公开(公告)号：US11826311B2

公开(公告)日：2023-11-28

申请号：US17230527

申请日：2021-04-14

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Yifei Jin

IPC: A61J3/07 ,  B65D81/32 ,  B05B1/30 ,  A61K9/48 ,  A23P30/25

CPC classification number: A61J3/074 ,  A61J3/07 ,  A61K9/4808 ,  B05B1/3086 ,  A23P30/25 ,  B65D81/3216

Abstract: Embodiments of the present disclosure provide for coaxial nozzles, capsule fabrication systems comprising coaxial nozzles, and methods of capsule fabrication using capsule fabrication systems. In certain embodiments, coaxial nozzle configurations, capsule fabrication systems, and methods as described herein can be used for multi-layered capsule fabrication.

公开(公告)号：US20210236697A1

公开(公告)日：2021-08-05

申请号：US17150038

申请日：2021-01-15

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Kaidong Song ,  Ashley M. Compaan ,  Wenxuan Chai

IPC: A61L27/52 ,  A61L27/22 ,  A61L27/36

Abstract: Described herein are injectable composite inks composed of a hydrogel continuous phase with a plurality of microgels present within the hydrogel continuous phase. The inks described herein have unique chemical and physical properties that enable them to be printed into a number of different types of articles. The articles produced by the injectable composite inks have numerous medical applications.

公开(公告)号：US20180370116A1

公开(公告)日：2018-12-27

申请号：US16007081

申请日：2018-06-13

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Kyle Will Christensen

IPC: B29C64/112 ,  B29C64/393 ,  B29C64/245 ,  B29C64/209

Abstract: Various examples of systems and methods are provided for three-dimensional (3D) printing of reactive materials. In one aspect, among others, a system includes a droplet generation assembly comprising a first printhead coupled to a first reservoir of reactive material and a second printhead coupled to a second reservoir of reactive material, the first and second printheads configured to produce jets of reactive material droplets; a jet alignment assembly configured to adjust orientation of the first and second printheads to align the jets of the reactive material droplets for intersection at a collision point; and a motion control assembly configured to adjust positioning of the first and second printheads and a platform configured to position a deposition location at the collision point.

公开(公告)号：US11964075B2

公开(公告)日：2024-04-23

申请号：US17150038

申请日：2021-01-15

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Kaidong Song ,  Ashley M. Compaan ,  Wenxuan Chai

IPC: A61L27/52 ,  A61L27/22 ,  A61L27/36

CPC classification number: A61L27/52 ,  A61L27/222 ,  A61L27/3687 ,  A61L2400/06

Abstract: Described herein are injectable composite inks composed of a hydrogel continuous phase with a plurality of microgels present within the hydrogel continuous phase. The inks described herein have unique chemical and physical properties that enable them to be printed into a number of different types of articles. The articles produced by the injectable composite inks have numerous medical applications.

公开(公告)号：US11207841B2

公开(公告)日：2021-12-28

申请号：US16334202

申请日：2017-09-18

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Yifei Jin ,  Ashley M. Compaan ,  Wenxuan Chai ,  Chengcheng Liu

IPC: B29C64/40 ,  B29C64/106 ,  B29C64/20 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y70/00 ,  B29C64/112 ,  B29C64/00 ,  B29K105/00

Abstract: Embodiments of the present disclosure provide for systems and methods of three dimensional printing including a precursor build material comprising a hydrogel precursor and a support material, wherein the precursor build material has a gel-like state when a stress applied to the precursor build material is less than a yield stress, wherein the precursor build material has a free-flow state when the stress applied to the precursor build material is above the yield stress, wherein when the stress applied to the precursor build material changes from above the yield stress to below the yield stress, the precursor build material returns to the gel-like state.

公开(公告)号：US11731343B2

公开(公告)日：2023-08-22

申请号：US16007081

申请日：2018-06-13

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Kyle Will Christensen

IPC: B29C64/112 ,  B29C64/393 ,  B29C64/209 ,  B33Y70/00 ,  B41J2/045 ,  B41J2/21 ,  B29C64/245 ,  B33Y30/00 ,  B33Y50/02 ,  B33Y80/00 ,  B33Y10/00

CPC classification number: B29C64/112 ,  B29C64/209 ,  B29C64/393 ,  B33Y70/00 ,  B41J2/04505 ,  B41J2/2135 ,  B29C64/245 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y50/02 ,  B33Y80/00

Abstract: Various examples of systems and methods are provided for three-dimensional (3D) printing of reactive materials. In one aspect, among others, a system includes a droplet generation assembly comprising a first printhead coupled to a first reservoir of reactive material and a second printhead coupled to a second reservoir of reactive material, the first and second printheads configured to produce jets of reactive material droplets; a jet alignment assembly configured to adjust orientation of the first and second printheads to align the jets of the reactive material droplets for intersection at a collision point; and a motion control assembly configured to adjust positioning of the first and second printheads and a platform configured to position a deposition location at the collision point.

公开(公告)号：US20210236386A1

公开(公告)日：2021-08-05

申请号：US17230527

申请日：2021-04-14

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Yifei Jin

IPC: A61J3/07 ,  B05B1/30 ,  A61K9/48

Abstract: Embodiments of the present disclosure provide for coaxial nozzles, capsule fabrication systems comprising coaxial nozzles, and methods of capsule fabrication using capsule fabrication systems. In certain embodiments, coaxial nozzle configurations, capsule fabrication systems, and methods as described herein can be used for multi-layered capsule fabrication.

公开(公告)号：US20190275746A1

公开(公告)日：2019-09-12

申请号：US16334202

申请日：2017-09-18

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Yifei Jin ,  Ashley M. Compaan ,  Wenxuan Chai ,  Chengcheng Liu

IPC: B29C64/40 ,  B29C64/106 ,  B29C64/20 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y70/00

Abstract: Embodiments of the present disclosure provide for systems and methods of three dimensional printing including a precursor build material comprising a hydrogel precursor and a support material, wherein the precursor build material has a gel-like state when a stress applied to the precursor build material is less than a yield stress, wherein the precursor build material has a free-flow state when the stress applied to the precursor build material is above the yield stress, wherein when the stress applied to the precursor build material changes from above the yield stress to below the yield stress, the precursor build material returns to the gel-like state.

公开(公告)号：US20180353384A1

公开(公告)日：2018-12-13

申请号：US16001386

申请日：2018-06-06

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Yifei Jin

IPC: A61J3/07 ,  A61K9/48 ,  B05B1/30

CPC classification number: A61J3/074 ,  A61K9/4808 ,  B05B1/3086 ,  B65D81/3216

Abstract: Embodiments of the present disclosure provide for coaxial nozzles, capsule fabrication systems comprising coaxial nozzles, and methods of capsule fabrication using capsule fabrication systems. In certain embodiments, coaxial nozzle configurations, capsule fabrication systems, and methods as described herein can be used for multi-layered capsule fabrication.