公开(公告)号：US12121627B2

公开(公告)日：2024-10-22

申请号：US17953407

申请日：2022-09-27

Applicant: University of Florida Research Foundation, Inc.

Inventor： Michele Viola Manuel ,  Ida E. Svensson Berglund ,  Benjamin G. Keselowsky ,  Malisa Sarntinoranont ,  Harpreet Singh Brar ,  Hunter B. Henderson

IPC: A61L27/04 ,  A61K33/06 ,  A61L27/54 ,  A61L27/58 ,  A61L31/02 ,  A61L31/14 ,  A61L31/16 ,  C22C23/00

CPC classification number: A61L27/047 ,  A61K33/06 ,  A61L27/54 ,  A61L27/58 ,  A61L31/022 ,  A61L31/148 ,  A61L31/16 ,  C22C23/00 ,  A61L2300/258 ,  A61L2300/414 ,  A61L2300/43 ,  A61L2430/02 ,  A61L2430/12 ,  A61L2430/38

Abstract: Embodiments of the present disclosure provide for structures including an alloy of calcium, strontium, and magnesium.

公开(公告)号：US20190194782A1

公开(公告)日：2019-06-27

申请号：US16277173

申请日：2019-02-15

Applicant: University of Florida Research Foundation, Inc.

Inventor： Michele Manuel ,  Josephine Allen ,  Jordan P. Ball ,  Harpreet Singh Brar ,  Ida Svensson BERGLUND

IPC: C22C23/00 ,  C22F1/06 ,  A61L27/58 ,  C22C1/04 ,  C22C23/06 ,  A61L27/30 ,  A61L27/04

CPC classification number: C22C23/00 ,  A61L27/047 ,  A61L27/306 ,  A61L27/58 ,  A61L2400/18 ,  A61L2420/02 ,  C22C1/0408 ,  C22C23/06 ,  C22F1/06

Abstract: Disclosed herein is an article comprising a metal alloy; where the metal alloy comprises a base metal, a second element and a third element; where the base metal is magnesium, calcium, strontium, zinc, or a combination thereof; where the second element is chemically different from the third element; and where the second element and the third element are scandium, yttrium, gadolium, cerium, neodymium, dysporium, or a combination thereof; and a protective layer disposed upon the metal alloy and is reactively bonded to the metal alloy; where the protective layer comprises a base non-metallic derivative, a second non-metallic derivative and a third non-metallic derivative of metals present in the metal alloy; and where the base non-metallic derivative, the second non-metallic derivative and the third non-metallic derivative are all chemically different from one another.

公开(公告)号：US20230037160A1

公开(公告)日：2023-02-02

申请号：US17953407

申请日：2022-09-27

Applicant: University of Florida Research Foundation, Inc.

Inventor： Michele Viola Manuel ,  Ida E. Svensson Berglund ,  Benjamin G. Keselowsky ,  Malisa Sarntinoranont ,  Harpreet Singh Brar ,  Hunter B. Henderson

IPC: A61L27/04 ,  C22C23/00 ,  A61L27/54 ,  A61L27/58 ,  A61K33/06 ,  A61L31/14 ,  A61L31/02 ,  A61L31/16

Abstract: Embodiments of the present disclosure provide for structures including an alloy of calcium, strontium, and magnesium.

公开(公告)号：US11053572B2

公开(公告)日：2021-07-06

申请号：US16277173

申请日：2019-02-15

Applicant: University of Florida Research Foundation, Inc.

Inventor： Michele Manuel ,  Josephine Allen ,  Jordan P. Ball ,  Harpreet Singh Brar ,  Ida Svensson Berglund

IPC: C23C8/10 ,  C22C23/00 ,  C22C23/06 ,  A61L27/04 ,  A61L27/30 ,  A61L27/58 ,  C22C1/04 ,  C22F1/06

Abstract: Disclosed herein is an article comprising a metal alloy; where the metal alloy comprises a base metal, a second element and a third element; where the base metal is magnesium, calcium, strontium, zinc, or a combination thereof; where the second element is chemically different from the third element; and where the second element and the third element are scandium, yttrium, gadolium, cerium, neodymium, dysporium, or a combination thereof; and a protective layer disposed upon the metal alloy and is reactively bonded to the metal alloy; where the protective layer comprises a base non-metallic derivative, a second non-metallic derivative and a third non-metallic derivative of metals present in the metal alloy; and where the base non-metallic derivative, the second non-metallic derivative and the third non-metallic derivative are all chemically different from one another.

公开(公告)号：US10266922B2

公开(公告)日：2019-04-23

申请号：US14901409

申请日：2014-07-03

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： Michele Viola Manuel ,  Josephine Allen ,  Jordan P. Ball ,  Harpreet Singh Brar ,  Ida Svensson Berglund

IPC: C22C23/00 ,  C22C23/06 ,  A61L27/04 ,  A61L27/30 ,  A61L27/58 ,  C22C1/04 ,  C22F1/06

Abstract: Disclosed herein is an article comprising a metal alloy; where the metal alloy comprises a base metal, a second element and a third element; where the base metal is magnesium, calcium, strontium, zinc, or a combination thereof; where the second element is chemically different from the third element; and where the second element and the third element are scandium, yttrium, gadolium, cerium, neodymium, dysporium, or a combination thereof; and a protective layer disposed upon the metal alloy and is reactively bonded to the metal alloy; where the protective layer comprises a base non-metallic derivative, a second non-metallic derivative and a third non-metallic derivative of metals present in the metal alloy; and where the base non-metallic derivative, the non-second metallic derivative and the third non-metallic derivative are all chemically different from one another.

公开(公告)号：US20240408269A1

公开(公告)日：2024-12-12

申请号：US18810922

申请日：2024-08-21

Applicant: University of Florida Research Foundation, Inc.

Inventor： Michele Viola Manuel ,  Ida E. Svensson Berglund ,  Benjamin G. Keselowsky ,  Malisa Sarntinoranont ,  Harpreet Singh Brar ,  Hunter B. Henderson

IPC: A61L27/04 ,  A61K33/06 ,  A61L27/54 ,  A61L27/58 ,  A61L31/02 ,  A61L31/14 ,  A61L31/16 ,  C22C23/00

Abstract: Embodiments of the present disclosure provide for structures including an alloy of calcium, strontium, and magnesium.

公开(公告)号：US11491257B2

公开(公告)日：2022-11-08

申请号：US15381163

申请日：2016-12-16

Applicant: University of Florida Research Foundation, Inc.

Inventor： Michele Viola Manuel ,  Ida E. Svensson Berglund ,  Benjamin G. Keselowsky ,  Malisa Sarntinoranont ,  Harpreet Singh Brar ,  Hunter B. Henderson

IPC: A61L27/04 ,  C22C23/00 ,  A61L31/02 ,  A61L27/54 ,  A61L27/58 ,  A61K33/06 ,  A61L31/14 ,  A61L31/16

Abstract: Embodiments of the present disclosure provide for structures including an alloy of calcium, strontium, and magnesium.

公开(公告)号：US20170095590A1

公开(公告)日：2017-04-06

申请号：US15381163

申请日：2016-12-16

Applicant: University of Florida Research Foundation, Inc.

Inventor： Michele Manuel ,  Ida E. Svensson Berglund ,  Benjamin G. Keselowsky ,  Malisa Sarntinoranont ,  Harpreet Singh Brar ,  Hunter B. Henderson

IPC: A61L27/04 ,  A61K33/06 ,  A61L27/58 ,  C22C23/00 ,  A61L27/54

CPC classification number: A61L27/047 ,  A61K33/06 ,  A61L27/54 ,  A61L27/58 ,  A61L31/022 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/258 ,  A61L2300/414 ,  A61L2300/43 ,  A61L2430/02 ,  A61L2430/12 ,  A61L2430/38 ,  C22C23/00

Abstract: Embodiments of the present disclosure provide for structures including an alloy of calcium, strontium, and magnesium.

公开(公告)号：US20170080121A1

公开(公告)日：2017-03-23

申请号：US15366263

申请日：2016-12-01

Applicant: University of Florida Research Foundation, Inc.

Inventor： Michele Manuel ,  Harpreet Singh Brar ,  Ida E. Svensson Berglund ,  Malisa Sarntinoranont ,  Benjamin G. Keselowsky

IPC: A61L27/04 ,  A61L31/02 ,  C22C23/00 ,  A61L27/54 ,  A61L31/16 ,  A61L27/58 ,  A61L31/14

CPC classification number: A61K33/06 ,  A61L27/047 ,  A61L27/54 ,  A61L27/58 ,  A61L31/022 ,  A61L31/148 ,  A61L31/16 ,  A61L2430/02 ,  A61L2430/12 ,  A61L2430/38 ,  C22C23/00

Abstract: Disclosed herein is a non-toxic, bioresorbable, magnesium based alloy for use in production of implants. Specifically exemplified herein are alloy embodiments useful for orthopedic implants. Also disclosed are alloy materials that incorporate magnesium, calcium and strontium.