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1.发明授权公开(公告)号：US11553839B2
公开(公告)日：2023-01-17
申请号：US16228979
申请日：2018-12-21
发明人： Kirill V. Larin , Manmohan Singh , Jiasong Li , Zhaolong Han , Michael D. Twa
摘要： Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.
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2.发明公开公开(公告)号：US20230210371A1
公开(公告)日：2023-07-06
申请号：US18072838
申请日：2022-12-01
发明人： Kirill V. Larin , Manmohan Singh , Jiasong Li , Zhaolong Han , Michael D. Twa
CPC分类号： A61B3/18 , A61B3/165 , A61B3/102 , A61B5/7289 , A61B5/7246
摘要： Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.
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3.发明授权公开(公告)号：US12029492B2
公开(公告)日：2024-07-09
申请号：US18072838
申请日：2022-12-01
发明人： Kirill V. Larin , Manmohan Singh , Jiasong Li , Zhaolong Han , Michael D. Twa
CPC分类号： A61B3/165 , A61B3/102 , A61B3/18 , A61B5/0066 , A61B5/7246 , A61B5/7289 , A61B3/107
摘要： Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.
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