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公开(公告)号：US09883847B2
公开(公告)日：2018-02-06
申请号：US14608859
申请日：2015-01-29
发明人： Jeffrey S. Wolf , Amal Isaiah
CPC分类号： A61B8/085 , A61B5/4818 , A61B7/003 , A61B8/0858 , A61B8/145 , A61B8/15 , A61B8/4227 , A61B8/4461 , A61B8/4494 , A61B8/5223 , A61B8/543 , A61B8/56
摘要： Techniques for ultrasound location of obstructions during OSA include an ultrasound transducer array configured, upon receipt of a signal, to obtain first data that supports a plurality of ultrasound images representing a corresponding plurality of cross sections of an airway in a neck of a subject. Second data is received automatically on a processor, from an apnea event sensor set that is configured to collect automatically the second data sensitive to an apnea event in the subject. An apnea event is detected automatically on the processor based on the second data. In response to detecting the apnea event, the signal is automatically sent to the ultrasound transducer array, wherein the signal is the signal that causes the ultrasound transducer array to obtain the first data. Image data based on the first data is automatically stored in a computer-readable medium.
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公开(公告)号：US20200345267A1
公开(公告)日：2020-11-05
申请号：US16964736
申请日：2019-01-24
发明人： Amal Isaiah , Jeffrey S. Wolf , Stephen Restaino
摘要： A method and system detects a hypoxic condition during an obstruction of an airway of a subject to detect and treat obstructive sleep apnea (OSA) in the subject. The method and system includes an organ stimulating transducer configured for placement in a vicinity of an organ of the subject to stimulate the organ and remove the obstruction when OSA is detected.
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公开(公告)号：US20210322699A1
公开(公告)日：2021-10-21
申请号：US17249633
申请日：2021-03-08
发明人： Jeffrey S. Wolf , Amal Isaiah
摘要： Techniques for automated titration of CPAP device for a subject include receiving multiple ultrasound images representing a cross section of an airway in a neck of the subject at corresponding different times. Multiple different positive pressure values imposed by a device on the airway of the subject are also received at each of the corresponding times. For each of the ultrasound images, a mask of pixels associated with an air-tissue interface is automatically formed, and a value of a statistic of pixels within the mask is automatically determined. A titration pressure for a continuous positive airway pressure (CPAP) device is automatically determined based on the positive pressures and the value of the statistic for each of the ultrasound images. Output data that indicates the titration pressure for the CPAP device is presented on a display device, such as by operating the CPAP device itself at the titration pressure.
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公开(公告)号：US20150209001A1
公开(公告)日：2015-07-30
申请号：US14608859
申请日：2015-01-29
发明人： Jeffrey S. Wolf , Amal Isaiah
CPC分类号： A61B8/085 , A61B5/4818 , A61B7/003 , A61B8/0858 , A61B8/145 , A61B8/15 , A61B8/4227 , A61B8/4461 , A61B8/4494 , A61B8/5223 , A61B8/543 , A61B8/56
摘要： Techniques for ultrasound location of obstructions during OSA include an ultrasound transducer array configured, upon receipt of a signal, to obtain first data that supports a plurality of ultrasound images representing a corresponding plurality of cross sections of an airway in a neck of a subject. Second data is received automatically on a processor, from an apnea event sensor set that is configured to collect automatically the second data sensitive to an apnea event in the subject. An apnea event is detected automatically on the processor based on the second data. In response to detecting the apnea event, the signal is automatically sent to the ultrasound transducer array, wherein the signal is the signal that causes the ultrasound transducer array to obtain the first data. Image data based on the first data is automatically stored in a computer-readable medium.
摘要翻译： 在OSA期间用于超声定位障碍物的技术包括在接收到信号时配置的超声换能器阵列，以获得支持多个超声图像的第一数据，所述第一数据表示对象的颈部中气道的相应多个横截面。 第二数据在处理器上自动接收，该呼吸暂停事件传感器组被配置为自动收集对受试者中的呼吸暂停事件敏感的第二数据。 基于第二数据在处理器上自动检测呼吸暂停事件。 响应于检测到呼吸暂停事件，信号被自动发送到超声换能器阵列，其中该信号是使超声换能器阵列获得第一数据的信号。 基于第一数据的图像数据被自动存储在计算机可读介质中。
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公开(公告)号：US12070304B2
公开(公告)日：2024-08-27
申请号：US16964736
申请日：2019-01-24
发明人： Amal Isaiah , Jeffrey S. Wolf , Stephen Restaino
CPC分类号： A61B5/0826 , A61B5/14542 , A61B5/4818 , A61B5/4836 , A61B5/6822 , A61B5/7405 , A61B5/742 , A61B5/7455 , A61N7/00 , A61N2007/0026 , A61N2007/0052 , A61N2007/0073
摘要： A method and system detects a hypoxic condition during an obstruction of an airway of a subject to detect and treat obstructive sleep apnea (OSA) in the subject. The method and system includes an organ stimulating transducer configured for placement in a vicinity of an organ of the subject to stimulate the organ and remove the obstruction when OSA is detected.
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公开(公告)号：US10974004B2
公开(公告)日：2021-04-13
申请号：US16075687
申请日：2017-02-02
发明人： Jeffrey S. Wolf , Amal Isaiah
摘要： Techniques for automated titration of CPAP device for a subject include receiving multiple ultrasound images representing a cross section of an airway in a neck of the subject at corresponding different times. Multiple different positive pressure values imposed by a device on the airway of the subject are also received at each of the corresponding times. For each of the ultrasound images, a mask of pixels associated with an air-tissue interface is automatically formed, and a value of a statistic of pixels within the mask is automatically determined. A titration pressure for a continuous positive airway pressure (CPAP) device is automatically determined based on the positive pressures and the value of the statistic for each of the ultrasound images. Output data that indicates the titration pressure for the CPAP device is presented on a display device, such as by operating the CPAP device itself at the titration pressure.
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7.发明申请公开(公告)号：US20200038609A1
公开(公告)日：2020-02-06
申请号：US16075687
申请日：2017-02-02
发明人： Jeffrey S. Wolf , Amal Isaiah
摘要： Techniques for automated titration of CPAP device for a subject include receiving multiple ultrasound images representing a cross section of an airway in a neck of the subject at corresponding different times. Multiple different positive pressure values imposed by a device on the airway of the subject are also received at each of the corresponding times. For each of the ultrasound images, a mask of pixels associated with an air-tissue interface is automatically formed, and a value of a statistic of pixels within the mask is automatically determined. A titration pressure for a continuous positive airway pressure (CPAP) device is automatically determined based on the positive pressures and the value of the statistic for each of the ultrasound images. Output data that indicates the titration pressure for the CPAP device is presented on a display device, such as by operating the CPAP device itself at the titration pressure.
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