公开(公告)号：US20220054711A1

公开(公告)日：2022-02-24

申请号：US17519195

申请日：2021-11-04

申请人： University of Florida Research Foundation, Inc.

发明人： Wallace Gregory Sawyer ,  Thomas Ettor Angelini ,  Steven C. Ghivizzani ,  C. Parker Gibbs

IPC分类号： A61L27/38 ,  A61F2/28

摘要： Described herein are methods and apparatus for constructing tissue replacements, such as bone replacements that may be used to repair damaged or missing segments of bone, such as may occur in wound repair or as a repair of a congenital anomaly. These methods involve a three-dimensional (3D) cell growth medium made from a yield stress material that allows cells and structures to be easily deposited and positioned.

公开(公告)号：US11027483B2

公开(公告)日：2021-06-08

申请号：US15757122

申请日：2016-09-02

申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. ,  Joshua Muse ,  Meghan Hughes ,  Carl David Crane

发明人： Joshua Muse ,  Meghan Hughes ,  Carl David Crane ,  Thomas Ettor Angelini ,  Kyle D. Schulze ,  Tapomoy Bhattacharjee ,  Wallace Gregory Sawyer ,  Curtis Taylor

IPC分类号： B29C64/106 ,  B33Y70/00 ,  B33Y10/00 ,  B33Y30/00 ,  B29C67/00 ,  B29C64/118 ,  B29C48/50 ,  B29C48/92 ,  B29C48/05

摘要： Described herein are various embodiments of a valve that may be opened and closed using a thixotropic or “stress yield” material, or other material that temporarily changes phase upon application of energy to the material. More particularly, some embodiments may include a valve that is opened and closed using a granular gel that is a temporary phase change material.

公开(公告)号：US10957040B2

公开(公告)日：2021-03-23

申请号：US16679689

申请日：2019-11-11

申请人： University of Florida Research Foundation, Inc.

发明人： Tanmay P. Lele ,  Wallace Gregory Sawyer

IPC分类号： G06T7/00 ,  C12N15/10 ,  B01L3/00 ,  C12Q1/6851 ,  G01N33/50 ,  C40B40/06 ,  C12Q1/6841

摘要： Embodiments of the present disclosure provide for methods and systems for preparing chromosomal spread for a selected cell so that chromosomal spreads and/or translocations can be correlated with the selected cell.

公开(公告)号：US20200082528A1

公开(公告)日：2020-03-12

申请号：US16679689

申请日：2019-11-11

申请人： University of Florida Research Foundation, Inc.

发明人： Tanmay P. Lele ,  Wallace Gregory Sawyer

IPC分类号： G06T7/00 ,  C40B40/06 ,  G01N33/50 ,  C12Q1/6851 ,  B01L3/00 ,  C12Q1/6841 ,  C12N15/10

摘要： Embodiments of the present disclosure provide for methods and systems for preparing chromosomal spread for a selected cell so that chromosomal spreads and/or translocations can be correlated with the selected cell.

公开(公告)号：US20160272917A1

公开(公告)日：2016-09-22

申请号：US15151621

申请日：2016-05-11

申请人： University of Florida Research Foundation, Inc.

发明人： Wallace Gregory Sawyer ,  Jennifer Vail

IPC分类号： C10M147/02 ,  C10M107/24

CPC分类号： C10M169/041 ,  C10M107/24 ,  C10M107/32 ,  C10M107/38 ,  C10M109/00 ,  C10M147/02 ,  C10M2209/1013 ,  C10M2211/063 ,  C10M2213/02 ,  C10N2220/08 ,  C10N2220/086 ,  C10N2230/06 ,  C10N2250/08 ,  Y10S977/773 ,  Y10T428/254

摘要： Briefly described, embodiments of this disclosure include articles and methods of making articles.

公开(公告)号：US09365791B2

公开(公告)日：2016-06-14

申请号：US14462787

申请日：2014-08-19

申请人： University of Florida Research Foundation, Inc.

发明人： Wallace Gregory Sawyer ,  Jennifer Vail

IPC分类号： F16C33/20 ,  C10M169/00 ,  B32B5/16 ,  B32B17/08 ,  C10M107/38 ,  C10M107/32 ,  C10M109/00

CPC分类号： C10M169/041 ,  C10M107/24 ,  C10M107/32 ,  C10M107/38 ,  C10M109/00 ,  C10M147/02 ,  C10M2209/1013 ,  C10M2211/063 ,  C10M2213/02 ,  C10N2220/08 ,  C10N2220/086 ,  C10N2230/06 ,  C10N2250/08 ,  Y10S977/773 ,  Y10T428/254

摘要： Briefly described, embodiments of this disclosure include articles and methods of making articles.

摘要翻译： 简要描述，本公开的实施例包括制造物品的制品和方法。

公开(公告)号：US20160000575A1

公开(公告)日：2016-01-07

申请号：US14768540

申请日：2014-01-31

申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

发明人： Wallace Gregory Sawyer ,  Brandon Alexander Krick

IPC分类号： A61F2/44

CPC分类号： A61F2/4425 ,  A61F2/442 ,  A61F2002/30224 ,  A61F2002/30235 ,  A61F2002/30299 ,  A61F2002/30563 ,  A61F2002/30565 ,  A61F2240/002

摘要： Disclosed herein is an invertebral disc prosthesis comprising a first cantilever arm; the first cantilever arm comprising a shaft that is affixed to a disc; a second cantilever arm that comprises a plurality of rods that contact the disc; the plurality of rods being equidistant from a central axis of the shaft; and a third cantilever arm that comprises a platform to which are attached a plurality of rings; the rings being concentrically disposed about the shaft; the rings being in operative communication with each other; where the plurality of rods contacts the platform; and where the second cantilever arm has more degrees of freedom than the first cantilever arm, while the third cantilever arm has a number of degrees of freedom that are greater than or equal to the number of degrees of the second cantilever arm.

摘要翻译： 本文公开了一种椎间盘假体，其包括第一悬臂; 所述第一悬臂包括固定到盘的轴; 第二悬臂，其包括接触所述盘的多个杆; 所述多个杆与所述轴的中心轴线等距; 以及第三悬臂，其包括附接有多个环的平台; 所述环围绕所述轴同心地设置; 所述环彼此操作性地通信; 其中所述多个杆接触所述平台; 并且其中所述第二悬臂具有比所述第一悬臂更多的自由度，而所述第三悬臂具有大于或等于所述第二悬臂的度数的多个自由度。

公开(公告)号：US20140026628A1

公开(公告)日：2014-01-30

申请号：US13950917

申请日：2013-07-25

申请人： University of Florida Research Foundation, Inc.

发明人： Wallace Gregory Sawyer ,  Kyle Gene Rowe ,  Alexander Rejender Webber

IPC分类号： C05G3/00

CPC分类号： C05G3/0088 ,  C05G3/0029 ,  C05G3/0041

摘要： Embodiments of the present disclosure provide for coated particles, compositions including coated particles, methods for making coated particles, methods of reducing dust, and the like.

摘要翻译： 本公开的实施方案提供了涂覆颗粒，包括涂覆颗粒的组合物，制备涂覆颗粒的方法，减少粉尘的方法等。

公开(公告)号：US11998461B2

公开(公告)日：2024-06-04

申请号：US17745382

申请日：2022-05-16

申请人： University of Florida Research Foundation, Inc. ,  Brian P. Bartlett

发明人： Wallace Gregory Sawyer ,  Brian P. Bartlett ,  Derek L. Hood

IPC分类号： A61F2/60 ,  A61F2/54 ,  A61F2/64 ,  A61F2/76 ,  A61F2/78 ,  A61F2/50

CPC分类号： A61F2/78 ,  A61F2/54 ,  A61F2/60 ,  A61F2/76 ,  A61F2002/5006 ,  A61F2002/5033 ,  A61F2002/5083 ,  A61F2002/543 ,  A61F2002/607 ,  A61F2002/7875 ,  A61F2002/7887

摘要： Various examples are provided for modular prosthetic devices and their use. In one example, a device includes a chassis assembly including a joint portion; and an interchangeable module that can be removably attached to the chassis assembly. The interchangeable modules can be configured for use in a wide variety of applications. The interchangeable modules can be quickly exchanged for different activities.

公开(公告)号：US11964422B2

公开(公告)日：2024-04-23

申请号：US17245140

申请日：2021-04-30

申请人： University of Florida Research Foundation, Inc.

发明人： Joshua Muse ,  Meghan Hughes ,  Carl David Crane ,  Thomas Ettor Angelini ,  Kyle D. Schulze ,  Tapomoy Bhattacharjee ,  Wallace Gregory Sawyer ,  Curtis Taylor

IPC分类号： B29C64/106 ,  B29C48/05 ,  B29C48/50 ,  B29C48/92 ,  B29C64/118 ,  B29C67/00 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y70/00

CPC分类号： B29C64/106 ,  B29C48/501 ,  B29C64/118 ,  B29C67/00 ,  B33Y10/00 ,  B33Y30/00 ,  B29C48/05 ,  B29C48/92 ,  B29C2948/92904 ,  B33Y70/00

摘要： Described herein are various embodiments of a valve that may be opened and closed using a thixotropic or “stress yield” material, or other material that temporarily changes phase upon application of energy to the material. More particularly, some embodiments may include a valve that is opened and closed using a granular gel that is a temporary phase change material.