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公开(公告)号：US20150282733A1
公开(公告)日：2015-10-08
申请号：US14677915
申请日：2015-04-02
Applicant: University of Virginia Patent Foundation
Inventor： Samuel Fielden , Li Zhao , Wilson Miller , Xue Feng , Max Wintermark , Kim Butts Pauly , Craig H. Meyer
CPC classification number: A61B5/055 , A61B5/015 , A61B5/725 , A61B2018/00791 , A61B2090/374 , A61N7/02
Abstract: Aspects of the present disclosure relate to magnetic resonance thermometry. In one embodiment, a method includes acquiring undersampled magnetic resonance data associated with an area of interest of a subject receiving focused ultrasound treatment, and reconstructing images corresponding to the area of interest based on the acquired magnetic resonance data, where the reconstructing uses Kalman filtering.
Abstract translation: 本公开的方面涉及磁共振测温。 在一个实施例中，一种方法包括获取与接收聚焦超声治疗的受试者的感兴趣区域相关联的欠采样磁共振数据，以及基于所获取的磁共振数据重构与所述感兴趣区域相对应的图像，其中所述重建使用卡尔曼滤波。
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2.发明申请公开(公告)号：US20150282719A1
公开(公告)日：2015-10-08
申请号：US14677891
申请日：2015-04-02
Applicant: University of Virginia Patent Foundation
Inventor： Samuel Fielden , Li Zhao , Max Wintermark , Craig H. Meyer
CPC classification number: A61B5/0263 , A61B5/0042 , A61B5/055 , A61B6/5229 , A61B2576/026
Abstract: Aspects of the present disclosure relate to systems and methods for medical imaging that incorporate prior knowledge. Some aspects relate to incorporating prior knowledge using a non-local means filter. Some aspects relate to incorporating prior knowledge for improved perfusion imaging, such as those incorporating arterial spin labeling.
Abstract translation: 本公开的方面涉及包含先前知识的用于医学成像的系统和方法。 一些方面涉及使用非本地平均值过滤器来结合先验知识。 一些方面涉及结合用于改善灌注成像的现有知识，例如并入动脉自旋标记的那些。
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3.发明授权公开(公告)号：US11229810B2
公开(公告)日：2022-01-25
申请号：US15981186
申请日：2018-05-16
Applicant: University of Virginia Patent Foundation , The Board of Trustees of the Leland Stanford Junior University
Inventor： Kevin S. Lee , Edward H. Bertram , Max Wintermark
IPC: A61N7/00 , G01R33/50 , G01R33/48 , A61B5/055 , A61M37/00 , A61B5/00 , G01R33/56 , A61B90/00 , A61B34/00
Abstract: Methods and systems are described for producing non-invasive and targeted neuronal lesions using magnetic resonance and acoustic energy. Imaging data corresponding to a region of interest is obtained, the region of interest within an imaging subject. Information indicative of a target region within the region of interest is received from the obtained imaging data. Focused acoustic energy directed to the target region within the region of interest is generated to disrupt a barrier between a therapeutic agent and parenchymal tissue in response to insonification by the focused acoustic energy, the therapeutic agent comprising a neurotoxin and microbubbles.
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Patent Agency Ranking
公开(公告)号：US20160098835A1
公开(公告)日：2016-04-07
申请号：US14870803
申请日：2015-09-30
Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Inventor： Li Zhao , Xiao Chen , Samuel W. Fielden , Frederick H. Epstein , John P. Mugler, III , Manal Nicolas-Jilwan , Max Wintermark , Craig H. Meyer
IPC: G06T7/00 , G01R33/48 , G01R33/563 , G06T11/00 , G06K9/62
CPC classification number: G06T7/0012 , G01R33/4824 , G01R33/5611 , G01R33/56366 , G06K9/6232 , G06T11/005 , G06T2207/10088 , G06T2207/30104 , G06T2211/412 , G06T2211/424
Abstract: Systems and methods for accelerated arterial spin labeling (ASL) using compressed sensing are disclosed. In one aspect, in accordance with one example embodiment, a method includes acquiring magnetic resonance data associated with an area of interest of a subject, wherein the area of interest corresponds to one or more physiological activities of the subject. The method also includes performing image reconstruction using temporally constrained compressed sensing reconstruction on at least a portion of the acquired magnetic resonance data, wherein acquiring the magnetic resonance data includes receiving data associated with ASL of the area of interest of the subject.
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公开(公告)号：US10722137B2
公开(公告)日：2020-07-28
申请号：US14677915
申请日：2015-04-02
Applicant: University of Virginia Patent Foundation , The Board of Trustees of the Leland Stanford Junior University
Inventor： Samuel Fielden , Li Zhao , Wilson Miller , Xue Feng , Max Wintermark , Kim Butts Pauly , Craig H. Meyer
Abstract: Aspects of the present disclosure relate to magnetic resonance thermometry. In one embodiment, a method includes acquiring undersampled magnetic resonance data associated with an area of interest of a subject receiving focused ultrasound treatment, and reconstructing images corresponding to the area of interest based on the acquired magnetic resonance data, where the reconstructing uses Kalman filtering.
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6.发明申请公开(公告)号：US20180333593A1
公开(公告)日：2018-11-22
申请号：US15981186
申请日：2018-05-16
Applicant: University of Virginia Patent Foundation , The Board of Trustees of the Leland Stanford Junior University
Inventor： Kevin S. Lee , Edward H. Bertram , Max Wintermark
CPC classification number: A61N7/00 , A61B5/0042 , A61B5/055 , A61B5/4839 , A61B5/7485 , A61B2090/374 , A61B2576/026 , A61M37/0092 , A61M2210/0693 , A61N2007/003 , A61N2007/0039 , G01R33/4808 , G01R33/50 , G01R33/5601
Abstract: Methods and systems are described for producing non-invasive and targeted neuronal lesions using magnetic resonance and acoustic energy. Imaging data corresponding to a region of interest is obtained, the region of interest within an imaging subject. Information indicative of a target region within the region of interest is received from the obtained imaging data. Focused acoustic energy directed to the target region within the region of interest is generated to disrupt a barrier between a therapeutic agent and parenchymal tissue in response to insonification by the focused acoustic energy, the therapeutic agent comprising a neurotoxin and microbubbles.
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7.发明授权Systems and methods for accelerated arterial spin labeling using compressed sensing 有权使用压缩感应加速动脉自旋标记的系统和方法公开(公告)号：US09589345B2
公开(公告)日：2017-03-07
申请号：US14870803
申请日：2015-09-30
Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Inventor： Li Zhao , Xiao Chen , Samuel W. Fielden , Frederick H. Epstein , John P. Mugler, III , Manal Nicolas-Jilwan , Max Wintermark , Craig H. Meyer
IPC: G06K9/00 , G06T7/00 , G01R33/563 , G01R33/48 , G06K9/62 , G06T11/00 , A61B5/05 , G01R33/561
CPC classification number: G06T7/0012 , G01R33/4824 , G01R33/5611 , G01R33/56366 , G06K9/6232 , G06T11/005 , G06T2207/10088 , G06T2207/30104 , G06T2211/412 , G06T2211/424
Abstract: Systems and methods for accelerated arterial spin labeling (ASL) using compressed sensing are disclosed. In one aspect, in accordance with one example embodiment, a method includes acquiring magnetic resonance data associated with an area of interest of a subject, wherein the area of interest corresponds to one or more physiological activities of the subject. The method also includes performing image reconstruction using temporally constrained compressed sensing reconstruction on at least a portion of the acquired magnetic resonance data, wherein acquiring the magnetic resonance data includes receiving data associated with ASL of the area of interest of the subject.
Abstract translation: 公开了使用压缩感测加速动脉自旋标记（ASL）的系统和方法。 在一个方面，根据一个示例性实施例，一种方法包括获取与受试者的感兴趣区域相关联的磁共振数据，其中感兴趣区域对应于受试者的一个或多个生理活动。 该方法还包括在所获取的磁共振数据的至少一部分上使用时间上受限的压缩感测重构来执行图像重建，其中获取磁共振数据包括接收与被摄体的感兴趣区域的ASL相关联的数据。
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公开(公告)号：US11647915B2
公开(公告)日：2023-05-16
申请号：US14677891
申请日：2015-04-02
Applicant: University of Virginia Patent Foundation
Inventor： Samuel Fielden , Li Zhao , Max Wintermark , Craig H. Meyer
CPC classification number: A61B5/0263 , A61B5/0042 , A61B5/055 , A61B6/5229 , A61B2576/026
Abstract: Aspects of the present disclosure relate to systems and methods for medical imaging that incorporate prior knowledge. Some aspects relate to incorporating prior knowledge using a non-local means filter. Some aspects relate to incorporating prior knowledge for improved perfusion imaging, such as those incorporating arterial spin labeling.
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