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公开(公告)号：US3642992A
公开(公告)日：1972-02-15
申请号：US3642992D
申请日：1967-09-08
Applicant: UPJOHN CO
Inventor： BABCOCK JOHN C , CAMPBELL J ALLAN
IPC: C07J1/00 , C07J75/00 , C07C169/08
CPC classification number: C07J1/00 , C07J75/00 , Y10S435/843 , Y10S435/911
Abstract: THIS INVENTION RELATES TO NOVEL 7 A-METHYL-17A-ALKYNYLESTRADIOLS AND PROCESSES FOR THEIR PREPARATION; MORE PARTICULARLY TO THOSE COMPOUNDS EMBRACED BY THE FORMULA II
3-(R-O-),7-(CH3-),17-(R''-C*C-),17-(R"-O-)
ESTRA-1,3,5(10)-TRIENE
WHEREIN R IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, THE ACYL RADICAL OF A HYDROCARBON CARBOXYLIC ACID CONTAINING FROM ONE THROUGH TWELVE CARBON ATOMS, AN ALKYL RADICAL CONTAINING FROM ONE THROUGH EIGHT CARBON ATOMS, TETRAHYDROFURANYL, TETRAHYDROPYRANYL, 5-SUBSTITUTED TETRAHYDROPYRANYL AND A SILYL RADICAL OF THE FORMULA
R1-SI(-R2)-R3
WHEREIN R1 R2 AND R3 ARE SELECTED FROM THE GROUP CONSISTING OF ALKYL OF ONE THROUGH SIX CARBON ATOMS AND PHENYL, R'' IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND AN ALKYL RADICAL CONTAINING FROM ONE THROUGH FOUR CARBON ATOMS AND R" IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, THE ACYL RADICAL OF A HYDROCARBON CARBOXYLIC ACID CONTAINING FROM ONE THROUGH TWELVE CARBON ATOMS, AND A SILYL RADICAL OF THE FORMULA
R1-SI(-R2)-R3
WHEREIN R1, R2 AND R3 HAVE THE SAME MEANING AS ABOVE.-
2.发明授权Pharmaceutical compositions comprising 72-methyl estrone and methods for using same 失效包含72-METHYL ESTRONE的药物组合物及其使用方法
公开(公告)号：US3627894A
公开(公告)日：1971-12-14
申请号：US3627894D
申请日：1967-09-08
Applicant: UPJOHN CO
Inventor： BABCOCK JOHN C , CAMPBELL J ALLAN
IPC: C12P33/00 , C07C169/20
CPC classification number: C12P33/00 , Y10S435/843 , Y10S435/911
Abstract: D R A W I N G
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3.发明授权Oral,parenteral and inhalation-therapy with 3,11-dioxo-4,17(20)-cis-pregnadien-21-oic acid,methyl ester,3-oxime 失效口服，使用3,11-二氧代-4,17（20）-CIS-孕酮-21-酸，甲酯，3-氧化物的口服和吸入治疗
公开(公告)号：US3539683A
公开(公告)日：1970-11-10
申请号：US3539683D
申请日：1968-09-26
Applicant: UPJOHN CO
Inventor： JACKSON ROBERT W , BABCOCK JOHN C
IPC: A61K31/573 , C07J41/00 , C07J75/00 , A61K17/00
CPC classification number: A61K31/573 , C07J41/00 , C07J75/00
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公开(公告)号：US3505386A
公开(公告)日：1970-04-07
申请号：US3505386D
申请日：1965-12-29
Applicant: UPJOHN CO
Inventor： BABCOCK JOHN C , BEAL PHILIP F
IPC: C07C69/03 , C07C405/00 , C07D319/08 , C07C69/74
CPC classification number: C07D319/08 , C07C405/00
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公开(公告)号：US3466276A
公开(公告)日：1969-09-09
申请号：US3466276D
申请日：1967-09-05
Applicant: UPJOHN CO
Inventor： CAMPBELL J ALLAN , BABCOCK JOHN C
IPC: A61K31/568 , A61K31/569 , A61K31/57 , A61K31/573 , A61K31/58 , C07J43/00 , C07J75/00 , C07C173/10 , A61K27/00
CPC classification number: A61K31/573 , A61K31/568 , A61K31/569 , A61K31/57 , A61K31/58 , C07J43/00 , C07J75/00
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Patent Agency Ranking
公开(公告)号：US3064013A
公开(公告)日：1962-11-13
申请号：US78605759
申请日：1959-01-12
Applicant: UPJOHN CO
Inventor： BABCOCK JOHN C , ALLAN CAMPBELL J
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公开(公告)号：US3029263A
公开(公告)日：1962-04-10
申请号：US86177559
申请日：1959-12-24
Applicant: UPJOHN CO
Inventor： ALLAN CAMPBELL J , BABCOCK JOHN C
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8.发明授权11alpha-allylated 11beta-hydroxy-5beta-pregnane-3, 20-dione bisoximes and process 失效11α-烯丙基化的11beta羟基-5β-孕烷-3,20-二酮双肟和方法
公开(公告)号：US3019244A
公开(公告)日：1962-01-30
申请号：US81983759
申请日：1959-06-12
Applicant: UPJOHN CO
Inventor： BABCOCK JOHN C , WECHTER WILLIAM J
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公开(公告)号：US2990400A
公开(公告)日：1961-06-27
申请号：US73901058
申请日：1958-06-02
Applicant: UPJOHN CO
Inventor： BABCOCK JOHN C , PEDERSON RAYMOND L
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10.发明授权6-fluoro-17beta-hydroxy-17alpha-lower aliphatic hydrocarbon-1, 4-androstadienes and 6-fluoro-17alpha-lower aliphatic hydrocarbon estradiols 失效6-氟-17β-羟基-17α-低级脂族烃-1,4-雄甾二烯和6-氟-17α-低级脂族烃雌二醇
公开(公告)号：US2877240A
公开(公告)日：1959-03-10
申请号：US74055158
申请日：1958-06-09
Applicant: UPJOHN CO
Inventor： ALLAN CAMPBELL J , PEDERSON RAYMOND L , BABCOCK JOHN C , HOGG JOHN A
CPC classification number: C07J1/00 , C07J75/00 , Y10S435/843 , Y10S435/911 , Y10S435/929
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