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    Stilbene derivatives for ADP-ribosyl cyclase inhibitors
    3.
    发明授权
    Stilbene derivatives for ADP-ribosyl cyclase inhibitors 有权
    ADP-核糖基环化酶抑制剂的二苯乙烯衍生物

    公开(公告)号：US08314082B2

    公开(公告)日：2012-11-20

    申请号：US13149166

    申请日：2011-05-31

    申请人： Uh-Hyun Kim ,  Ho-Jeong Kwon ,  Mie-Jae Im ,  Seon-Young Kim ,  Kwang-Hyun Park ,  So-Young Rah ,  Tae-Sik Nam ,  Byung-Ju Kim ,  Gul Rukhsana

    发明人： Uh-Hyun Kim ,  Ho-Jeong Kwon ,  Mie-Jae Im ,  Seon-Young Kim ,  Kwang-Hyun Park ,  So-Young Rah ,  Tae-Sik Nam ,  Byung-Ju Kim ,  Gul Rukhsana

    IPC分类号： A61K31/05

    CPC分类号： C07C245/08 ,  C07C39/215

    摘要： The present disclosure relates to bisphenyl compounds that are useful for inhibiting the ADP-ribosyl cyclase (ADPR-cyclase). More particularly, the disclosed compounds can be used for treatment and prevention of hypertension, hypertensive cardiac hypertrophy, diabetes, and diabetic nephropathy, in which pathogenesis ADPR-cyclase is involved. The compounds and compositions of the invention can be used for treatment and prevention of cardiovascular disease and related disease states, particularly, hypertension or diabetes related disorders, such as, hypertensive cardiac hypertrophy, diabetic nephropathy, and the like.

    摘要翻译： 本公开涉及可用于抑制ADP-核糖基环化酶（ADPR-环化酶）的双苯基化合物。 更具体地，所公开的化合物可用于治疗和预防涉及发病机制ADPR-环化酶的高血压，高血压心脏肥大，糖尿病和糖尿病性肾病。 本发明的化合物和组合物可用于治疗和预防心血管疾病和相关疾病状态，特别是高血压或糖尿病相关疾病，例如高血压心脏肥大，糖尿病性肾病等。

    METHOD OF REGULATING FERTILIZING ABILITY USING CYCLIC ADP-RIBOSE AND CD38
    4.
    发明申请
    METHOD OF REGULATING FERTILIZING ABILITY USING CYCLIC ADP-RIBOSE AND CD38 审中-公开
    使用循环ADP-RIBOSE和CD38调节营养能力的方法

    公开(公告)号：US20120189607A1

    公开(公告)日：2012-07-26

    申请号：US13357782

    申请日：2012-01-25

    申请人： Uh-Hyun Kim ,  Kwang-Hyun Park ,  Byung-Ju Kim

    发明人： Uh-Hyun Kim ,  Kwang-Hyun Park ,  Byung-Ju Kim

    IPC分类号： A61K31/7076 ,  A61K38/47 ,  A61P15/16 ,  C12N9/24 ,  C07H19/213 ,  A61P15/08

    CPC分类号： A61K38/47 ,  A61K31/00 ,  A61K31/57 ,  A61K31/7076 ,  A61K31/708 ,  A61K2300/00

    摘要： The present invention relates to a pharmaceutical composition for promoting fertilization comprising cyclic ADP-ribose or its derivative, CD38 and to a method of promoting fertilization by promoting the synthesis of cyclic ADP-ribose to increase sperm motility. Also, the present invention relates to a pharmaceutical composition for contraception and a method for inhibiting fertilization, which can inhibit the expression or function of cyclic ADP-ribose to reduce sperm motility, thereby inhibiting fertilization.

    摘要翻译： 本发明涉及用于促进受精的药物组合物，其包括环状ADP-核糖或其衍生物，CD38以及通过促进环状ADP-核糖的合成以增加精子活力来促进受精的方法。 此外，本发明涉及一种用于避孕的药物组合物和抑制受精的方法，其可以抑制环状ADP-核糖的表达或功能以降低精子活力，从而抑制受精。

    Vacuum nozzle control apparatus
    5.
    发明授权
    Vacuum nozzle control apparatus 有权
    真空喷嘴控制装置

    公开(公告)号：US08667671B2

    公开(公告)日：2014-03-11

    申请号：US12760691

    申请日：2010-04-15

    申请人： Byung-Ju Kim

    发明人： Byung-Ju Kim

    IPC分类号： B23P19/00

    CPC分类号： H01L21/6838

    摘要： A vacuum nozzle control apparatus includes a nozzle module having a vacuum hole, a vacuum providing module configured to provide a vacuum to the vacuum hole through a vacuum line, and a vacuum control module configured to selectively form the vacuum in the vacuum hole through the vacuum line, or release the vacuum formed in the vacuum hole through a release line branched off from the vacuum line to expose the vacuum hole to air.

    摘要翻译： 真空喷嘴控制装置包括具有真空孔的喷嘴模块，真空提供模块，被配置为通过真空管线向真空孔提供真空;以及真空控制模块，其配置成通过真空选择性地在真空孔中形成真空 或者通过从真空管线分出的脱模线释放在真空孔中形成的真空，将真空孔暴露于空气。

    Apparatus of mounting component
    6.
    发明授权
    Apparatus of mounting component 有权
    安装部件的装置

    公开(公告)号：US08505194B2

    公开(公告)日：2013-08-13

    申请号：US13206821

    申请日：2011-08-10

    申请人： Jong-eok Ban ,  Byung-Ju Kim

    发明人： Jong-eok Ban ,  Byung-Ju Kim

    IPC分类号： B23P19/00

    CPC分类号： H05K13/0452 ,  H05K13/041 ,  Y10T29/4913 ,  Y10T29/49133 ,  Y10T29/53174 ,  Y10T29/53178 ,  Y10T29/53191

    摘要： An apparatus and method of mounting components are provided. The apparatus for mounting components includes: a component supplying unit which supplies the components so that the components move in at least one line; and a plurality of suction nozzles disposed to approach to or retreat from the components, wherein intervals between the plurality of suction nozzles are changeable so that the suction nozzles correspond to positions of the components. The method of mounting components includes: disposing a plurality of suction nozzles corresponding to the positions of the components; picking up the components by using the suction nozzles adjusting intervals between the suction nozzles; moving the suction nozzles to an upper side of a substrate, on which the components are to be mounted; and putting the components down on the substrate.

    摘要翻译： 提供了一种安装部件的装置和方法。 用于安装部件的装置包括：部件供应单元，其供应部件使得部件至少在一条线上移动; 以及设置成接近或退出部件的多个吸嘴，其中所述多个吸嘴之间的间隔是可变的，使得所述吸嘴对应于所述部件的位置。 安装部件的方法包括：配置与部件位置对应的多个吸嘴; 通过使用吸嘴调节吸嘴之间的间隔来拾取部件; 将吸嘴移动到要安装部件的基板的上侧; 并将组件放在基板上。