供了组装，制造和使用这种注射器的方法。
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公开(公告)号：US20150238745A1
公开(公告)日：2015-08-27
申请号：US14708778
申请日：2015-05-11
IPC分类号： A61M37/00
CPC分类号： A61M37/0069 , A61M5/32 , A61M5/3232 , A61M5/3234 , A61M2005/3131 , A61M2005/323 , A61M2005/3236 , F04C2270/041 , Y10T29/49826
摘要： A barrel adapter mountable to a syringe barrel includes a barrel tip, a needle assembly, a stylet assembly slidably disposed within a needle lumen of the needle assembly, and a plug within the lumen of the needle. An implant delivery syringe includes a barrel, a plunger assembly, and the barrel adapter. The syringe may include a needle retraction mechanism having a biasing member and an actuable locking arrangement, the locking arrangement initially maintains the biasing member in an energized position. When the actuable locking arrangement is actuated, the biasing member causes the needle to axially translate over the stylet during retraction to dislodge the plug and cause delivery of an implant to a target location. The plug may be a biodegradable polymer plug such as a water-soluble polymer, PLGA, and/or CAHP. The stylet may be retracted following delivery. Methods of assembling implant delivery syringes with drug implants are also provided.
摘要翻译： 可安装到注射器筒的桶式适配器包括筒尖，针组件，可滑动地设置在针组件的针管内腔内的探针组件，以及针内腔内的塞子。 植入物递送注射器包括筒，柱塞组件和筒适配器。 注射器可以包括具有偏置构件和可致动锁定装置的针回缩机构，锁定装置最初将偏置构件保持在通电位置。 当致动锁定装置被致动时，偏压构件使针在缩回期间轴向地平移通过探针，以移除插塞并且使植入物递送到目标位置。 塞子可以是可生物降解的聚合物塞，例如水溶性聚合物，PLGA和/或CAHP。 分娩后可以撤回探针。 还提供了组装植入式输注注射器与药物植入物的方法。
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公开(公告)号：US09050415B2
公开(公告)日：2015-06-09
申请号：US13775155
申请日：2013-02-23
CPC分类号： A61M37/0069 , A61M5/32 , A61M5/3232 , A61M5/3234 , A61M2005/3131 , A61M2005/323 , A61M2005/3236 , F04C2270/041 , Y10T29/49826
摘要： An implant delivery syringe includes a barrel, a plunger assembly, and a barrel adapter. A barrel adapter mountable to a syringe barrel includes a barrel tip, needle retraction mechanism, needle assembly and stylet slidably disposed within the needle lumen. The needle retraction mechanism includes a biasing member, actuable locking arrangement and locking mechanism. When the actuable locking arrangement is actuated, the biasing member causes the needle to axially translate over the stylet during retraction to cause delivery of an implant to a target location. The stylet may be retracted following delivery. Methods of assembling, manufacturing, and using are also provided.
摘要翻译： 植入物递送注射器包括筒，柱塞组件和筒适配器。 可安装到注射器筒的桶式适配器包括筒尖，针回缩机构，针组件和可滑动地设置在针内腔内的探针。 针回缩机构包括偏置构件，致动锁定装置和锁定机构。 当可致动的锁定装置被致动时，偏压构件使针在收回期间轴向地在管心针上平移以使植入物递送到目标位置。 分娩后可以撤回探针。 还提供了组装，制造和使用的方法。
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公开(公告)号：US08979795B2
公开(公告)日：2015-03-17
申请号：US14207037
申请日：2014-03-12
发明人： Kevin L. Bokelman , Eduardo Ho , Robert Scott Russo , Brandon J. McKee , John W. Carosi , Christian P. Brandt , Jyoti Gupta , Ramin Mojdehbakhsh
CPC分类号： A61M5/3221 , A61M5/321 , A61M5/3234 , A61M5/34 , A61M2005/3236 , A61M2207/00 , Y10T29/4984
摘要： Barrel adapters for safety syringes include a barrel and a plunger assembly adapted to move within the barrel, a barrel tip adapted to be sealingly engaged with a distal end of the barrel and a needle retraction mechanism having a needle subassembly and an actuator subassembly. The needle subassembly includes a needle, and a needle-over-mold (NOM) through which the needle extends. The needle subassembly is disposed at least partially within the barrel tip, and adapted to move from an injection position in which the needle extends from a distal end of the barrel tip to a retracted position in which the needle is disposed within at least one of the barrel tip or the barrel. The actuator subassembly includes a needle seal, a push-bar, and an actuator surface. The needle retraction mechanism includes a biasing member and an actuable locking arrangement. A syringe includes such barrel adapters.
摘要翻译： 用于安全注射器的桶式适配器包括适于在筒体内移动的筒体和柱塞组件，适于与筒体的远端密封接合的筒形末端以及具有针子组件和致动器子组件的针回缩机构。 针子组件包括针和针头延伸的针模（NOM）。 所述针子组件至少部分地设置在所述筒体末端内，并且适于从所述针头从所述筒体末端的远端延伸到其缩回位置的注射位置移动，在所述缩回位置， 桶尖或桶。 致动器子组件包括针密封件，推杆和致动器表面。 针回缩机构包括偏置构件和可致动的锁定装置。 注射器包括这种桶适配器。
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公开(公告)号：US20140276446A1
公开(公告)日：2014-09-18
申请号：US14207037
申请日：2014-03-12
发明人： Kevin L. Bokelman , Eduardo Ho , Robert Scott Russo , Brandon J. McKee , John W. Carosi , Christian P. Brandt , Jyoti Gupta , Ramin Mojdehbakhsh
IPC分类号： A61M5/32
CPC分类号： A61M5/3221 , A61M5/321 , A61M5/3234 , A61M5/34 , A61M2005/3236 , A61M2207/00 , Y10T29/4984
摘要： Barrel adapters for safety syringes include a barrel and a plunger assembly adapted to move within the barrel, a barrel tip adapted to be sealingly engaged with a distal end of the barrel and a needle retraction mechanism having a needle subassembly and an actuator subassembly. The needle subassembly includes a needle, and a needle-over-mold (NOM) through which the needle extends. The needle subassembly is disposed at least partially within the barrel tip, and adapted to move from an injection position in which the needle extends from a distal end of the barrel tip to a retracted position in which the needle is disposed within at least one of the barrel tip or the barrel. The actuator subassembly includes a needle seal, a push-bar, and an actuator surface. The needle retraction mechanism includes a biasing member and an actuable locking arrangement. A syringe includes such barrel adapters.
摘要翻译： 用于安全注射器的桶式适配器包括适于在筒体内移动的筒体和柱塞组件，适于与筒体的远端密封接合的筒形末端以及具有针子组件和致动器子组件的针回缩机构。 针子组件包括针和针头延伸的针模（NOM）。 所述针子组件至少部分地设置在所述筒体末端内，并且适于从所述针头从所述筒体末端的远端延伸到其缩回位置的注射位置移动，在所述缩回位置， 桶尖或桶。 致动器子组件包括针密封件，推杆和致动器表面。 针回缩机构包括偏置构件和可致动的锁定装置。 注射器包括这种桶适配器。
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公开(公告)号：US08702653B2
公开(公告)日：2014-04-22
申请号：US13693915
申请日：2012-12-04
IPC分类号： A61M5/00
CPC分类号： A61M5/3234 , A61M5/321 , A61M5/34 , A61M5/50 , A61M2005/3226 , A61M2005/3236 , A61M2207/00 , Y10T29/49826
摘要： A barrel adapter mountable to a syringe barrel includes a barrel tip, a biasing member, a locking mechanism, and a needle assembly. A safety syringe includes a barrel, a plunger assembly, and a barrel adapter. The needle assembly includes a needle, a needle hub, and a needle seal. The needle is configured to pass-through the needle assembly, locking mechanism, biasing member, and barrel tip such that, at one end the needle is within the barrel and at another end the needle passes through an aperture in the barrel tip. The barrel may be substantially cylindrical, having along its longitudinal axis a distal end for drug injection, a proximal end for injection control, and at least a portion of the barrel interior for drug containment. The barrel adapter provides needle retraction mechanisms to the barrel to form a safety syringe. Methods of assembling, manufacturing, and using such syringes are also provided.
摘要翻译： 可安装到注射器筒的桶式适配器包括筒形尖端，偏置构件，锁定机构和针组件。 安全注射器包括筒体，柱塞组件和筒式适配器。 针组件包括针，针座和针密封件。 针被配置成穿过针组件，锁定机构，偏置构件和筒体尖端，使得针在一端处于筒体内并且在另一端处穿过针尖中的孔。 枪管可以是基本上圆柱形的，沿其纵向轴线具有用于药物注射的远端，用于注射控制的近端，以及用于药物容纳的桶内部的至少一部分。 枪管适配器向枪管提供针回缩机构以形成安全注射器。 还提供了组装，制造和使用这种注射器的方法。
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