公开(公告)号：US20230200382A1

公开(公告)日：2023-06-29

申请号：US17979857

申请日：2022-11-03

Applicant: University of Florida Research Foundation, Inc.

Inventor： Brent S. Sumerlin ,  Shaun Paul Jensen ,  Megan R. Hill ,  Mingsheng Chen ,  Gloria A. Moore ,  Zhenli L. HE ,  Sangwoo Park

IPC: A01N25/28 ,  C05G5/30 ,  A01N25/10

CPC classification number: A01N25/28 ,  C05G5/37 ,  A01N25/10

Abstract: Embodiments of the present disclosure provide for compositions including polymer particles, methods of making compositions, methods of using the composition, stimuli-responsive methods of delivering agents, and the like.

公开(公告)号：US11627738B2

公开(公告)日：2023-04-18

申请号：US16066926

申请日：2016-12-29

Applicant: University of Florida Research Foundation, Inc.

Inventor： Brent S. Sumerlin ,  Shaun Paul Jensen ,  Megan R. Hill ,  Mingsheng Chen ,  Gloria A Moore ,  Zhenli L He ,  Sangwoo Park

IPC: A01N25/28 ,  A01N25/10 ,  C05G5/30

Abstract: Embodiments of the present disclosure provide for compositions including polymer particles, methods of making compositions, methods of using the composition, stimuli-responsive methods of delivering agents, and the like.

公开(公告)号：US20200010798A1

公开(公告)日：2020-01-09

申请号：US16492293

申请日：2018-03-09

Applicant: University of Florida Research Foundation, Inc.

Inventor： Wallace Gregory Sawyer ,  Sangwoo Park ,  Christopher S. O'Bryan ,  Christopher P. Kabb ,  Brent S. Sumerlin ,  Thomas Ettor Angelini

IPC: C12N5/00 ,  C08F2/38 ,  C12P21/00

Abstract: Microgel particles for use in a three-dimensional cell growth medium are described. The microgel particles may be swellable and may have properties conducive to improved function and health of cells distributed within the three-dimensional cell growth medium. Related compositions, systems, and methods are also described. Also provided is a plurality of microgel particles and a liquid cell culture medium, wherein the microgel particles are swelled with the liquid cell culture medium to form a granular gel. Also provided is a method of preparing a three-dimensional cell growth medium is disclosed. The method may comprise: mixing a plurality of microgel particles, such as those described above, in a liquid cell culture medium. Also provided is a method of placing cells in a three-dimensional cell growth medium is disclosed. Also provided is a method of synthesizing a protein is disclosed.