公开(公告)号：US11788950B2

公开(公告)日：2023-10-17

申请号：US16479689

申请日：2018-01-26

Applicant: UNIVERSITÄT ULM

Inventor： Daniel Geiger ,  Tobias Neckernuss ,  Othmar Marti

IPC: G01N15/14 ,  G06T7/00 ,  G06T7/269 ,  G01N1/40 ,  G01N15/00 ,  G01N15/10

CPC classification number: G01N15/1475 ,  G01N1/40 ,  G01N15/1431 ,  G01N15/1436 ,  G06T7/0016 ,  G06T7/269 ,  G01N2015/0019 ,  G01N2015/1081 ,  G01N2015/1495 ,  G06T2207/30024

Abstract: Disclosed is a method for analysing cells, in which cells are separated and the individual cells pass via a measurement region of a unit for spatially resolved radiation intensity measurement, wherein, for at least one of the separated cells, when passing via the measurement region, a time sequence of spatial intensity patterns of an electromagnetic radiation emitted from and/or influenced by the cell is created, the optical flow of a respective two of the spatial intensity patterns is calculated for at least one portion of the sequence of intensity patterns using a computer unit, and an evaluation of the calculated optical flows occurs. Also disclosed is a device for analysing cells, comprising a device for separating cells, a unit for spatially resolved radiation intensity measurement, and a computer unit for calculating the optical flow of a respective two of the created intensity patterns, and for evaluating the calculated optical flows.